Molt-inhibiting hormone (MIH)
生物技術概論(高立圖書)
第十章
10-1
The blue crab is abundant in the Gulf of
Mexico, and soft-shelled crabs are
considered a delicacy by seafood
lovers. However, the soft crab industry of
the Gulf states is limited by a supply of
freshly molted crabs that is both seasonal
and unpredictable. These researchers are
developing a technique for manipulating
the blue crab molting cycle that will allow
suppliers to provide an abundant and
controllable supply of soft-shelled crabs.
The researchers will build on their previous work in which they cloned a cDNA
encoding molt-inhibiting hormone (MIH). It is generally accepted that MIH inhibits the
endocrine glands, the Y-organs, during much of the molting cycle, and a molting
sequence is initiated when MIH secretion diminishes or stops. The experiments will
include the use of recombinant MIH and other compounds with similar chemical
structures to identify inhibitors of MIH. In addition, the researchers will apply recent
innovations to screen and isolate peptide inhibitors of MIH. Selected peptide inhibitors
will be tested for their effectiveness at controlling the molt cycle by blocking MIH
activity.
生物技術概論(高立圖書)
第十章
10-2
生物技術概論(高立圖書)
第十章
10-3