Plasmodium falciparum Insecticide-treated nets (ITNs) Rings of P. falciparum in a thin blood smear. Thin and delicate Possess one or two chromatin dots. Ring-form trophozoites in thin blood smears Exhibiting Maurer's clefts Gametocytes in a thick blood smear. Crescent- or sausage-shaped Schizonts in thin blood smear. Contain anywhere from 8-24 merozoites Microscopy Molecular Diagnosis Antigen Detection Intermittent preventive treatment of malaria in pregnant women (IPTp) Intermittent preventive treatment of malaria in infancy (IPTi) Indoor residual spraying (IRS) https://www.cdc.gov/dpdx/malaria/index.html https://www.sciencedirect.com/science/articl e/abs/pii/S1471492218302484 Quinine-based therapy is with quinine (or quinidine) sulfate plus doxycycline or clindamycin or pyrimethamine-sulfadoxine