1595 - Developed the first compound microscope Allowed for greater magnification 1665 – Looked at cork under a microscope. First to use the term “cells” Looked like tiny cells/rooms in a monastery. 1674 – Discovered tiny organisms living in water. “animalcules” Tiny organisms exist that we can’t see. Even in the water we drink. 1838 – Determined plants are made of cells. 1839 – Determined animals are made of cells. 1855 – All cells come from other existing cells All living things are made of cells. Cells are the basic units of structure and function in living things. New cells come from other cells. The Weird History of Cell Theory Prokaryote Eukaryote 1) Means “before nucleus” 2) All single celled organisms 3) DO NOT have a nucleus to contain their DNA 4) Very few internal structures 5) All bacteria are prokaryotes 1) Means “true nucleus” 2) Have a nucleus 3) Complex structure – many internal structures (organelles) 4) Can be a single cell or multicellular organisms 5) All animals and plants are Eukaryotes 1) They have a Cell Membrane 2) Contain DNA 3) They show all characteristics of life All Cells Prokaryotes Bacteria Eukaryotes Plant Animal During the 14th century, 25 % or ¼ of Europe was killed by a bacteria (25 million people) Yersinia pestis or Pasteurella pestis Bubonic Plague, also called Black Death This bacterium was spread through fleas and rodents Bubonic Plague - Black Death Cells fall into two broad categories, depending whether they contain a nucleus Nucleus (plural: Nuclei) A large membrane-enclosed structure that contains the cell’s genetic material in the form of DNA Controls many of the cell’s activities Eukaryotic Cells Prokaryotic Cells