DNA • DNA stands for deoxyribonucleic acid. • Genes are found on chromosomes. • Chromosomes are made up of proteins and DNA. • Gene material (DNA) must supply instructions for building cell organelles and cell processes. • Gene material (DNA) must copy each time cell divides. Nucleotides • Nucleotides- sub units of DNA, made up of sugar, phosphate and a base • 4 bases are adenine, thymine, guanine, and cytosine. Each have a different shape. • Chargaff’s Rules – A = T, C = G • Rosalind Franklin suggested DNA is a spiral shape. • Watson and Crick concluded that DNA is a twisted ladder shape = double helix. The double helix • Sides of the ladder are made up of alternating sugar and phosphate molecules. • Rungs (steps) of the ladder are the pair of bases. • One side of DNA can copy itself easily, it splits down the middle and each side is used as a template for the new side. Function of DNA • DNA directs every cell in your body how and when to synthesize proteins for its activities and development. • Proteins determine different shapes, sizes, colors, etc. • During cell division, the DNA unzips and gives each new cell a copy of itself. Uses of DNA • Identifying criminals. • Proving innocence • Determining heredity (family relationships) • Treating illnesses • Raising better crops • Creating new medicines • Better livestock Vocabulary • Incomplete dominance – when one trait is not completely dominant over the other, they both appear in the phenotype. • Mutations- a change in the order of the bases in an organisms DNA. • Mutagen – a physical or chemical agent that can cause a mutation to occur in DNA. • Pedigree – a diagram used by genetic counselors to predict if hereditary material will be passed to future generations.