Cell Biology: MITOSIS: • • • • Occurs in all body cells In such cells there are 2 sets of each chromosome – one maternal and one paternal – 2n In total there are 46 chromosomes and there can only ever be 46 chromosomes* In a cell that has replicated there will be 92 chromatids – still only 46 chromosomes STAGES OF MITOSIS: Interphase: Majority of the time a cell cycle the cell is in interphase. • • • DNA replication Protein synthesis Carrying out cellular functions Prophase: This is the beginning of mitosis. • • • • The nuclear membrane begins to disappear The chromatins (genetic material) begin to condense The centrioles move to the poles The nucleolus disappears Metaphase: This is when the nucleus is beginning to divide • • • The chromosomes line up in the centre of the cell along the equator The spindle fibres attach to the centromere The centrioles are at the poles of the cell Anaphase: This is the direct spilt of the chromatids • • • The spindle fibres contract The sister chromatids full away from each other There are now 92 chromosomes – 46 at each pole Telophase: The final part of mitosis • • The nuclear membrane reforms around the now separate chromatids The chromosomes diffuse and become less compact