Conclusions and implications This paper adopts the well-established TAM and D&M model to measure the impact of information system on knowledge sharing and CRM. This study provides a theoretical framework for determining the impact of information technology system to knowledge sharing among employees which is more likely to influence the CRM. We use a structural equation model to test the framework. The results ofour study indicated that the proposed metrics have an high degree of validity and reliability. The analysis provides a reliable measurement for setting up key constructs in the study of knowledge sharing and customer relationship management.