AAKAASH VARMA, ROCCO CAPITINI, MICHAEL SCIORTINO, CHRISTINA GOTSIS The following PowerPoint Presentation consists of a concise overview of Chapter 49 in Campbell & Reece’s 7th Edition A.P. Biology Textbook, as well as a series of activities to correspond with each of the following systems covered: sensory, skeletal, and muscular. This PowerPoint Presentation is best viewed as a Slide Show. At the end there is a also a list of online resources to accompany your academic endeavors into this field of biology. Good Luck!!! TRANSDUCE STIMULUS ENERGY AND TRANSMIT SIGNALS TO THE CENTRAL NERVOUS SYSTEM Sensations – action potentials that reach brain via sensory neurons • PERCEPTIONS – resulting interpretations by brain Sensory reception involves stimulus detection by sensory receptors • EXTERORECEPTORS – detect external stimuli • INTERORECEPTORS – detect internal stimuli MECHANORECEPTORS • Sense physical deformation • Bending of plasma membrane increases permeability to sodium and potassium CHEMORECEPTORS • Transmit information about total solute concentration of solution or individual molecules • Involved in gustation (taste) and olfaction (smell) ELECTROMAGNETIC • Detect electromagnetic energy (e.g. visible light, electricity, and magnetism) THERMORECEPTORS • Respond to heat/cold • Enable adaptation to regulate body temperature NOCICEPTORS (A.K.A PAIN RECEPTORS) • Naked dendrites in epidermis • Enable detection of danger TRANSDUCTION AMPLIFICATION TRANSMISSION INTEGRATION • Stimulus energy converted into change in membrane potential (receptor potential) • Result from opening/closing of ion channels in membrane of receptor • Stimulus energy strengthened by cells in sensory pathway • May take place in sensory receptors or in accessory structures • Receptors release excitatory neurotransmitter, causing sensory neuron to transmit action potentials to CNS • Some may contain an axon, extending into CNS, others release neurotransmitters at synapses. • Begins when information is received • May include a decrease in responsiveness during continued simulation (sensory adaptation) • Involves selectivity of receptors in information transmitted to CNS Light enters thru pupil, regulated by size-changing iris Reaches retina where it is captured by specific photoreceptors, rods and cones, which distinguish b/w shapes and colors, respectively Upon activation by light, rod cells become polarized, and thus (de)activate neuronal, bipolar cells that transmit light signals through optic nerve to brain Tympanic membrane vibrates at same frequency as sound waves traveling thru auditory canal Causes small bones to transmit vibrations to the oval window, which creates pressure waves in cochlea fluid, which transmit waves to round window Hair cells of basilar membrane brush against tectorial membrane, creating changes in polarization Lead to increased/decreased neurotransmitter release to auditory nerve Chemoreceptors in taste buds of tongue, bind to specific molecules Once bound, ions diffuse through channels in plasma membrane until they reach sensory neurons, initiating a signal transduction pathway Ions are then transferred to sensory neurons as neurotransmitters Olfactory receptor cells use odorant receptors of chemoreceptors to bind to odorant molecules as they pass thru nasal cavity These trigger signal transduction pathways that, when reaching brain’s olfactory bulbs, create action potentials that allow brain to identify/distinguish odor THE AURORA BOREALIS? A PHOTORECEPTOR, A TYPE OF ELECTROMAGNETIC RECEPTOR! MUSIC? A MECHANORECEPTOR! PERFUME? AN ODORANT RECEPTOR, A TYPE OF CHEMORECEPTOR! PAIN? A NOCICEPTOR (A.K.A PAIN RECEPTOR)! PIZZA? A CHEMORECEPTOR! HEAT? A THERMORECEPTOR! FUNCTION IN SUPPORT, PROTECTION, AND MOVEMENT HYDROSTATIC EXOSKELETON ENDOSKELETON • Fluid held under pressure in closed body compartment • Muscles to change shape of fluidfilled compartments to allow for locomotion and form • Cushions organs from shock • Well suited for aquatic environments but supports crawling/burrowing on land • Main type of skeleton in most cnidarians, flatworms, nematodes, and annelids • Hard encasement deposited on surface • Molluscs: hinged calcareous (calcium carbonate) shells • Arthropods: cuticles composed of chitin in a protein matrix and hardened by calcium salts • Molting occurs w/ each growth spurt • Hard supporting elements buried w/in soft tissues • Sponges: hard spicules of inorganic material or softer protein fibers • Echinoderms: hard plates (ossicles) • Chordates: cartilage/bone • Axial skeleton: skull, vertebral column, and rib cage • Appendicular skeleton: limb bones and appendage-anchoring pectoral/pelvic girdles • Joints provide flexibility for body movements AN ENDOSKELETON (HUMAN)! •Can survive in most different types of environments if nourished well •Has many supporting elements to provide physical support on land •Has a great range of flexibility A HYDROSTATIC SKELETON (EARTHWORM)! •Lives in moist soil •Moves by a process known as peristalsis •It is not raised off ground and is known to crawl and burrow AN EXOSKELETON (LOBSTERS)! •Lives near abrasive shore •Requires shielding from dangerous materials, desiccation, and predators •Must molt periodically A HYDROSTATIC SKELETON (FLATWORMS)! •Locomotion occurs by muscular alteration of body cavities •Subject to shock frequently •Stays close to ground AN ENDOSKELETON (MAMMALS)! •Extremely flexible •Has many soft tissues •Requires a great deal of movement AN EXOSKELETON (INSECTS)! •Very fragile and require protection •Present in many habitats •Growth requires many moltings OCCUR IN ANTAGONISTIC PAIRS AND MOVE SKELETAL PARTS BY CONTRACTING MUSCLE FIBER-BUNDLES – each consist of a single, multi-nuclear cell MYOFIBRILS – thin actin and thick myosin myofilaments that are bundled to form each muscle fiber SARCOMERES – contractile units of muscle that repeat in unit-like frequencies in each myofibril I BAND, A BAND, and H ZONE – contain myofilaments Z LINES – single actin filaments that form its boundaries Thin (actin) filaments slide across thick (myosin) filaments Reduces width of I bands and H zone Shortens sarcomere Shortening of all sarcomeres in a myofibril shortens entire myofibril Graded contractions of whole muscles can be caused by: Varying number of muscle fibers that contract Varying rate at which muscle fibers are stimulated Each branched muscle fiber is innervated by 1 motor neuron that may synapse w/ multiple muscle fibers 1 action potential in a motor neuron produces a twitch MOTOR UNIT – 1 motor neuron and its controlled muscle fibers More rapidly delivered action potentials produce a graded contraction by summation RECRUITMENT – activation of additional motor neurons increases force (tension) TETANUS – fusion of twitches into a sustained contraction Brownish-red pigment that binds oxygen CARDIAC MUSCLE SMOOTH MUSCLE • Found only in heart • Striated cells that are electrically connected by intercalated discs • Can generate action potentials w/o input from nervous system • Found in walls of hollow organs • Lack striations b/c their actin/myosin filaments are not regularly arrayed along cell length • Contract slowly, but to a greater range than striated muscles • Contractions can be initiated by electrically coupled muscles themselves or stimulated by neurons of autonomic nervous system MYOFIBRIL! •Arranged longitudinally bundles of this comprise a muscle fiber •Made of myofilaments CALCIUM (Ca2+) IONS! •Bind to troponin complex to expose myosin-binding sites on thin filament, allowing for contraction SARCOMERE! •Repeating unit of a pattern of light/dark bands, arranged by myofilaments THIN FILAMENT! •Filament w/ two strands of actin, and a strand of regulatory protein MOTOR UNIT! •Collective term for a motor neuron and its controlled muscle fibers TETANUS! •Sustained contraction brought about by fusion of twitches that occur in quick succession SARCOPLASMIC RETICULUM! •Its membrane pumps calcium (Ca2+) ions from the cytosol into its interior to store them and releases them when an action potential is produced TROPOMYOSIN! •Regulatory protein that blocks myosinbinding sites, keeping fiber at rest MUSCLE FIBER! •1 cell w/ multiple nuclei, running muscle length TRANSVERSE (T) TUBULES! •Infoldings of plasma membrane along which action potentials move to spread deep into a fiber SENSORY SYSTEM: •http://frank.mtsu.edu/~jshardo/bly2010/nervous/receptor.html •http://www.spc.cc.tx.us/biology/mhartgraves/Bio2401/Lecture%20Notes/Sensory.pdf •http://www.biology-online.org/9/8_sensory_systems.htm •http://www.slideshare.net/NeurologyGuru/sensory-system SKELETAL SYSTEM: •http://www.mnsu.edu/emuseum/biology/humananatomy/skeletal/skeletalsystem.html •http://www.innerbody.com/image/skelfov.html •http://lyndarandy.tripod.com/skeletalsystem/id1.html MUSCULAR SYSTEM: •http://www.youtube.com/watch?v=EdHzKYDxrKc •http://www.human-body-facts.com/muscular-system.html •http://www.youtube.com/watch?v=gJ309LfHQ3M&feature=related •http://www.besthealth.com/besthealth/bodyguide/reftext/html/musc_sys_fin.html •http://www.ivy-rose.co.uk/HumanBody/Muscles/Muscle_Sliding-Filament.php