Publications
1. Nicholson, N., M. Irwin and G.R. Poirier (1982). Immunofluorescent localization of a
seminal vesicle proteinase inhibitor in the female reproductive tract of naturally
inseminated mice. J Exp Zool 225:481-487.
2. Irwin, M., N. Nicholson, J.T. Haywood and G.R. Poirier (1983). Immunofluorescent
localization of a murine seminal vesicle proteinase inhibitor. Biol Reprod 28:1201-1206.
3. Mayne, R., H. Wiedemann, M.H. Irwin, R.D. Sanderson, J.M. Fitch, T.F. Linsenmayer
and K. Kuhn (1984). Monoclonal antibodies against chicken type IV and V collagens:
Electron microscopic mapping of the epitopes after rotary shadowing. J Cell Biol
98:1637-1644.
4. Irwin, M.H., S.H. Silvers and R. Mayne (1985). Monoclonal antibody against chicken
type IX collagen: Preparation, characterization and recognition of the intact form of type
IX collagen secreted by chondrocytes. J Cell Biol 101:814-823.
5. Mayne, R. and M.H. Irwin (1986). "Collagen Types in Cartilage". In: Articular Cartilage
Biochemistry, K.E. Kuettner, R. Schleyerbach and V.C. Hascall, Editors. Raven Press,
New York. pp. 23-28.
6. Irwin, M.H. and R. Mayne (1986). Use of monoclonal antibodies to locate the chondroitin
sulfate chain(s) in type IX collagen. J Biol Chem 261:16281-16283.
7. Linsenmayer, T.F., A. Mentzer, M.H. Irwin, N.K. Waldrep and R. Mayne (1986). Avian
type VI collagen: Monoclonal antibody production and immunohistochemical
identification as a major connective tissue component of cornea and skeletal muscle.
Exp Cell Res 165:518-529.
8. Summers, T., M.H. Irwin, R. Mayne and G. Balian (1988). Monoclonal antibodies to
type X collagen. Biosynthetic studies using an antibody to the amino-terminal domain. J
Biol Chem 263:581-587.
9. Vaughan, L., M. Mendler, S. Huber, P. Bruckner, K.H. Winterhalter, M.H. Irwin and R.
Mayne (1988). D-periodic distribution of collagen type IX along cartilage fibrils. J Cell
Biol 106:991-997.
10. Mayne, R., S. Swasdison, R.D. Sanderson and M.H. Irwin (1989). "Extracellular Matrix,
Fibroblasts and the Development of Skeletal Muscle". In: Cellular and Molecular Biology
of Muscle Development, F. Stockdale and L. Kedes, Editors. UCLA Symposium on
Molecular and Cellular Biology. Alan R. Liss, New York, Vol. 93. pp. 107-116.
11. Abrahamson, D.R., M.H. Irwin, P.L. St. John, E.W. Perry, M.A. Accavitti, L.W. Heck and
J.R. Couchman (1989). Selective immunoreactivities of kidney basement membranes to
monoclonal antibodies against laminin: Localization of the end of the long arm and the
short arms to discrete microdomains. J Cell Biol 109:3477-3491.
12. Shimokomaki, M., D.W. Wright, M.H. Irwin, M. van der Rest and R. Mayne (1990). "The
structure and macromolecular organization of type IX collagen in cartilage." In: Structure,
Molecular Biology, and Pathology of Collagen, R. Fleischmajer, B.R. Olsen, & K. Kühn,
editors. Annals of the New York Acad Sci Vol 580, pp. 1-7.
13. Heck, L.W., W.D. Blackburn, M.H. Irwin and D.R. Abrahamson (1990). Degradation of
basement membrane laminin by human neutrophil elastase and cathepsin G. Amer J
Pathol 136:1267-1274.
14. Geisert, E.E. Jr., T.P. Murphy, M.H. Irwin and H. Larjava (1991). A novel cell adhesion
molecule, G-CAM, found on cultured rat glia. Neurosci Lett 133:262-266.
15. Steadman, R., M.H. Irwin, P.L. St. John, W.D. Blackburn, L.W. Heck and D.R.
Abrahamson (1993). Laminin cleavage by activated human neutrophils yields proteolytic
fragments with selective migratory properties. J Leukocyte Biol 53:354-365.
16. Irwin, M.H. and E.E. Geisert, Jr. (1993). The upregulation of a glial cell surface antigen
at the astrocytic scar in the rat. Neurosci Lett 154:57-60.
17. Peduzzi, J.D., M.H. Irwin and E.E. Geisert, Jr. (1994). Distribution and characteristics of
a 90 kDa protein, KG-CAM, in the rat CNS. Brain Res 640:296-307.
18. Pinkert, C.A., M.H. Irwin and R.J. Moffatt (1995). Transgenic animal modeling. In: R.A.
Meyers (Ed.) Molecular Biology and Biotechnology. pp. 901-907, VCH, New York.
19. Geisert, E.E., L. Yang and M.H. Irwin (1996). Astrocyte growth, reactivity and the target
of the antiproliferative antibody, TAPA. J Neuroscience 16:5478-5487.
20. Irwin, M.H., R.J. Moffatt and C.A. Pinkert (1996). Identification of transgenic mice by
PCR analysis of saliva. Nature Biotechnol 14:1146-1149.
21. Pinkert, C.A., M.H. Irwin and R.J. Moffatt (1997). Transgenic animal technology. In: R.A.
Meyers (Ed.) Encyclopedia of Molecular Biology and Molecular Medicine Vol 6. pp. 6374, VCH, New York.
22. Vergara, G.J., M.H. Irwin, R.J. Moffatt and C.A. Pinkert (1997). In vitro fertilization in
mice: strain differences in response to superovulation protocols and effect of cumulus
cell removal. Theriogenology 47:1245-1252.
23. Pinkert, C.A., M.H. Irwin and R.J. Moffatt (1997). Transgenic animal modeling. In: R.A.
Meyers (Ed.) Encyclopedia of Molecular Biology and Molecular Medicine. Volume 6, pp.
63-74, VCH, New York.
24. Pinkert, C.A., M.H. Irwin, L.W. Johnson and R.J. Moffatt (1997). Mitochondria transfer
into mouse ova by microinjection. Transgenic Res 6:379-383.
25. Irwin, M.H., L.W. Johnson and C.A. Pinkert (1999). Isolation and microinjection of
somatic cell-derived mitochondria and germline heteroplasmy in transmitochondrial
mice. Transgenic Res 8:119-123.
26. Pinkert, C.A., L.W. Johnson, M.H. Irwin, S. Wong, E.E. Baetge, D.F. Wolfe, S.A.
Simpkins, W.F. Owsley and F.F. Bartol (2001). Optimization of superovulation and
fertilization protocols in the production of transgenic swine. Adv Reprod 5:45-53.
27. Irwin, M.H., V. Parrino and C.A. Pinkert (2001). Construction of a mutated mtDNA
genome and transfection into isolated mitochondria by electroporation. Adv Reprod 5:5966.
28. Irwin, M.H., W.K. Pogozelski and C.A. Pinkert (2002). PCR optimization for detection of
transgene integration. In: C.A. Pinkert (Ed.) Transgenic Animal Technology: A
Laboratory Handbook. 2nd ed., pp. 475-484. Academic Press, San Diego.
29. Pinkert, C.A., M.H. Irwin and R.L. Howell (2004). Animal biotechnology and modeling.
In: R.A. Meyers (Ed.) Encyclopedia of Molecular Cell Biology and Molecular Medicine.
Vol. 1, pp. 209-240. Wiley-VCH, Weinheim.
30. Shi, J., M.H. Irwin and C.A. Pinkert (2008). Mitochondria transfer into fibroblasts:
Liposome-mediated transfer of labeled mitochondria into cultured cells. Ethnicity
Disease 18:S1-43-44.
31. Parameshwaran, K., M.H. Irwin, K. Steliou and C.A. Pinkert (2010). D-Galactose
effectiveness in modeling aging and therapeutic antioxidant treatment in mice Rejuv Res
13(6):729-735.
32. Cannon, M.V., D.A. Dunn, M.H. Irwin, A.I. Brooks, F.F. Bartol, I.A. Trounce and C.A.
Pinkert (2011). Xenomitochondrial mice: investigation into mitochondrial compensatory
mechanisms. Mitochondrion 11(1):33-39
33. Dunn, D.A., M.V. Cannon, M.H. Irwin and C.A. Pinkert (2012) Animal models of human
mitochondrial DNA mutations. Biochim Biophys Acta 1820(5):601-607.
34. Parameshwaran, K., M.H. Irwin, K. Steliou and C.A. Pinkert (2012). D-Galactose,
dietary sugars and modeling neurological aging. In: Preedy. V.R.(Ed.) Food and
Nutritional Components in Focus. Royal Society of Chemistry 3:670-687.
35. Parameshwaran, K, M.H. Irwin, K. Steliou and C.A. Pinkert (2012). Protection by an
antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation
and cellular stress in mouse brain. Pharmacol Biochem Behavior 101(3):487-492.
36. Shi, J., M.H. Irwin and C.A. Pinkert (2012). Liposome-mediated transfer of mitochondria
harboring foreign mitochondrial DNA into cultured fibroblasts. AU J Undergrad Res 1:811.
37. Irwin, M.H., K. Parameshwaran and C.A. Pinkert (2013). Mouse models of mitochondrial
complex I dysfunction. Int J Biochem Cell Biol 45:34-40.
38. Su B., M. Shang, R. Thresher, P. Grewe, J. Patil, E. Peatman, M.H. Irwin, C. Pinkert, Q.
Cheng, D. Perera, C.-C. Weng, C. Li, M. Fobes, R. Beam, H. Li, J. Zhanga and R.
Dunham (2014). Expression and Knockdown of Primordial Germ Cell Genes, Vasa,
Nanos and Dead end in Common Carp, Cyprinus carpio, Embryos for Transgenic
Sterilization and Reduced Sexual Maturity. Aquaculture 420-421:S72-S84.
39. Irwin, M.H., W. Pogozelski and C.A. Pinkert (2014). PCR Optimization for analysis of
transgene integration. In: Pinkert, C.A. (Ed.) Transgenic Animal Technology: A
Laboratory Handbook. 3rd ed., pp. 533-541. Elsevier, London.
40. Irwin, M.H. and C.A. Pinkert (2014). Analysis of transgene expression. In: Pinkert, C.A.
(Ed.) Transgenic Animal Technology: A Laboratory Handbook. 3rd ed., pp. 543-564.
Elsevier, London.
41. Pinkert, C.A., M.H. Irwin, K. Takeda and I.A. Trounce (2014). Modifying mitochondrial
genetics. In: Pinkert, C.A. (Ed.) Transgenic Animal Technology: A Laboratory Handbook.
3rd ed., pp. 639-656. Elsevier, London.
42. Cannon, M.V., M.H. Irwin, M.C. Kohn, T.D. Brandebourg, D. Đikić and C.A. Pinkert
(2015). Mitochondrial DNA sequence and phylogenetic evaluation of geographically
disparate Sus scrofa breeds. Anim Biotechnol 26:17-28. PMID: 25153451.
43. Su, B., M. Shang, C. Li, D. Perera, C.A. Pinkert, M.H. Irwin, E. Peatman and R.A.
Dunham (2015) Effects of transgenic sterilization constructs and their repressor
compounds on hatch, developmental rate and early survival of electroporated channel
catfish embryos and fry. Transgenic Res 24:333-352.
44. Cannon, M.V., M.H. Irwin and C.A. Pinkert (2015). Mitochondrially-imported RNA in
drug discovery. Drug Dev Res 76:61-71.
45. Parameshwaran, K., M.H. Irwin, K. Steliou, V. Suppiramaniam and C.A. Pinkert (2015).
Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I
inhibition. Drug Dev Res 76:72-81.
46. Steliou, K., D.V. Faller, C.A. Pinkert, M.H. Irwin and W.H. Moos (2015). Bioprotective
Carnitinoids: Lipoic Acid, Butyrate, and Mitochondria-Targeting to Treat Radiation Injury.
Drug Dev Res in press.