Schizophrenia By K. Cox ATU Nature of Disorder •Premorbid personality •Acute onset •Premorbid behavior –The schizoid personality –The prodromal phase Symptoms •Positive –Delusions –Hallucinations Negative Symptoms •Flat affect •Ambivalence •Anhedonia •Alogia Neurocognitive Impairment •Memory •Vigilance •Verbal Fluency •Executive Functioning •Disorganized Thinking •Disorganized Behavior Phases of Schizophrenia •Initial Diagnosis –Diagnostic criteria •General symptoms •Social/Occupational dysfunction •Duration •Schizoaffective and Mood Disorder exclusion •Substance/general medical condition exclusion Phases Continued •Adaptation •Relapse Epidemiology •Risk factors •Age of onset •Gender differences •Ethnic and cultural differences •Familial Differences Comorbidity •Substance abuse and depression •Disordered water balance Etiology •Biologic Theories –Neuroanatomic findings –Familial patterns –Neurodevelopment –Neurotransmitters Etiology Continued •Psychological Theories •Social Theories Interdisciplinary Treatment •Nursing •Psychiatry •Psychology •Social Work •Occupational and Recreational therapy •Pastoral counselors Suicide Assessment Psychosis or Depression Family Response •Life long battle •Shock •Fear •Care and concern •Disbelief Nursing Management •Assessment –Thorough history –Physical examination –Substance use/abuse –Risk for self injury –Medication history –Positive and negative symptoms –Cognitive impairments –Support systems (family/friends) –Social functioning –Mental Status Nursing Diagnoses/Interventions •Biological –Self-care deficit –Disturbed sleep patterns –Constipation –Imbalanced nutrition –Fluid volume excess Nursing Diagnoses/Interventions •Biologic continued –Pharmacology – Antipsychotic drugs •Therapeutic effect •Newer drugs •Monitoring •Adherence •Side Effects –Extrapyramidal Symptoms (EPS) »Parkinsonism »Dystonic reactions »Akathisia »Tardive dyskinesia Side Effects Continued –Orthostatic hypotension –Dry mouth –Blurred vision –Photosensitivity –Constipation –Urinary retention –Agranulocytosis –Neuroleptic malignant syndrome Nursing Diagnoses/Interventions •Psychological –Disturbed thought processes –Disturbed sensory perception –Low self-esteem –Risk for violence –Ineffective coping –Knowledge deficit Nursing Diagnoses/Interventions •Social –Social Isolation –Ineffective Role Performance –Disabled Family Coping Evaluation •Decreased symptoms •Support systems •Patient education •Relapse prevention