Syllabus - CELL 2050-01 Genetics Spring 2014 – Tulane University Instructor: Dr. Meenakshi Vijayaraghavan email: mviji@tulane.edu Class Schedule: MWF 12.00 – 12.50PM, Richardson 117 Office Hours: MW 1.15- 2.30PM Office: 4006 Percival Stern Hall Course Information and Learning Objectives Catalog Description: The principles of genetic analysis and the nature of genes, discussion of DNA, chromosomes, and molecular mechanism of replication, mutation, expression, and transmission of heritable characteristics. Course Objectives: Students are expected to have a firm understanding of the gene, protein synthesis, Mendelian and non- Mendelian inheritance patterns, linkage analysis and microbial genetics. General Course Description: This course includes a study of basic concepts of classical and molecular genetics and application of genetic principles to biological problems. Course Learning Outcomes: At the completion of the course, students will be able to describe Mendelian inheritance describe the structure of chromosome, DNA, and RNA describe DNA replication and protein synthesis describe the relationship between genes and traits recognize and explain the patterns of inheritance solve problems related to probability apply and appreciate genetic concepts Pre- requisites: Introduction to (CELL 1010) Textbook: Grading: Genetics: Analysis and Principles (4th edition) by Robert J.Brooker Published by McGraw-Hill Home work Three midterm exams at 20% each Comprehensive final examination Final grade Extra credit work will not be assigned. 10% 60% 30% ____ 100% Attendance, Homework, and Reading: Attendance will be taken; if you miss too many classes (>3) your grade will be reduced one level (E.g. A to A-) as will be the case when you use cell phones to receive or send voice or text messages. Tardiness in class is not tolerated as is leaving early during the lecture. Home work will be posted in the BB, and/or Connect, and/or given as handouts in class, details of which are given in the BB. Failure to complete will affect the final grade for this class. Syllabus and class schedule are posted on the Blackboard website – http://mytulane.blackboard.com. The tentative lecture topics and assigned textbook readings are given below. Tentative Class Schedule – MWF (12 - 12:50PM) Date January 13 15 17 20 Topic Overview Mendel’s Laws of Inheritance Chap.2, Extensions of Mendelian Inheritance Martin L King Holiday Reading Chapter 1 Chapter 2 Chapters 2,4 1 22 24 27 29 31 February 3 5 7 10 12 14 17 19 21 24 26 28 March 3-7 10 12 14 17 19 21 24 26 28 31 April 2 4 7 9 11 14 16 18- 21 23 25 28 May 3 Extensions of Mendelian Inheritance Contd. Non-Mendelian Inheritance Non-Mendelian Inheritance Non-Mendelian Inheritance Chapter 4 Chapter 4 Chapter 5 Chapter 5 Chapter 5 Non-Mendelian Inheritance Reproduction and Chromosome Transmission Reproduction and Chromosome Transmission EXAM - I Reproduction and Chromosome Transmission Chromosome Organization Molecular Structure Variation in Chromosome Structure and Number Variation in Chromosome Structure and Number Variation in Chromosome Structure and Number Genetic Linkage Mapping in Eukaryotes Chapter 5 Chapter 3 Chapter 3 Mardi Gras/Spring Break Molecular Structure of DNA and RNA DNA Replication Replication Contd. EXAM - II Gene Transcription Contd. Contd. RNA Modification Translation Translation Contd. Gene Regulation in Bacteria Contd. Gene Regulation in Eukaryotes Gene Regulation in Eukaryotes Gene Regulation in Eukaryotes Gene Mutation and DNA Repair Easter Break Exam - III Gene Mutation and DNA Repair Population Genetics Chapter 3 Chapter 10 Chapter 10 Chapter 8 Chapter 8 Chapter 8 Chapter 6.1 Chapter 6.1 Chapter 9 Chapter 11 Chapter 11 Chapter 12 Chapter 12 Chapter 12 Chapter 12 Chapter 13 Chapter 13 Chapter 13 Chapter 14.1 Chapter 14.2 Chapter 15 Chapter 15 Chapter 15 Chapter 16 Chapter 16 Chapter 24.1 Final Exam- 1- 3 PM Missed Exam: All exams are expected to be taken at the scheduled date and time with the section you are registered in. Score in a missed exam will be recorded as zero. No make-up exam will be given. Any make-up request for students in case of emergencies should be made the day before the exam and not after the exam. This make-up request also requires a written excuse to be submitted to and approved by the Dean. If a make-up is given, it will not include multiple –choice format. No student will be allowed to take the final exam with another section and such requests will NOT be granted. Tulane Honor Code: Students are expected to adhere to the principles of the Tulane Honor Code at all times. Any violations of this code will not be tolerated. The Honor Code can be found online - http://studentaffairs.tulane.edu/Judicial/CodeofStudentConduct.pdf. 2