Important Differences in the Layers of the Alimentary Tract Area of GI Tract Esophagus Stomach Small Intestine Mucosa Stratified columnar epithelium Rugae folds, gastric pits between folds, gastric glands/parietal cells below colum. epith. make HCl: chief cells make zymogen enzymes; lamina propria at base of mucosa (superficial to submucosa); goblet cells make mucus Villi, microvilli on columnar epithelium; brush border enzymes made by columnar cells; goblet cells make mucus here; deep crypts between villi; bounded on deep surface by lamina propria; Duodenum Heavy villi folds, found in retroperitoneal position Illeum Less elaborate villi Large intestine Great numbers of goblet cells, no villi but still has crypts; lamina propria at base Submucosa Muscularis mucosa most superficially, going deep to connective tissue Muscularis Some skeletal muscle with smooth muscle 3 smooth muscle layers: oblique (for mixing), circular, longitudinal for squeezing Serosa Serosa is called aventitia in thoracic cavity Serosa also called visceral periotoneum 2 smooth muscle layers: longitudinal and circular layers; no oblique layer. Serosa also called visceral periotoneum 2 major layers; longitud. layer reduced to 3 sublayers called tenae coli; circular layer also;reduced longit. muscle creating puffy haustra Serosa also called visceral periotoneum; fatty eplipoic appendages hang from visceral peritoneum Duodenal/Brunner's glands evident Peyer's patches in submucosa, increasing in number distally