Five in One: An Innovation That Combines Several Diagnostic Strategies Pentacam – The World’s First 3 D-Scheimpflug Camera F or any ophthalmologist who considers buying a new device for his private surgery or clinic, the cost-benefit ratio of such an investment is of primary importance. Besides asking “What is this instrument able to do what others can’t” there is – for most doctors – the space issue: “Do I have room for another unit?”. It is a compact instrument which combines several diagnostic strategies and promises to fulfill the highest clinical, as well as practical demands, and to fit in a very restrictive budget. A symposium at the 17th Congress of Germany’s ophthalmic surgeons in Nuremberg left the audience with the impression that such a device is now available: the Pentacam, the world’s first three-dimensional rotating Scheimpflug camera. This most intriguing innovation was presented by experts like O. Kermani (Cologne), T. Neuhann (Munich) and O. Schneider (Wetzlar). The most striking feature of the Pentacam is that it is much more modules which analyze and interpret the tasks performed: Scheimpflug picture, pachymetry, densitometry, corneal topography, 3-D chamber analysis and tomography. The data acquired is extremely useful for a number of ophthalmological indications: refractive surgery, glaucoma, cataract and pathological conditions of the cornea like keratoconus. Oculus Pentacam: Complete diagnosis of the anterior ocular segments than just a camera. It is a diagnostic unit able to perform a host of different measurements and analyses on the anterior segment of the eye. Using an automatic rotating camera, this innovation examines the anterior segment without ever touching the eye. The examination takes approximately two seconds, time enough to take about 50 pictures of the eye’s different anatomical layers. There are several different 3-D analysis of the anterior chamber helps to assess the risk of glaucoma Scheimpflug pictures can be taken as a series of single exposures from different angles as well as a 3-D scan. The 3-D analysis presents the different layers (anterior corneal segment, the cornea’s posterior layer, iris and lens) in an easily recognizable way. In addition, the Pentacam automatically measures the anterior chamber angle, chamber volume, chamber depth, cor- Pentacam neal eccentricity, pupillary diameter, the cornea’s central radius and corneal astigmatism at the same time. Pictures taken as a 3-D scan can be analyzed individually. According to O. Kermani, there is no significant difference between Pentacam´s pachymetric results and those of comparable (though exclusively pachymetric) instruments already on the market. The same applies if the Pentacam’s keratometry is compared to that of devices already in use. An additional, and sometimes crucial benefit is measuring the anterior chamber depth. This gives the ophthalmologist a realistic idea of how seriously his patient may be threatened by glaucoma. That knowledge can be decisive in the preoperative planning of corneal or lens surgery which might lead to a (further) shallowing of the chamber. T. Neuhann made it quite clear if the surgeon has to deal with a chamber depth of less than 2 millimeters, a prophylactic YAG iridotomy should be performed as an efficient way to prevent angle closure. Measuring the cornea’s thickness helps to evaluate the “true” IOP Glaucoma is in the literal crosshairs of another examination, measurement of the corneal thickness, which in some European countries like Germany has gained wide acceptance among the population. It is known that measuring the intraocular pressure (IOP) using a Goldmann is not the only test in glaucoma diagnostics. Intra-ocular pressure alone is only one of several factors that determine the existence of glaucoma. This decision requires a careful examination of the optic disc. But the IOP measured by tonometry might not be exactly the pressure that actually exists The cornea’s thickness is displayed for the whole surface from limbus to limbus. 2 inside the eye. The reason for this confusion, corneal thickness influences the results of tonometry to a sometimes significant degree. If the patient’s cornea matches exactly the statistically “normal” thickness of 550 µm, the IOP measured is indeed the IOP that keeps the eye in shape or, in glaucoma, threatens to damage the neuronal axons. If the cornea is thinner, however, it is easier for Goldmann’s device to flatten its surface – the result is an IOP reading which is unrealistically low. A result might give both the doctor and his or her patient an undue sense of security – the threat of glaucoma hides behind a false interpretation of Goldmann’s tonometry. The opposite can happen with a cornea of above-normal thickness: an “increased” IOP will be measured which might lead to glaucoma therapy that – given the real, lower IOP – comes too early or is too intense. How Pentacam portrays a case of cataracta coronaria. OPHTHALMO-CHIRURGIE SPECIAL EDITION NOVEMBER 2004 Pentacam Using Pentacam’s pachymetric abilities puts these data into its proper place again. If the ophthalmologist knows the exact corneal thickness, calculating the real IOP with some formulas is no problem at all. One of these formulas to determine the IOP, after having measured corneal thickness, has been developed by Professor Lutz Pillunat and his team at the University Eye Hospital in Dresden. Using it on patients with an extremely thin or an extremely thick cornea gives you an idea of how misleading tonometry can become. A cornea that is only 450 µm thick may have an IOP that is no less than 4,0 mm below the real thing – and in daily ophthalmological practice, it makes a difference whether a patient’s intra-ocular pressure is 20 mm Hg or 24 mm Hg. A difference like this may be important to decide between initiating treatment and a waitand-see attitude. In dealing with a thick cornea, the IOP has to be adjusted to a lower value. If, for example, the Pentacam detects a corneal thickness of 630 µm in a patient, according to the Dresden formula 3,20 mm Hg has to be taken away from the IOP measured with Goldmann’s tonometry. Refractive surgery without knowing corneal thickness? Never ! Pachymetry provided by Pentacam not only plays a major role in glaucoma diagnostics, but also in the pre- and postoperative care of patients undergoing refractive sur- gery T. Neuhann has pointed out – to know the exact location of the cornea’s thinnest spot. The Pentacam’s keratometry gives the ophthalmic surgeon an excellent overview of the patient’s corneal topography and puts him or her in a position to operate even in areas with a relatively thin stroma while keeping the necessary safety distance. A postoperative assessment of the flap is easily done and doesn’t bother the patient at all. The most important features of this examination are • automatic initiation of the measurement, • a high reproducibility, • non-contact measuring, • less than two seconds required. Pentacam’s pachymetry provides data from one limbus to the other. Densitometry of the lens: a great tool for the long-term control of cataracts The cataract surgeon enjoys the same benefits by relying on a preoperative scan done with Pentacam. Pentacam’s densitometry of the human lens provides the ophthalmologist with an analysis of the lens thickness and of structural alterations like radial opacities and early or advanced calcification of the lens core. Densitometry comes with advantages: • the evolution of a cataract can be made visible even at an early stage, • it makes classification of the cataract easy, • long-term controls of cataracts are possible and OPHTHALMO-CHIRURGIE SPECIAL EDITION NOVEMBER 2004 • the extension of the cataract can be measured. Knowing the thickness of the lens is helpful for the ophthalmic surgeon in deciding which type of IOL (intra ocular lens) to use for implantation. Furthermore, it hints – together with data on the anterior chamber’s depth – to possible causes for postoperative trouble. Hyperopic eyes which are relatively short sometimes are a major cause for concern. In the event of angle reduction they tend to react with a postoperative IOP increase. They also have a higher risk to develop a macular degeneration following phacoemulsification (or to worsen if macular degeneration already exists at the time of cataract surgery). Assessing the anterior chamber’s depth map is also possible when using Artisan intraocular lenses, a task that, according to O. Kermani, both OrbScan II and IOL-Master can not perform. Examination by Pentacam is both efficient and fast... Using Pentacam in your daily surgery is both easy and time-saving. According to O. Schneider the instrument takes about 50 Scheimpflug pictures within just two seconds and can deliver up to 25.000 true elevation points of topographical information when measuring corneal topography. Due to the high amount of data collected there usually is enough information to come to a reasonable diagnosis. Even situations traditionally considered artifacts like a narrow lid margin or shadow zones can’t 3 Pentacam prevent the Pentacam from producing sufficient Scheimpflug pictures for clinical assessment ...and makes it easy for the patient to see his doctor again An examination is absolutely pain-free and is done within the shortest time span it’s most likely to become a favorite with the patients and thus strengthens the patient-doctor relationship. Everything with Pentacam happens in a non-contact way which reassures even the most timid patient. It is also an educational tool because a printout of his or her own clinical picture as captured by Pentacam can be handed over to the patient. It is quite an impressive document. T. Neuhann compares its psychological impact on the patient with the sonographic picture of a baby in utero that usually is a source of joy to any expecting mother (and father).The price for such an extensive clinical examination currently is about 75 Euro. The fact that operating Pentacam can be delegated to the practice’s person- Cataracta pulverulenta, as seen by Pentacam. OPHTHALMO-CHIRURGIESpecial Edition in collaboration with Oculus Optikgeräte GmbH, Münchholzhäuser Straße 29, 35582 Wetzlar, Germany 4 nel also contributes to its economic efficiency. Analyzing the results and discussing them with the patient should be done only by the ophthalmologist. Neuhann’s conclusion: the Pentacam is a diagnostic tool which helps all ophthalmologists. With its ability to focus on several aspects like diagnosing glaucoma, preparing for cataract surgery, the pre-operative planning and follow-up of refractive surgery and the evaluation of keratoconus it enables the ophthalmologist to get an excellent overview of everything that matters in the anterior segment of the eye. 3 D Tomography of the eyes’ anterior segment. Editor: KIM – Kommunikation in der Medizin Author: Dr. med. Ronald D. Gerste Project manager: Dr. med. S. Kaden Dr. R. Kaden Verlag GmbH & Co. KG Ringstraße 19b 69115 Heidelberg Germany OPHTHALMO-CHIRURGIE SPECIAL EDITION NOVEMBER 2004