6/11/2012 Levels of Organization • • • • • Chemical Cellular Tissue Organs System Level • Organismic Chapter 19 Homeostasis & Organization of the animal body 1-2 4 Primary Tissues 1. 2. Epithelial Tissue: – covers surfaces – lines hollow organs, cavities and ducts – forms glands (beneath surface) 1. Exocrine glands 2. Endocrine Glands Connective Tissue: Living cells surrounded by a non-living matrix – can be liquid, gel-like, hard – supports - binds structures together – stores energy as fat – provides immunity to disease – transports things – Includes: bone, cartilage, blood, tendons, ligaments, fat 4 Primary Tissues 3. Muscle Tissue: – cells shorten in length producing movement – produce kinetic energy 3 types: 1. Skeletal: long, striated, muli-nuclei, voluntary 2. Cardiac: single nuclei, striated, branched, involuntary 3. Smooth muscle: no striations, tapered ends, involuntary, single nuclei 4. Nerve Tissue: – cells that conduct electrical signals – detect stimuli inside and outside the body – Communication 2 types of nervous tissue cells: glial cells & neurons - Neuron anatomy! 3-3 3-4 Organ Systems: Two or more organs working together to do a job Integumentary system Skin is an organ that contains all 4 tissue types 3-5 Skeletal system Muscular system Lymphatic system A-6 1 6/11/2012 Organ Systems Organ Systems Circulatory system Nervous system Urinary system Respiratory system A-7 Digestive system Male reproductive system Female reproductive system Endocrine system Figure A.11 Figure A.11 A-8 Negative Feedback Control of Blood Pressure Homeostasis • Homeostasis – the body’s ability to detect change, activate mechanisms that oppose it, and thereby maintain relatively stable internal conditions Person rises from bed Negative Feedback, Set Point Blood pressure rises to normal; homeostasis is restored Blood drains from upper body, creating homeostatic imbalance 75 70 Set point Cardiac center accelerates heartbeat 65 Baroreceptors above heart respond to drop in blood pressure 60 Time Baroreceptors send signals to cardiac center of brainstem 1-9 Positive Feedback 1-10 Circulatory Systems • Amplifes the change • Functions of circulatory system • Transportation of stuff – leads to greater change in the same direction – feedback loop is repeated – change produces more change – Oxygen from lungs or gills to the tissues – Carbon dioxide from tissues to the lungs or gills – Nutrients from the digestive system to the tissues – Hormones – Waste products and toxic substances to the liver and the kidney for excretion • Regulate body temperature • Protect from viruses & bacteria 1-11 2 6/11/2012 Circulatory Systems • Open circulatory system • Circulatory systems have three main components: – Blood – Blood vessels – Heart heart blood bathes internal organs • Animals have two types of circulatory systems: – Open circulatory system – Closed circulatory system blood vessels opening with valves tubular hearts hemocoel (a) Open circulatory system • Fish heart • Closed circulatory system Fig. 20-1a gill capillaries heart extracellular fluid ventricle vessels branch in each organ atrium vessel hearts small vessels (b) Closed circulatory system Fig. 20-1b • Amphibian, and most reptiles’ heart body capillaries (a) Fish Fig. 20-2a • Mammals and birds’ heart lung capillaries lung capillaries atria atria ventricle ventricle body capillaries (b) Amphibians, most reptiles Fig. 20-2b body capillaries (c) Mammals, birds Fig. 20-2c 3 6/11/2012 • The human heart and its valves and vessels • The cardiac cycle pulmonary artery (to left lung) aorta superior vena cava Oxygenated blood is pumped to the body Deoxygenated blood is pumped to the lungs left atrium pulmonary artery (to right lung) pulmonary veins (from left lung) pulmonary veins (from right lung) atrioventricular valve semilunar valves Deoxygenated blood from the body enters the right ventricle right atrium left ventricle thicker muscle of left ventricle atrioventricular valve inferior vena cava Atria contract, forcing blood into the ventricles descending aorta (to lower body) right ventricle Oxygenated blood from the lungs enters the left ventricle Blood fills the atria and begins to flow passively into the ventricles Then the ventricles contract, forcing blood through the arteries to the lungs and the rest of the body The cycle ends as the heart relaxes Fig. 20-3 What Is Blood? • The heart’s pacemaker and its connections The sinoatrial node electrical signal starts the atrial contraction AV node • Blood transports dissolved nutrients, gases, hormones, and wastes through the body. – It has two major components: • Fluid, called plasma • Cellular components—including red blood cells, white blood cells, and platelets—which are suspended in the plasma – The cellular components are produced in bone marrow and later move into the blood. Unexcitable tissue separates the atria and ventricles The signal spreads, causing the atria to contract excitable fibers The atrioventricular node transmits the signal to the ventricles with a slight delay Fig. 20-4 The signal travels to the base of the ventricles Excitable fibers transmit the signals to ventricular cardiac muscle, causing contraction from the base upwards Fig. 20-6 • Blood cells neutrophil • Plasma is primarily water and dissolved substances. neutrophil – Plasma is 90% water. – Dissolved in the plasma are proteins, hormones, nutrients, salts, and wastes, such as urea. monocyte basophil eosinophil red blood cells lymphocyte (a) Erythrocytes (b) White blood cells platelets megakaryocyte (c) Megakaryocyte forming platelets Fig. 20-9 4 6/11/2012 • Red blood cells carry oxygen from the lungs to the tissues. – The most abundant cells in the blood are red blood cells. – Red blood cells get their red color from hemoglobin, an iron-containing protein that can bind up to four oxygen molecules. – Hemoglobin picks up oxygen in the lungs, where oxygen is at high concentration, and releases it in other tissues of the body, where the oxygen concentration is low. • Lymphocytes are responsible for the immune response against disease. • White blood cells (Leukocytes) help defend the body against disease. – Less than 1% of blood cells – Play a key role in the body’s resistance to disease. – There are five types of white blood cells: • Neutrophils • Eosinophils • Basophils • Lymphocytes • Monocytes • Platelets are cell fragments that aid in blood clotting. – Neutrophils and monocytes engulf foreign particles. – Platelets play a key role in blood clotting. – Blood clotting starts when platelets contact an irregular surface, such as a damaged blood vessel, where they partially block the opening. Fig. 20-10 • The platelets and injured tissue initiate a complex sequence of reactions among plasma proteins, which results in a fibrous network, called fibrin, that traps red blood cells and closes the wound. platelets 20.4 What Are The Types And Functions Of Blood Vessels? white blood cell fibrin strands red blood cell Fig. 20-11 5 6/11/2012 • As it leaves the heart, blood travels from 1) arteries to 2) arterioles to 3) capillaries to 4) venules to 5) veins, and finally, it returns to the heart. jugular vein carotid artery aorta pulmonary artery superior vena cava 20.4 What Are The Types And Functions Of Blood Vessels? • Structures and interconnections of blood vessels lung capillaries inferior vena cava capillary network heart arteriole liver intestine kidney smooth muscle precapillary sphincters venule femoral vein femoral artery cross section capillary valve smooth muscle connective tissue artery vein Fig. 20-12 Fig. 20-13 • Red blood cells flow through a capillary. • Capillaries are microscopic vessels through which nutrients and wastes are exchanged. – Diffusion of nutrients and wastes occurs in capillaries – Walls are only one cell thick, substances can cross a capillary cell’s plasma membrane and easily move into or out of capillaries (diffusion). Red blood cells must pass through capillaries in single file Capillary walls are thin and permeable to gases, nutrients, and cellular wastes Fig. 20-14 • Valves direct the flow of blood in veins. valve open valve closed muscle contraction compresses vein relaxed muscle valve closed Fig. 20-15 6