Cardiovascular Disease Caused by • Atherosclerosis – Blocked artery • By plaque • Arteriosclerosis – “Hardening of the arteries” Coronary Artery Disease • Plaque buildup in arteries of the heart • No outward symptoms • Can produce a myocardial infarction – Heart attack – Due to blocked artery Stroke • Third most frequent cause of death • Blocked artery in the brain • Due to – arteriosclerosis – arteriosclerosis • Common stroke – Blocked artery • Hemorrhagic stroke – Burst blood vessel Hypertension • Abnormally high blood pressure • Best predictor of heart attack and stroke Declining death rates in cardiovascular disease • Due to: – Better diet – Reduction in cigarette smoking – Improved emergency care Framingham Heart Study • Risk factors for heart disease – Cigarette smoking – High cholesterol – Hypertension – Sedentary lifestyle – Obesity Framingham Heart Study • LDL - Low-density lipoprotein – Positively related to cardiovascular disease – “L” = Lousy • High-density lipoprotein – Protection against heart disease Cholesterol • Total cholesterol – = LDL + HDL + Triglycerides • Ratio Total cholesterol to HDL e.g. 4.5:1 Lower is better Periodontal (gum) disease & CVD Chronic inflammation = increased risk of CVD Anti-inflammatory drugs (aspirin) Lowers risk of heart attack Smoking Less smoking = lower cardiovascular death Diet Fruits, vegetables & fish reduce heart attack (CVD) risk Social support Single, divorced, or widowed men = most at risk of CVD Marriage & social support help Anger Anger increased risk of heart attack (CVD) Hostility Cynical hostility = especially harmful to CV health Optimistic bias “It won’t happen to me.” Hypertension = High Blood Pressure Reducing it is difficult because No visible symptoms To reduce it: Lose weight Reduce salt Better diet Fruits, vegetable, whole grain, low-fat dairy Regular physical activity Effect of nonfatal heart attack on sex Fear of having sex Not justified