Entropic Forces in Single-Biomolecule Mechanics Philip Nelson, University of Pennsylvania, DMR-25780 Broader impact, education, manpower This year, Nelson added a middle-school component to the research supported by the grant, doing hands-on science instruction for seventh- and eighth-grade students at The Philadelphia School. Far too much school science instruction is based on learning and repeating poorly understood facts. We prefer to show students some intrinsically bizarre phenomenon, let them play with it, saying as little theory as possible, and ask for their ideas. Then we did some quantitative analysis. Finally, we connected to other ideas—for example, the prospects for hydrogen-powered cars. We broke into groups of 3 and performed electrolysis of water. First we got the emotional payoff of exploding the hydrogen! Then we showed that chemically different gases evolved at the anode and cathode, in 2:1 ratio, and also made a master graph across all groups of the volume of gas evolved versus the total electric charge passed through the system, obtaining a surprisingly accurate value for the charge on the electron.