Unit D: Genetic Processes Chapter 6: Complex Patterns of Inheritance - While some genes influence phenotype according to Mendel’s straightforward laws of dominance, many genes influence phenotype in more complex ways. Specific Expectations: D1.1: analyze, on the basis of research, some of the social and ethical implications of research in genetics and genomics. (6.3) D1.2: evaluate, on the basis of research, the importance of some recent contributions to knowledge, techniques, and technologies related to genetic processes. (6.3) D2.1: use appropriate terminology related to genetic processes. (6.1, 6.2) D2.3: use the Punnett square method to solve basic genetic problems involving monohybrid crosses, incomplete dominance, co-dominance, dihybrid crosses, and sex-linked genes. (6.1, 6.2) D3.3: explain the concepts of genotype, phenotype, dominance, co-dominance, recessiveness, and sex linkage according to Mendelian laws of inheritance. (6.1, 6.2) D3.4: describe some genetic disorders caused by chromosomal abnormalities or other genetic mutations in terms of chromosomes affected, physical effects, and treatments. (6.1, 6.2) 6.1: Beyond Mendel’s Observations of Inheritance pg. 242 - 250 Key Terms: Incomplete dominance, co-dominance, heterozygous advantage, contiuous variation, and polygenic trait. Incomplete Dominance Incomplete Dominace and Human Disease Co-dominance Sickle Cell Anemia Learning Check: 1-6 pg. 244 Multiple Alleles Human Blood Groups Rabbit Coat Colour Clover Leaf Patterns Practice Problems: 1 – 10 pg. 247 Environmental Effects on Complex Patterns of Inheritance Polygenic Inheritance 1 – 11 pg. 250 Activity 6.1: Identifying a Polygenic Trait 1–2 pg. 248 Study Guide: Self Assessment 1 – 12 SG. 84 – 85 Incomplete Dominance and Co-dominance (6.1) 1–4 SG. 86 – 87 Polygenic Traits (6.1) 1–4 SG. 88 – 89 Review Questions: 6.2: Inheritance of Linked Genes pg. 251 - 259 Key Terms: linked genes, and sex-linked genes Linked Genes Crossing Over and the Inheritance of Linked Genes Using Gene Linkage for Chromosome Mapping Learning Check: 7 – 12 pg. 253 Sex-linked Inheritance Sex-linked Genes The Red and White Eyes of Fruit Flies Sex-linked Traits in Humans Colour Vision Deficiency: An X-linked Recessive Trait Hemophilia: A Common Sex-linked Trait in Humans Practice Problems: 11 – 20 pg. 258 1 – 15 pg. 259 Barr Bodies: Inactive X Chromosomes Review Questions: Thought Lab 6 – B: Sex-linked Crosses Study Guide: Linked Genes (6.2) Sex-linked Traits (6.2) pg. 270 -271 1–2 SG. 90 1–3 SG. 91 – 92 6.3: The Future of Genetics Research pg. 260 - 267 Key Terms: bioinformatics, genomics, genetic profile The Human Genome Project What’s in Our Genome? The Development of Bioinformatics Learning Check: 13 – 18 pg. 262 Genomics: The Study of Genomes Linking Genetic Variations to Disease Beyond the Genome Sequence Studying Gene Expression Studying Gene Expression Using Microarrays Genetic Information: Public Benefits and Concerns What Can Happen to Information from a Genetic Profile? Ownership of Genetic Information 1 – 15 pg. 267 Activity 6.2: Accessing Genetic Information 1–2 pg. 262 Study Guide: Genetic Research (6.3) 1–3 SG. 93 – 94 Review Questions: Bringing It All Together Practice Test SG. 95 1 – 14 SG. 96 – 97