ACTIVE LEARNING TEMPLATE: Medication STUDENT NAME _____________________________________ Norvasc (amlodipine) MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________ channel blockers CATEGORY CLASS antihypertensives/calcium ______________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action Inhibits the transport of calcium into myocardial and vascular smooth muscle cells, resulting in inhibition of excitation-contraction coupling and subsequent contraction. Therapeutic Use Systemic vasodilation resulting in decreased BP. Coronary vasodilation resulting in decreased frequency and severity of attacks of angina. Complications peripheral edema Medication Administration PO Contraindications/Precautions Hypersensitivity; Systolic BP <90 mm Hg. Nursing Interventions Ineffective tissue perfusion Acute pain Interactions Strong CYP3A4 inhibitors, including ketoconazole, itraconazole, clarithromycin, and ritonavir may ↑ levels. Client Education Evaluation of Medication Effectiveness Decrease in BP. Decrease in frequency and severity of anginal attacks. Decrease in need for nitrate therapy. Increase in activity tolerance and sense of well-being ACTIVE LEARNING TEMPLATES Advise patient to take medication as directed, even if feeling well. Take missed doses as soon as possible within 12 hrs of missed dose. THERAPEUTIC PROCEDURE A7