Version 2 Universidade Nacional da Irlanda em Galway -- Ciência sem Fronteiras PhD Project Template Use one form per project Please complete & submit to international@nuigalway.ie as soon as possible, and by 27/11/2012 In your email, begin the subject line with [SWB] (be sure to use square brackets) to ensure that your email is filed correctly. Emails will be automatically filed PI name & contact details: Dr Aoife Boyd and Prof Afshin Samali Aoife.Boyd@nuigalway.ie; Afshin.Samali@nuigalway.ie School: Natural Sciences Has project been agreed with head (or nominee) of proposed registration school? Yes Research Centre / group affiliation: Microbiology , National Centre for Biomedical Engineering Science www.nuigalway.ie/microbiology http://ncbes.nuigalway.ie Research group / centre website: PI website / link to CV: www.nuigalway.ie/microbiology/ab.html http://ncbes.eurhost.net/bio/afshin-samali.aspx Brief summary of PI research / research group / centre activity (2 or 3 lines max): Dr Boyd leads the Pathogenic Mechanisms group which characterises the molecular virulence mechanisms of pathogenic bacteria. Prof Samali leads the Cell Stress group in the Apoptosis Research Centre (ARC). Title & brief description of PhD project (suitable for publication on web): Title: Host cell responses to pathogenic bacteria – the role of the cellular stress pathways. Description: The cellular responses to stress can range from adaptive responses to cell death. It has recently been shown that pathogenic bacteria can manipulate human cell activities by controlling cellular stress responses. It is now important to understand the mechanisms by which the bacteria manipulate the host cells’ stress response pathways, and the consequences for the bacteria and for the cell. The PhD researcher will investigate this topic and thereby advance knowledge of both bacterial virulence and cellular stress. Version 2 Universidade Nacional da Irlanda em Galway -- Ciência sem Fronteiras Unique selling points of PhD project in NUI Galway: NUI, Galway provides the unique integration of the host-pathogen expertise of Dr Boyd with the cell stress expertise of Prof Samali. This will provide the PhD researcher with a stimulating research project, during which they will acquire excellent skills and experience for their future career. The candidate will interact closely with both Apoptosis Research Centre and with Infectious Disease research cluster. Name & contact details for project queries, if different from PI named above: Please indicate the graduates of which disciplines that should apply: Biology, Microbiology, Cell Biology, Biochemistry, Molecular Biology Ciência sem Fronteiras / Science Without Borders Priority Area: Please indicate the specific programme priority area under which the proposed PhD project fits- choose only one (tick box): Engineering and other technological areas Pure and Natural Sciences (e.g. mathematics, physics, chemistry)/Physical Sciences (Mathematics, Physics, Chemistry, Biology and Geosciences) Health and Biomedical Sciences / Clinical, Pré-clinical and Health Sciences √ Information and Communication Technologies (ICTs), Computing Aerospace Pharmaceuticals Sustainable Agricultural Production Oil, Gas and Coal Renewable Energy Minerals, Minerals Technology Biotechnology Nanotechnology and New Materials Technologies for Prevention and Mitigation of Natural Disasters Bioprospecting and Biodiversity Marine Sciences Creative Industry New technologies in constructive engineering Please indicate which of the following applies to this project (referring to Science Without Borders arrangements): Suitable only as a Full PhD (Y/N): _ ____ Available to candidates seeking a Sandwich PhD arrangement (Y/N): _____ Suitable for either/Don’t know: __Y___