Understanding Enablers and Processes of Entrepreneurial Resourcefulness and Social Innovation in Informal Economic Space Entrepreneurial Resourcefulness, an entrepreneur’s capacity to engage with their limited resource base is central in adapting to various contextual constraints. While social innovation focuses on initiatives that meet societal needs with the aim of contributing to empowerment and social change. We believe that there is a lot common in resourcefulness and social innovation practices as both aim to empowerment and resilience against contextual constraints. With this understanding we aim to link and understand these both phenomenon of entrepreneurial; resourcefulness and social innovation in this study. This book chapter aims to understand the economic foundations of resourcefulness and social innovation, with a focus on how resourceful informal economic activities can change the lives of marginalized and disempowered citizens in society. Through qualitative in-depth interviews this study explores the triggers and activities of entrepreneurial resourcefulness in facilitating social innovation in informal economic markets in Pakistan. Comparing 15 cases, main enablers for altering social empowerment issues are identified as information seeking, diversity in mobilized resources, collaborations, entrepreneurial readiness have been identified. This research highlights two important characteristics of resourcefulness as a) local mobilization of resources and b) collective nature of resourcefulness practices. In light of these insights this research contributes to understanding resourcefulness as a contextual phenomenon that foregrounds in collective local practices.