Did you Know? Agarose gel electrophoresis is a method of gel electrophoresis used in biochemistry, molecular biology, genetics, and clinical chemistry to separat e a mixed population of macromolecules such as DNA or proteins in a matrix of agarose. Applications: 1. Estimation of the size of DNA molecules. 2. Analysis of products of a polymerase chain reaction (PCR), e.g. in molecular genetic diagnosis or genetic fingerprinting. 3. Separation of DNA fragments for extraction and purification. 4. Separation of proteins, for example, screening of protein abnormalities in clinical chemistry.