Appendix 1. Survey results A. Demographics Participants Men Value 242 92% (222) Years in practice 0-5 6-10 11-20 21-30 34% (83) 22% (53) 30% (73) 14% (33) Geographic location North America Europe Other 52% (126) 37% (90) 11% (26) Specialization General orthopaedics Orthopaedic traumatology Shoulder and elbow Hand and wrist Other 4.6% (11) 37% (89) 16% (39) 36% (86) 7% (17) What is your primary practice/institution setting? Academic Multispecialty group Large private practice, 10 or more providers Small private practice, less than 10 providers Hospital-employed practice 51% (123) 13% (31) 12% (30) 5.4% (13) 19% (45) Supervise trainees 88% (214) How do you perceive the risk of litigation in your practice environment? Very low Low Neutral High Very high 14% (35) 39% (95) 23% (56) 19% (47) 3.7% (9) How many hours a month do you spend on keeping up with published research (journal clubs, reading journal articles, visiting meetings, etc)? 13±10 Political orientation Very liberal Moderately liberal Libertarian Moderately conservative Very conservative 27% (66) 33% (80) 8.3% (20) 17% (40) 15% (36) Do you believe in God, any other deity/deities? Yes, God is a major force in my life Yes, but I don’t practice religion often (eg, go to church) No opinion No, but I consider myself an agnostic (I don’t know if these exist) rather than an atheist 27% (66) 33% (80) 8.3% (20) 17% (40) No, I am an atheist 15% (36) Would you consider yourself a religious person? Yes, and I worship regularly Yes, but I do not worship regularly Moderately, or I don’t really think about it No, not really, but I don’t rule it out Not at all, I am an atheist (I believe there is no God) 20% (49) 25% (61) 13% (32) 26% (62) 16% (38) B. Uncertainty How much uncertainty is there in your daily medical decisions? The majority of what I do is understood and established in the literature; there is little uncertainty in daily medical decisions I encounter in my practice I occasionally come across something that I recognize as being uncertain in my practice I frequently regard medical decisions as being uncertain I almost always see uncertainties in my daily medical decisions In my practice, the medical decisions I make are always uncertain to various degrees, and there is almost always no absolute truth to the matter at hand What percentage of your patient contacts is associated with substantial uncertainty in diagnosis or treatment options? Less than 10% 10%-30% 30%-50% 50%-70% 70%-90% More than 90% How confident are you in the correctness of your daily routine diagnostic or therapeutic decisions? My decisions are based on the established literature and are therefore always correct I am nearly always sure of the decisions I make Approximately 25% of the time I feel an element of insecurity about the decision I am making I am unsure of about half of the decisions I make I am unsure of more than half of the decisions I make When I make a decision about an uncertain topic that has no published evidence supporting it, I feel: This does not happen, because just about everything is well worked out and the decisions I make are supported by evidence Confident that I am making the right choice, although I recognize that there is no "right answer”; I don't really think that I am wrong, but rather that the optimal answer may not exist Neither confident nor unconfident; the decision is made based on the standard of care established by my specialty Not at all confident; I feel uneasy about making these types of decisions because I think that I might be wrong Very uneasy; decisions like this make me very uncomfortable and I try to avoid them; I am probably wrong C. Trust in the orthopaedic literature Has the acquisition of more and more knowledge in your field made you more confident in your decisions? 13% (31) 36% (88) 35% (84) 9.5% (23) 6.6% (16) 40% (96) 40% (95) 16% (38) 5.0% (12) 0.41% (1) 0% (0) 3.7% (9) 51% (124) 41% (100) 3.7% (9) 0% (0) 1.2% (3) 62% (149) 30% (72) 6.6% (16) 0.83% (2) No, more and more experience and "knowledge" has only made me see that nothing is really certain at all No, I have gained more knowledge but with more knowledge has come more recognition of what we don't know I am not sure Yes, I am more confident but my decisions are still at times uncertain; I recognize the limitations of what we know Yes, with more experience and knowledge I am much more confident now and I make better decisions It is permissible and justified to chose to do a surgery based on my personal estimation that it will help the patient, even if the evidence does not support it? Agree strongly Agree, but not strongly Sometimes agree, depending on the type of intervention Disagree, but not strongly Disagree strongly Do you think that evidence-based medicine guidelines should limit physicians’ autonomy in making surgical decisions? No, I do not think that my autonomy should ever be constrained; the evidence applies only to populations, not to individuals, and we physicians should be free to decide on treatment plans even if it goes against established evidence No, but when we make a decision that goes against established evidence or guidelines, we should be expected to provide reasons why before the treatment is accepted or covered by insurance No, but when we make decisions that go against established guidelines, we are in a very gray area and we have an ethical obligation to tell our patients and insurance providers that we are not sure Not sure Yes, but there should be times when we can petition the governing body/insurance carrier to allow nonevidence-based treatments Yes, we should not prescribe treatments that are not evidence-based and that do not have published evidence supporting them 4.7% (11) 35% (82) 3.4% (8) 46% (108) 11% (25) 13% (30) 27% (64) 50% (116) 5.1% (12) 5.1% (12) 14% (33) 43% (101) 22% (51) 7.7% (18) 11% (25) 2.6% (6) How often do orthopaedic research studies draw incorrect conclusions? Most published research articles are false or misleading Approximately half of published articles have incorrect or misleading conclusions A minority of published articles have incorrect or misleading conclusions It’s rare that published articles have misleading or incorrect conclusions 0.85% (2) 44% (102) 55% (129) 0.43% (1) D. Confidence bias Rate your diagnostic skills compared with other practitioners in your field. Top 5% Top 25% Above average Average Below average Bottom 25% Bottom 5% 20% (47) 37% (87) 26% (60) 17% (40) 0% (0) 0% (0) 0% (0) Rate your surgical skills compared with others in your field. Top 5% 25% (58) Top 25% Above average Average Below average Bottom 25% Bottom 5% If a paper from a leading institution says that 80% of their patients had good or excellent outcomes, the chance that in your patients will have a similar outcome is: Far better; my patients almost always exceed published outcome Slightly better than the published results The same; no reason to think my results would be any different Worse by a little; the expected outcome in the literature is idealized and likely biased and it is likely that my patients will not exceed published outcome reports Much worse; I am likely to be not as skilled as the authors, given their prominence and reputation 29% (69) 30% (70) 15% (34) 0.85% (2) 0.43% (1) 0% (0) 2.1% (5) 9.4% (22) 57% (133) 30% (71) 1.3% (3) E. Statistical understanding A patient has a painful shoulder; imaging studies do not show a rotator cuff tear; however, tendinosis is noted; the patient is not satisfied after physical therapy for several months and has had no relief with three cortisone injections; an arthroscopic decompression and bursectomy are done and the bursa was noted to be hypertrophic at the time of surgery; the patient’s pain resolves completely and he has no more symptoms and complete return to function; does this prove that the hypertrophic bursa was the cause of the pain and that the surgery cured the condition? Yes, this is proof beyond doubt; the tendinosis was the cause of the pain and the surgery cured it Yes, to the degree that things like this offer proof, this does “prove” it; the pain could have resolved on its own, but the surgery likely got rid of the painful bursa and therefore “cured” the patient I can't say Not in a strict sense; proof of causation is not established here but it is very probable that the cause of the pain was the hypertrophic bursa and the surgery got rid of the pain generator, curing the symptoms No, this is a logical fallacy; the pain relief and surgery are associated but there is a causal relationship has not been demonstrated (correct) 1.7% (4) 16% (37) 12% (27) 47% (110) 24% (56) In interpreting a paper on outcome of a surgical intervention that shows 80% good and excellent outcomes, when applied to a particular patient, 80% good/excellent means: That there is an 80% chance that in this patient the result will be good or excellent That of 100 patients, 80 would be expected to have good or excellent outcome (correct) That this patient can expected to be 80% healed after treatment 12% (27) 87% (204) 1.3% (3) An MRI you are going to order for a patient has a (hypothetical) sensitivity of 90% and a specificity of 90%; if there is a 10% chance the patient has the condition, then: A positive result means that there is a 90% chance of the condition being present The test increased the probability of a positive result to only 50% (correct) A positive result increases the probability to less than 20% 58% (135) 11% (26) 6.0% (14) We cannot calculate this because only a subjective probability is given and not a base rate A (hypothetical) newly developed MRI technique has a sensitivity and specificity of 95% to detect a specific cartilage lesion; approximately one in a thousand people have this lesion; which of the following statements is true? A positive result on this test means that there is a 95% chance that the result is true (a true-positive) A positive result on this test means that the chance the patient has the condition is approximately 50% A positive result on this test means that the chance the patient has the condition is approximately 2% (correct) A negative result on this test means that the disease is ruled out to 95% probability There are 4 cards as shown, and each card has number on one side and a letter on the other: which cards do you have to turn over to validate or invalidate the rule “if there is a vowel on one side, the other side has an even number”? Just the A card The A and the 4 cards The A and the 7 cards (correct) The D and the 4 cards p value < 0.05 means: The chances are less than 1 in 20 that a difference would be found again if the study were repeated The same as a p value of < 0.01 The probability is less than 1 in 20 that a difference this large could occur by chance alone (correct) The chance is better than 95% that the study is correct F. Other questions You are confronted with an uncertain situation, perhaps a decision to operate or treat nonoperatively, where both choices seem reasonable and the decision is difficult; your response to a patient asking you a question about how the outcome would be different between the two is (pick your most typical response): I don’t know which treatment is best I’m not entirely sure, and I am going to try to look this up We, in the medical community, don't know the answer to that; some things are just not known I make a guess based on what is most probable, because patients do not respond well to uncertainty, and my role is to not only treat to the best of my ability, but to provide reassurance This does not happen often enough to me in my field of specialty practice for me to have a typical response; most of what I do is quite certain and well studied When it comes to decisions that are uncertain and without an established consensus, I make a decision based on (pick the best): My past experience What the least invasive choice is What the patient wants What I think the medical community would most accept What I am feeling at the time 25% (59) 57% (127) 4.0% (9) 13% (28) 26% (59) 20% (44) 61% (137) 13% (30) 5.4% (12) 7.2% (16) 2.7% (6) 80% (178) 10% (23) 22% (49) 13% (30) 40% (90) 19% (43) 4.9% (11) 54% (121) 13% (30) 23% (51) 7.2% (16) 2.2% (5) How has your confidence changed since you graduated training? Decreased Unchanged Increased 7.6% (17) 7.2% (16) 85% (190)