53 Diverticular Disease C.S. Pitchumoni Questions and Answers 1. One of the structural abnormalities of left-sided diverticulosis is: a.Thickening of muscle wall and shortening b.Thinning of muscle wall and lengthening c.Circular muscle contraction in the sigmoid colon d.Herniation of all layers of the wall of colon Age alone is not a determinant for segmental resection or surgical management. 3. Diverticular bleeding is best described by which one of the following? a.A cause of anemia in the elderly. b.Painless and brisk. c.Characterized by slow oozing of altered blood. d.A contraindication for early colonoscopy. Answer: A Answer: B The large majority of colonic diverticula on the left side of the colon are pseudodiverticula, meaning that the divertic has only the mucosal layer, in contrast to right-sided diverticula which are true diverticula with all the layers of the bowel wall. The diverticula herniate through the bowel wall at weak points in the circular muscle where the main blood vessels pass to supply the colonic mucosa. Sustained segmental contraction results in increased intraluminal pressure leading to outpouching of the mucosa. Hypertonicity and colonic muscular hypertrophy probably precede diverticular formation. Intermittent contractions divide the colonic lumen into a series of small compartments (small bladders). Occult bleeding and iron deficiency anemia are not features of diverticular disease. Diverticular bleed is typically sudden in onset, profuse, self-limited, and painless. Colonoscopy after a rapid lavage in patients with suspected diverticular bleed is recommended because of the potential for arresting the bleed. 2.A true statement with regard to diverticulitis includes all of the following except: a.It is a form of segmental colitis b.It is similar to appendicitis c.May cause colovesical fistula d.Needs segmental resection of the sigmoid in the elderly Answer: D Diverticulitis is inflammation of a diverticulum occurring as a result of gross or microscopic perforation with an extra-luminal pericolic infection. The perforation may be walled-off and localized. The pathogenesis is similar to that of appendicitis. Aminosalicylic acid (5-ASA) is a newer modality of therapy based on the concept that “segmental colitis” develops. 4. Diverticular bleeding in the older adults is characterized by which one of the following? a.Often coincides with diverticulitis b.Is often life threatening and is an indication for early surgery c.A second episode may occur in over 25% d.Surgery is contraindicated because of multiple comorbid conditions Answer: C Diverticular bleed seldom coincides with an episode of diverticulitis. Bleeding complicates only 5% of all cases of colonic diverticulosis. A second bleeding episode may occur in 22–38%, and a third recurrence in up to 50% of patients. When surgery is indicated, comorbidity is not a deterrent; the decision should be individualized. 5.A 70-year-old patient is admitted with the history of severe LLQ pain, fever, and leukocytosis. An abdominal CT scan showed evidence of diverticulitis. A previous colonoscopy 2 years ago following an episode of diverticulitis was negative except for presence of sigmoid C.S. Pitchumoni and T.S. Dharmarajan (eds.), Geriatric Gastroenterology, DOI 10.1007/978-1-4419-1623-5_53, © Springer Science+Business Media, LLC 2012 511 512 diverticula. Patient is otherwise in good health. He was treated with IV antibiotics and IV fluids and made good clinical improvement. A well accepted management option at this time is: a.Endoscopic stent placement. b.Surgical resection of the involved segment. c.Strict dietary precautions avoiding nuts, popcorn, and tomatoes. d.A diet rich in soluble fiber. C.S. Pitchumoni Answer: D Colonic stent placement is an indication only when there is a stricture prior to definitive surgery. First episode of diverticulitis, if uncomplicated, is not an indication for surgery. Although many clinicians advise patients to avoid nuts and seeds in their diet, there is no scientific evidence for their elimination in the diet. Although data is contradictory, a diet rich in soluble fiber may help prevent complications of diverticular disease.