Schizophrenia Schizophrenia Causes distorted and bizarre thoughts, perceptions, emotions, movements, and behavior Cannot be defined as a single illness; rather, schizophrenia is thought of as a syndrome or as a disease process with many different varieties and symptoms Schizophrenia Usually diagnosed in late adolescence or early adulthood Peak incidence of onset o Men 15 to 25 years of age o Women 25 to 35 years of age Diagnosis Two (or more) of the following, each present for a significant portion of time during a 1-month period (or less if successfully treated). At least one of these must be (1), (2), or (3): o Delusions o Hallucinations o Disorganized speech (e.g., frequent derailment or incoherence) o Grossly disorganized or catatonic behavior o Negative symptoms (i.e., diminished emotional or avolition) Schizophrenia Symptoms are divided into two major categories o Positive symptoms/signs o Negative symptoms/sign Medication may control positive, but negative symptoms often persist Schizophrenia Positive Symptoms Ambivalence – Holding contradictory beliefs Associative looseness – Fragmented ideas Delusions Echopraxia – Imitiation of movements of others Flight of ideas – me_irl Hallucinations – False sensory perceptions Ideas of Reference – False impressions that events of special meaning for the person Perseveration Bizarre Behavior Schizophrenia Negative Symptoms Alogia – “Poverty of Speech” Anhedonia – No joy or pleasure in life Apathy – No care Asociality Blunted affect – Restricted range of emotion Catatonia – Motionless as if in a trance Flat affect Avolition – Absence of will, ambition, or drive Inattention – Can’t concentrate Etiology Focus on genetic factors, neuroanatomic and neurochemical factors (structure and function of the brain), and immunovirology Schizophrenia Psychopharmacology Does not cure, manages Antipsychotics (also known as neuroleptics) o Decrease psychotic symptoms o 1st generation Dopamine antagonists; target the positive signs of schizophrenia nd o 2 generation Diminish positive signs but also lessens the negative signs Schizophrenia Psychopharmacology Side effects o Extrapyramidal side effects (acute dystonic reactions, akathisia, parkinsonism) Dystonic reaction Spasm in discrete muscle groups Protrusion of tongue, dysphagia, laryngeal and pharyngeal spasm Treatment – diphenhydramine IM or IV or benztropine IM Pseudoparkinsonism Shuffling gait, masklike facies, muscle stiffness, drooling, akinesia Appear first few days after starting or increasing dosage Akathisia Characterized by restless movement, pacing, inability to remain still, and the client’s report of inner restlessness o Propranolol; benzodiazepines Schizophrenia Psychopharmacology Side Effects o Tardive dyskinesia Lip smacking, tongue protrusion, chewing, blinking, grimacing, and choreiform movements of the limbs and feet Can contribute to social isolation Irreversible Schizophrenia Psychopharmacology Tardive Dyskinesia o Abnormal Involuntary Movement Scale (AIMS) Used to screen for symptoms of movement disorders If increased score on the AIMS, the nurse should notify the physician Schizophrenia Psychopharmacology Side effects (continued) o Neuroleptic malignant syndrome Serious and frequently fatal Muscle rigidity, high fever, increased muscle enzymes, and leukocytosis Treated by stopping medication Schizophrenia Psychopharmacology Side effects (continued) o Agranulocytosis Clozapine Fever, malaise, ulcerative sore throat, leukopenia Can occur 18-24 weeks after initiation of therapy; weekly WBC weekly for 1st 6 months Must be discontinued immediately Schizophrenia Psychopharmacology Side effects (continued) o o o o o Weight gain Sedation Photosensitivity Anticholinergic symptoms Table 16-2 Videbeck (interventions r/t SE) Psychosocial Treatment Individual and group therapy o Supportive in nature o Opportunity for social contact and meaningful relationships o Focus on topics of concern Psychosocial Treatment Family education and therapy o Known to diminish the negative effects of schizophrenia o Reduces relapse rate o Helps make families part of the treatment plan Psychosocial Treatment Family support groups o Supportive environment that helps them cope with the many difficulties presented when a loved one has schizophrenia Nursing Process – Assessment Do not make assumptions about the client’s abilities or limitations solely based on the diagnosis of schizophrenia History o “How do you usually spend your time?” “Can you describe what you do each day?” Nursing Process – Assessment History (continued) o Age of onset o Previous suicide attempts History of violence or aggression o Use of current support systems o Client’s perception of his or her current situation Nursing Process – Assessment General appearance, motor behavior, speech o Some appear normal in terms of dress and posture o Odd or bizarre behavior; disheveled and unkempt o Strange or inappropriate clothing o Restless, unable to sit still o Agitation, pacing, catatonia Nursing Process – Assessment General appearance, motor behavior, speech (cont’d) o Seemingly purposeless gestures o Odd facial expressions o Imitate movements and gestures of someone whom he/she is observing (echopraxia) o Rambling speech o General slowing of all movements Unusual Speech Patterns of Clients with Schizophrenia Clang associations o Ideas that are related to one another based on sound or rhyming rather than meaning Neologisms o Words invented by the client Verbigeration o Repetition of words or phrases that may or may not have meaning to the listener Unusual Speech Patterns of Clients with Schizophrenia Echolalia o Client’s imitation or repetition of what the nurse says Stilted language o Use of words or phrases that are flowery, excessive, and pompous Word salad o Combination of jumbled words and phrases that are disconnected or incoherent and make no sense to the listener. Nursing Process – Assessment Mood o o o o Flat affect; blunted affect; masklike Silly, characterized by laughter for no reason Expression/emotions incongruent with situation Depressed; no pleasure or joy in life Feel all-knowing, all-powerful Nursing Process - Assessment Thought process o Thought blocking Stop talking in the middle of a sentence and remain silent for several seconds to 1 minute o Thought withdrawal Others are taking their thoughts o Thought insertion Others are placing thoughts in their mind against their will o Thought broadcasting State that they believe others can hear their thoughts Nursing Process - Assessment Delusions o Fixed, false beliefs with no basis in reality o Common characteristic is the direct, immediate, and total certainty with which the client holds these beliefs o External contradictory information or facts cannot alter these delusional beliefs Types of Delusions Persecutory/Paranoid delusions o Belief that “others” are planning to harm him or her or are spying, following, ridiculing, or belittling the client in some way o Religious delusions Center around the second coming of Christ or another significant religious figure or prophet Types of Delusions Grandiose delusions o Characterized by the client’s claim to association with famous people or celebrities, or the client’s belief that he or she is famous or capable of great feats. Nursing Process – Assessment Hallucinations o Can involve the five senses and bodily sensations o Can be threatening and frightening for the client o Initially, the client perceives them as real, but later in the illness may recognize them as hallucinations Nursing Process – Assessment Hallucinations o Auditory hallucinations Involve hearing sounds, most often voices, talking to or about the client o Visual hallucinations Seeing images that do not exist at all Nursing Process - Assessment Sensorium o Clients are commonly disoriented to time and sometimes place during episodes of psychosis o Depersonalization Client feels detached from his or her behavior Feels as if his or her body belongs to someone else Nursing Process - Assessment Intellectual Processes o Difficulty with abstract thinking Client may not understand what is being said and misinterpret instructions Nursing Process – Assessment Self-Concept o Loss of ego boundaries Client’s lack of a clear sense of where his or her own body, mind, and influence end and where those aspects of other animate and inanimate objects begin Nursing Process - Assessment Roles and relationships o Social isolation Due to delusions, hallucinations, loss of ego boundaries Problems with trust and intimacy o Frustration in attempting to fulfill roles Nursing Process - Assessment Physiological and Self-Care Considerations o Inattention to grooming and hygiene common o Fail to perform basic activities of daily living o May fail to recognize sensations such as hunger or thirst o Sleep problems are common o Assess daily living skills and functional abilities Goals/Outcomes Acute, psychotic phase o The client will not injure him/herself or others o The client will establish contact with reality o The client will interact with others in the environment o The client will express thoughts/feelings in a safe, socially acceptable manner o The client will participate in prescribed therapeutic interventions Goals/Outcomes Continued care after the stabilization of acute symptoms o The client will participate in the prescribed regimen o The client will maintain adequate routines for sleeping and food and fluid intake o The client will demonstrate independence in self-care activities Goals/Outcomes Continued care after the stabilization of acute symptoms (continued) o The client will communicate effectively with others in the community to meet his or her needs o The client will seek or accept assistance to meet his or her needs when indicated Interventions Promoting the safety of the client and others Observe for signs of building agitation or escalating behavior Institute interventions to protect the client, nurse, and others in the environment Administering medication; moving the client to a quiet, less stimulating environment; and in extreme situations, temporarily using seclusion or restraints. Interventions Establishing a therapeutic relationship o Takes time and the nurse must be patient o Provide explanations that are clear, direct, and easy to understand o Eye contact, relaxed body posture, facial expressions that convey interest and concern o Tell the client your name and call the client by name Interventions Therapeutic Communication o Maintain nonverbal communication with the client, especially when verbal communication not successful o Active listening Listen for themes, ask clarifying questions, explore the meaning of the client’s statements Therapeutic Communication Example Nurse: “How are you feeling today?” (using a broad opening statement) Client: “Invisible.” Nurse: “Can you explain that to me?” (seeking clarification) Client: “Oh, it doesn’t matter.” Nurse: “I’m interested in how you feel; I’m just not sure I understand.” (offering self/seeking clarification) Client: “It doesn’t mean much.” Nurse: “Let me see if I can understand. Do you feel like you’re being ignored, that no one is really listening?” (verbalizing the implied) Interventions Interventions for delusional thoughts o Avoid openly confronting the delusion or arguing with the client about it o The nurse must also avoid reinforcing the delusional belief by “playing along” with what the client says o Distraction techniques, such as listening to music, watching television, writing, or talking to friends, are useful Interventions Interventions for delusional thoughts (continued) o Present and maintain reality “I have seen no evidence of that.” (presenting reality) “It doesn’t seem that way to me.” (casting doubt) Interventions Interventions for hallucinations o Determine what the client is experiencing “I don’t hear any voices; what are you hearing?” (presenting reality/seeking clarification) “I don’t see anything, but you must be frightened. You are safe here in the hospital.” (presenting reality/translating into feelings) Interventions Interventions for hallucinations o Dismissal intervention Talk back to the voices forcefully Client and Family Teaching How to manage illness and symptoms Recognizing early signs of relapse Developing a plan to address relapse signs Importance of maintaining prescribed med regimen and follow-up Avoid alcohol and other drugs Client and Family Teaching (continued) Self-care and proper nutrition Teaching social skills through education, role modeling, and practice Seeking assistance to avoid or manage stressful situations Counseling and educating family/significant others about clinical course and need for ongoing support Importance of maintaining contact with the community and participating in supportive organizations Early Signs of Relapse Impaired cause-and-effect reasoning Impaired information processing Poor nutrition Lack of sleep Lack of exercise Fatigue Poor social skills, social isolation, loneliness Interpersonal difficulties Lack of control, irritability Mood swings Ineffective medication management Low self-concept Looks and acts different Hopeless feelings Loss of motivation Anxiety and worry Disinhibition Increased negativity Neglecting appearance Forgetfulness Medication Management (Of relapse) Determine the barriers to compliance for each client o Difficulty remembering when and if they did take med -> Pill box or chart o Practical barriers (cost, transportation, refills) o Side effects Eating proper diet, drinking enough fluids, stool softener, sucking on hard candy, using sunscreen Medication Management Determine the barriers to compliance for each client (continued) o Dislikes taking them or believes they don’t need them May feel the medication is unnecessary when they feel well Client and Family Education Related to Medication Management Drink sugar-free fluids and eat sugar-free hard candy to ease the anticholinergic effects of dry mouth Constipation can be prevented or relieved by increasing intake of water and bulkforming foods in the diet and by exercising; stool softeners Use sunscreen to prevent burning. Avoid long periods of time in the sun, and wear protective clothing. Rising slowly from a lying or sitting position prevents falls from orthostatic hypotension or dizziness due to a drop in blood pressure. Monitor the amount of sleepiness or drowsiness you experience. Client and Family Education Related to Medication Management If you forget a dose of antipsychotic medication, take it if the dose is only 3 to 4 hours late. If the missed dose is more than 4 hours late or the next dose is due, omit the forgotten dose Evaluation Have the client’s psychotic symptoms disappeared? If not, can the client carry out his or her daily life despite the persistence of some psychotic symptoms? Does the client understand the prescribed medication regimen? Is he or she committed to adherence to the regimen? Evaluation Does the client possess the necessary functional abilities for community living? Are community resources adequate to help the client live successfully in the community? Is there a sufficient aftercare or crisis plan in place to deal with recurrence of symptoms or difficulties encountered in the community? Evaluation Are the client and family adequately knowledgeable about schizophrenia? Does the client believe he or she has a satisfactory quality of life?