Thoracic Diseases Classification for Chest X-Ray Images using Deep Learning Techniques Sarath Chandra Gollamudi School of Computing National College of Ireland Dublin x19193581@student.ncirl.ie Mansi Udani School of Computing National College of Ireland Dublin x19186088@student.ncirl.ie I. MOTIVATION AND RESEARCH QUESTION A. Motivation In 2oth century, the world is experiencing the usefulness of Machine Learning which is an application of Artificial Intelligence. It helps the computers to take the decision on their own and to find the underlying patterns in the data by training with the machine learning algorithms. On the other hand, Deep Learning is the subfield of that which helps for analysing a large amount of unstructured and structured data. The deep learning algorithms are introduced with inspiration by the structure and functioning of the brain which is called artificial neural networks. There are different deep learning algorithms which can be used for different kind of datasets. The main motivation for choosing this topic is that chest x-ray exams are most cost effective medical examinations. To minimise the cost, we could use the machine learning algorithms by training the models with the real time images. On the other hand, the medical industry is one of the high priority sectors and people need the highest level of care and this data being analysed by experts. After solving the realworld problems successfully by implementing deep learning techniques which provides exciting solutions and accurate results in the medical industry. In this paper, we have used the deep learning CNN algorithm for the analysis. B. Research Question To predict and classify the diseases using the chest x-ray images with deep learning techniques. II. INITIAL LITERATURE REVIEW Chest X-ray (CXR) is a conventional medical imaging technology essentially used for diagnosing thoracic diseases like lung nodule, pneumonia, atelectasis and many more. The effortless and speedy feature of CXR makes it popular choice for clinical examinations. Reading X-rays can be tricky as it is error-prone and requires an expertise. Automatic detection of diseases using deep learning approaches has provided great value [1]. In radiology, the most conducted exams are on the Chest radiographs which helps for the detection of various diseases related to the high mortality. In this paper [2] Yaniv Bar with his colleagues examines the detection of pathology in chest radiographs using machine learning algorithms, which are SVM and CNN (Convolutional Neural Network) with the dataset consist of 433 images. The results showed that CNN performs better over SVM with an AUC of 0.87 to 0.94 for the different pathologies. Wu et al. [3] proposes an automatic approach to save time and cost by labelling findings on chest x- rays. This task is Shashikumar Madihalli Byrappa School of Computing Natioanl College of Ireland Dublin x18173837@student.ncirl.ie performed manually by radiologists to detect finding locations. To address this problem, automatic labeling of chest x-ray images is done by leveraging radiology reports. The first stage involves lung segmentation of normal patient to mark six lung zones with standardized bounding boxes. The second stage involves labeling each lung zone positive or negative by associating it to the radiology report. Using this approach, an average annotation precision of 0.896 and recall of 0.881 is evaluated. In the world population, people are suffering from many diseases, the TB (Tuberculosis) is one of them caused by a Mycobacterium. In the paper [4] Wai Yan Nyein Naing, Zaw Z. Htike performed research on detecting TB using different machine learning algorithms SVM, Fuzzy Logic, and ANN on different datasets of chest x-rays. The results showed that the accuracy rate of SVM is 78.3% and 84% respectively for the first and second datasets. On the other hand, there were 50% correct classifications for the image’s dataset. For the examination of cancer disease detection of mitosis in breast cancer histology images is very complex and time is taken process. In the paper [5] D. C. Ciresan with his colleagues has performed research to automate and make it robust in the detection process using deep learning technique DNN (Deep max-pooling convolutional neural network). The results showed that the precision, recall, and F1 score are with 0.88, 0.70, and 0.782, respectively. In recent years Deep learning is widely used in the medical field to classify the medical signals or images. Convolutional Neural Networks are broadly used for image classification problems. In this study classification of chest X-ray images, we used CNN for its high performance [6]. Similarly, Wang et al. [7] explore neural networks along with external medical knowledge to construct a novel method called knowledge-guided deep zoom neural network (KGZNet). The disease classification focuses to gradually zoom on discriminative regions from coarse to fine. A Lung region generator captures lung region areas where thoracic diseases occur. Then a lesion region generator augments focus on lesion area in lung regions. Finally, disease classification is obtained by fusing features model with medical discriminative features knowledge. The dataset achieves an average AUC of 0.878. Earlier image diagnosis is one of the biggest problems in the medical field. Deep learning methods facilitate doctors to overcome this problem by classifying the images to corresponding diseases and treat them to the corresponding diseases. In this paper, we used Multiple Convolutional Neural Networks to detect the abnormal problem using chest X-ray images [8]. X-ray images are most used to identify heart diseases. Understanding of chest radiographs for doctors is one of the crucial and deciding factors to detect the different diseases like fibrosis, heart, tuberculosis, and many other diseases, also it is a time-consuming and challenging task for the medical field. Hence computer techniques are used to get accurate results. In this paper, we implemented Deep Convolutional Neural Network to classification the chest X-ray into 14 different diseases with ensuring accurate diagnosis [9]. III. DATASET USED NIH Chest X-ray dataset consists of 112,120 frontal view x-ray images in the PNG format. Each image contains 14 different thorax disease labels (absent or present) and a data enquiry CSV file from 30,805 unique patients. This dataset is taken from the Kaggle repository. Link: https://www.kaggle.com/nih-chest-xrays/data REFERENCES [1] [2] [3] [4] [5] [6] [7] [8] [9] L. Luo et al., “Deep Mining External Imperfect Data for Chest X-ray Disease Screening,” vol. 0062, no. c, pp. 1–12, 2020, doi: 10.1109/TMI.2020.3000949. A. Prasoon, K. Petersen, C. Igel, F. Lauze, E. Dam and M. Nielsen, "Deep feature learning for knee cartilage segmentation using a triplanar convolutional neural network", Medical Image Computing and Computer-Assisted Intervention-M1CCAI Springer Berlin Heidelberg, pp. 246-253, 2013. J. Wu et al., “Automatic Bounding Box Annotation of Chest X-Ray Data for Localization of Abnormalities,” Proc. - Int. Symp. Biomed. Imaging, vol. 2020-April, pp. 799–803, 2020, doi: 10.1109/ISBI45749.2020.9098482. WYN Naing, ZZ Htike, "ADVANCES IN AUTOMATIC TUBERCULOSIS DETECTION IN CHEST X-RAY IMAGES", 2014 - academia.edu D. C. Ciresan, A. Giusti, L. M. Gambardella and J. Schmidhuber, "Mitosis detection in breast cancer histology images with deep neural networks", Medical Image Computing and Computer-Assisted Intervention-MICCAI Springer Berlin Heidelberg, pp. 411-418, 2013. Kesim, E., Dokur, Z., & Olmez, T. (2019). X-Ray Chest Image Classification by A Small-Sized Convolutional Neural Network. 2019 Scientific Meeting on Electrical-Electronics & Biomedical Engineering and Computer Science (EBBT). K. Wang, X. Zhang, and S. Huang, “KGZNet:Knowledge-Guided Deep Zoom Neural Networks for Thoracic Disease Classification,” Proc. 2019 IEEE Int. Conf. Bioinforma. Biomed. BIBM 2019, pp. 1396–1401, 2019, doi: 10.1109/BIBM47256.2019.8982943. Kieu, P. N., Tran, H. S., Le, T. H., Le, T., & Nguyen, T. T. (2018). Applying Multi-CNNs model for detecting abnormal problem on chest x-ray images. 2018 10th International Conference on Knowledge and Systems Engineering (KSE). Siamak, A., Sadeghian, R., Abdellatif, I., & Nwoji, S. (2019). Diagnosing Heart Disease Types from Chest X-Rays Using a Deep Learning Approach. 2019 International Conference on Computational Science and Computational Intelligence (CSCI).