DENGUE IN PEDIATRIC
Introduction
• Acute Viral infection cause Biphasic Fever with
Hemorrhagic Rash and
characteristic
Thrombocytopenia.
• Also Known as Break
Bone Fever.
• The vast majority of
dengue cases are
children less than 15
years of age. Dengue
causes a spectrum of
illness from mild fever to severe disease with
plasma leakage and shock
• WHO currently estimates there may be 50 million
cases of dengue infection worldwide every year.
• Dengue fever is an acute febrile disease, endemic
in tropics, caused by four closely related Dengue
viruses 1,2,3,4 of Flaviviridae family.
• It is transmitted to humans by the Aedes
Aegypti mosquito, which unlike the malaria
causing mosquito Anopheles feeds only during
the day.
• The disease is now spreading internationally.
• Dengue is not contagious. It spreads only
through the bite of an infected mosquito.
Incubation Period : 1 to 7 days
Mode of Transmission
Pathophysiology
Symptoms in Different Phase
Types
Diagnosis
• CBC with increased Lymphocytes and reduced
thrombocytopenia (S100,000/mm³)
• NS-1 Antibody
• Dengue Antibody test - IgM
• Hematocrit increased >20%
• Pleural Effusion (by chest radiograph)
• Hypoalbuminemia
Vaccine
• World's first dengue vaccine was invented in Spain's
Saint Louis University and Mexico was the first
country to approve it.
• However, India has not approved any dengue
vaccine produced by other countries so far.
Prevention
• Prevention of mosquito bite
• Use mosquito proof net for sleeping
• Use mosquito repellent ointments
Curative Treatment
• Antimicrobial therapy - No specific Antiviral
treatment but antibiotic may bend for super
added bacterial infections
• Symptomatic treatment for cough and Fever
with Acetaminophene and analgesie
• Adequate rest
• Adequate nutrition
• Adequate hydration for fluid replacement
• Fluid Administration - RL (Ringer Lactate),
Normal Saline (NS)