MICROBIOLOGY AND PARASITOLOGY (BIOL 115) Berna Lou Aba-Regis Instructor MICROBIOLOGY: INTRODUCTION • Microbiology is the study of microorganisms; a large and diverse group of microscopic organisms that exist as single cells or cell clusters; it also includes viruses, which are microscopic but not cellular MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • They are responsible for cycling the chemical elements essential for life, including carbon, nitrogen, sulfur, hydrogen, and oxygen; MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • more photosynthesis is carried out by microorganisms than by green plants. • There are 100 million times as many bacteria in the oceans (13 × 10 28 ) as there are stars in the known universe. MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • It has been estimated that 5x1030 microbial cells exist on earth; excluding cellulose, these cells constitute about 90% of the biomass of the entire biosphere. • Humans also have an intimate relationship with microorganisms; more than 90% of the cells in our bodies are microbes. MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • The bacteria present in the average human gut weigh about 1 kg, and a human adult will excrete his or her own weight in fecal bacteria each year. MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • Microorganisms are host to viruses and are infected by them • They are found almost everywhere in the planet except on highly sterile sites MICROBIOLOGY: INTRODUCTION • They exist as normal microbiota to plants animals and humans, as well as the opportunistic and pathogenic groups • Normal microbiota or microflora- harmless and mostly beneficial to the host • Opportunistic microbiota- Can cause disease when condition for infection is favourable • Pathogenic microbiota- Disease causing MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • Microbes are used for understanding cellular functions and many other cell and molecular biology researches; including biochemistry and biophysics MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • They are being explored for many medical applications and pharmaceutical potentials MICROBIOLOGY: INTRODUCTION • Impact of microorganisms: • They are also used widely in the food and beverage industry and other material industry applications and agriculture, bioremediation, cosmetics, artistry, etc. • Microbes are small with tremendous impact to our planet and our existence as a whole Fields of Microbiology Microbiology Basic Microbiology Bacteriology Phycology Mycology Protozoology Parasitology Virology By process Microbial In relation metabolism Immunology Microbial genetics Epidemiology Microbial ecology Disease-related Environment to disease Etiology Infection Control Chemotherapy Environmental morphology Microbial Taxonomy By kind of organism Applied Microbiology Industry Food and beverage technology Pharmaceutical microbiology Genetic engineering Organisms included in the study of Microbiology 1. Bacteria- Bacteriology 2. Protozoans- Protozoology 3. Algae- Phycology 4. Parasites- Parasitology 5. Yeasts and Molds, Fungi - Mycology 6. Viruses- Virology Bacteria and Parasites are Prokaryotes PROKARYOTES Other distinguishing characteristics of the prokaryotes are: • Small size, usually on the order of 1 μm in diameter, • The DNA of almost all bacteria is a circle with a length of about 1 mm; the prokaryotic chromosome. • The chromosomal DNA must be folded more than 1000-fold just to fit within the prokaryotic cell membrane. • The small size of the prokaryotic chromosome limits the amount of genetic information it can contain. • Any one prokaryote carries relatively few genes that allow physiologic accommodation of the organism to its environment. • The range of potential prokaryotic environments is unimaginably broad. • The range of prokaryotic niches is illustrated by consideration of strategies used for generation of metabolic energy.