Review Questions - Lecture 11: DNA Replication
1. Make a drawing of a DNA strand. Include the phosphate, sugar, and show all 4 bases. Note what
types of bonds occur at what locations. Specify which ends are 5’ or 3’.
2. What is the difference between a pyrimidine and a purine?
3. List the differences between DNA and RNA.
4. Make a drawing of what occurs at the origin of replication to separate DNA and initiate synthesis.
Be sure to include all the enzymes and label their function.
5. What is a nucleotide triphosphate?
6. Make a drawing that shows the replication of a leading strand of DNA. Make sure to include all of
the enzymes involved.
7. Make a drawing that shows the replication of a lagging strand of DNA. Make sure to include all of
the enzymes involved.
8. What is an Okazaki fragment?
9. what are two ways that corrections can occur during DNA synthesis?
10. What is a thymine dimer and how does it get repaired?
11. Why do the ends of linear chromosomes continue to shorten with DNA replication?
12. Does chromosome shortening affect the function of the chromosome? Why or why not?
13. What is the role of telomerase in meiosis?