List of Abbreviations AAD AD AEDS APC APT AUC BA bid BSA cAMP CD CDLQI CGRP CI CLA Cmax Cmin CsA CSF CYP3A4 DC DC2 DFI DLQI DQLS DSQL DTH EAD EASI EAU ED50 ELISA FcεRI American Academy of Dermatology atopic dermatitis atopic eczema/dermatitis syndrome antigen-presenting cell atopy patch test area under the curve bioavailability twice daily body surface area cyclic adenosine monophosphate cluster designation Children’s Dermatology Life Quality Index calcitonin gene-related peptide confidence interval cutaneous lymphocyte-associated antigen peak concentration trough concentration cyclosporin A colony-stimulating factor cytochrome P450, subfamily IIIA, polypeptide 4 dendritic cell type 2 dendritic cell Dermatitis Family Impact Dermatology Life Quality Index Dermatology Quality of Life Scales Dermatology Specific Quality of Life delayed-type hypersensitivity extrinsic atopic dermatitis Eczema Area and Severity Index experimental autoimmune uveitis median effective dose enzyme-linked immunosorbent assay high-affinity IgE receptor XV List of Abbreviations FcεRII FcR FDA FK 506 FKBP FLQA-a FLQA-d GHQ GM-CSF GRE GVHD HLA HLA-DR HPLC-(MS/MS) IAD IC50 ICAM ICH IDDM IDEC IDQOL IFN Ig IGF IL ISAAC LC LLNA LP MBSA mEASI MHC MLR MTX NF-κB NF-AT NGF NK cell NMR NO NSAID PASI low-affinity IgE receptor fragment crystallisable receptor Food and Drug Administration tacrolimus FK 506-binding protein Freiburg Life Quality Assessment (for allergies) Freiburg Life Quality Assessment (for dermatoses) General Health Questionnaire granulocyte-macrophage colony-stimulating factor glucocorticoid response element graft-versus-host disease human leukocyte antigen D-related human leukocyte antigen high pressure liquid chromatography (tandem mass spectroscopy) intrinsic atopic dermatitis inhibitory concentration 50 intercellular adhesion molecule International Conference on Harmonisation insulin-dependent diabetes mellitus inflammatory dendritic epidermal cell Infants’ Dermatitis Quality of Life Index interferon immunoglobulin insulin-like growth factor interleukin International Study of Asthma and Allergies in Childhood Langerhans cell local lymph node assay lichen planus methylated bovine serum albumin modified Eczema Area and Severity Index major histocompatibility complex mixed lymphocyte reaction methotrexate nuclear factor kappa B nuclear factor of activated T cells nerve growth factor natural killer cell nuclear magnetic resonance nitric oxide non-steroidal anti-inflammatory drug Psoriasis Activity and Severity Index XVI List of Abbreviations PBMC PDE PDI PFC pFv PG PGE PGI PICP PIIINP PINP PPD PPIase PPV PSI PUVA QALY QoL RA RA RANTES RAST RF SCC SCORAD SD SDZ ASM 981 SEA SEB SEM SF-36 SIS t½ TCR Th TIM tmax TNF UKSIP UVA UVB VCAM peripheral blood mononuclear cell phosphodiesterase Psoriasis Disability Index plaque-forming cell protein Fv prostaglandin prostaglandin E Patient Generated Index carboxy-terminal propeptide of procollagen I amino-terminal propeptide of procollagen III amino-terminal propeptide of procollagen I paraphenylenediamine peptidyl-prolyl cis-trans isomerase positive predictive value Psoriasis Severity Index psoralen plus UVA Quality Adjusted Life Year quality of life respiratory allergies (Chap. 1) rheumatoid arthritis (Chap. 11) regulated upon activation, normal T-cell expressed and secreted radioallergosorbent test rheumatoid factor squamous cell carcinoma Severity Scoring of Atopic Dermatitis standard deviation pimecrolimus Staphylococcus aureus enterotoxin A Staphylococcus aureus enterotoxin B standard error of the mean Short Health Form Survey 36 skin immune system half-life of elimination T-cell receptor T-helper cells topical immunomodulator time to peak concentration tumour necrosis factor United Kingdom Sickness Impact Profile long-wave ultraviolet radiation short-wave ultraviolet radiation vascular cell adhesion molecule XVII