BIOLOGY II: CHAPTER15 NAME_____________________ Chapter 15: Cardiovascular System I. Introduction A. The heart pumps _______________________________________________________ liters of blood through the body each day. B. The cardiovascular system includes __________________________________________________________________________ C. The pulmonary circuit ___________________________________________________________________________________ D. The systemic circuit ____________________________________________________________________________________ II. Structure of the Heart A. Size and Location of the Heart 1. An average size of an adult heart is generally __________________________________________________________ 2. The heart is bounded laterally by_______________________, anteriorly by, and posteriorly by ___________________ 3. The base of the heart lies beneath ___________________________________________________________________ 4. The apex of the heart is at the level of ________________________________________________________________ B. Coverings of the Heart 1. The pericardium is_______________________________________________________________________________ 2. The fibrous pericardium is_________________________________________________________________________ 3. The visceral pericardium is ________________________________________________________________________ 4. The parietal pericardium is ________________________________________________________________________ 5. The pericardial cavity is __________________________________________________________________________ 6. Serous fluid reduces _____________________________________________________________________________ C. Wall of the Heart 1. The three layers of the heart wall are _________________________________________________________________ 2. The epicardium is composed of _____________________________________________________________________ 3. The middle layer is the ___________________________________________________________________________ 4. The myocardium is composed of____________________________________________________________________ 5. The inner layer is the _____________________________________________________________________________ 6. The endocardium consists of _______________________________________________________________________ 7. The endocardium of the heart is continuous with _______________________________________________________ D. Heart Chambers and Valves 1. The two upper chambers of the heart are ______________________________________________________________ 2. Auricles are ____________________________________________________________________________________ 3. The two lower chambers of the heart are ______________________________________________________________ 4. The interatrial septum separates ____________________________________________________________________ 5. The interventricular septum separates ________________________________________________________________ 6. An atrioventricular orifice is _______________________________________________________________________ 7. An atrioventricular orifice is protected by _____________________________________________________________ 8. The atrioventricular sulcus is located ________________________________________________________________ 9. The right atrium receives blood from ________________________________________________________________ 10. The tricuspid valve is located______________________________and functions to ___________________________ 11. Chordae tendinae are______________________________and function to __________________________________ 12. Papillary muscles are located______________________________and contract when __________________________ 13. The right ventricle receives blood from ______________________________________________________________ 14. The right ventricle pumps blood into________________________________________________________________ 15. The pulmonary trunk divides into __________________________________________________________________ 16. Pulmonary arteries deliver blood to _________________________________________________________________ 17. The pulmonary valve is located______________________________and opens when __________________________ 18. Pulmonary veins carry blood from the______________________________to the______________________________ 15-1 19. Blood passes from the left atrium into the ____________________________________________________________ 20. The mitral valve is located______________________________and functions to _____________________________ 21. The left ventricle pumps blood into _________________________________________________________________ 22. The aortic valve is located ______________________________and opens when _____________________________ 23. The tricuspid and mitral valves are also called______________________________because _____________________ 24. The pulmonary and aortic valves are also called______________________________because ___________________ E. Skeleton of the Heart 1. The skeleton of the heart is composed of______________________________________________________________ 2. The skeleton of the heart provides attachments for ______________________________________________________ F. Path of Blood Through the Heart 1. Blood that is _________ in oxygen and _________________________________________ in carbon dioxide enter the ___________________________________________________ of the heart through venae cavae and the coronary sinus. 2. As the right atrium contracts, blood passes into ________________________________________________________ 3. When the right ventricle contracts, blood moves into the _________________________________________________ 4. From the pulmonary arteries blood enters the __________________________________________________________ 5. The blood loses ____________ in the lungs and picks up _________________________________________________ 6. Freshly oxygenated blood returns to the heart through ___________________________________________________ 7. The pulmonary veins deliver blood to the _____________________________________________________________ 8. When the left atrium contracts, blood passes into _______________________________________________________ 9. When the left ventricle contracts, blood passes into _____________________________________________________ G. Blood Supply to the Heart 1. The first two branches of the aorta are _______________________________________________________________ 2. Coronary arteries supply __________________________________________________________________________ 3. The circumflex artery is located______________________________and supplies _____________________________ 4. The anterior interventricular artery is located______________________________and supplies ___________________ 5. The posterior interventricular artery is located______________________________and supplies __________________ 6. The marginal artery is located______________________________and supplies _______________________________ 7. Blood flow in coronary arteries is poorest during______________________________because ___________________ 8. Cardiac veins drain ______________________________________________________________________________ 9. The coronary sinus is_____________________________________________________________________________ III. Heart Actions A. Introduction 1. Atrial systole is _________________________________________________________________________________ 2. Ventricular diastole is ____________________________________________________________________________ 3. Atrial diastole is ________________________________________________________________________________ 4. Ventricular systole is _____________________________________________________________________________ 5. When the atria of the heart contract, the ventricles ______________________________________________________ 6. When the ventricles of the heart contract, the atria ______________________________________________________ B. Cardiac Cycle 1. During a cardiac cycle, the pressure within the heart chambers______________________________which is what causes the valves to _________________________________________________________________________________________ 2. The pressure in the ventricles is low during ___________________________________________________________ 3. During diastole, the A-V valves are _________________________________________________________________ 15-2 4. About _________________________________________ % of the blood flows passively from the atria into ventricles and the remaining blood is pushed into the ventricles when the _______________________________________________ 5. As ventricles contract, the A-V valves _______________________________________________________________ 6. When the pressure in the atria is lower than venous pressure, blood flows from ______________________ into _______________________________________________________________________ 7. During ventricular systole, ventricular pressure increases and the______________________________valves open. 8. As blood flows out of the ventricles, ventricular pressure _________________________________________________ 9. The semilunar valves close when ___________________________________________________________________ C. Heart Sounds 1. Heart sounds are produced by ______________________________________________________________________ 2. The first heart sound is ____________ and occurs during______________________________when _______________ 3. The second heart sound is ___________ and occurs during______________________________when______________ 4. A murmur is ___________________________________________________________________________________ D. Cardiac Muscle Fibers 1. A functional syncytium is _________________________________________________________________________ 2. Two syncytiums of the heart are ____________________________________________________________________ 3. The atrial syncytium and ventricular syncytium are connected by __________________________________________ E. Cardiac Conduction System 1. The cardiac conduction system is responsible for _______________________________________________________ 2. The S-A node is located______________________________and initiates ___________________________________ 3. The S-A node is called the pacemaker because _________________________________________________________ 4. As a cardiac impulse travels from the S-A node into the______________________________it goes from cell to cell via 5. Conducting fibers deliver impulses from the S-A node to the ______________________________________________ 6. The A-V node is located______________________________and Provides __________________________________ 7. Impulses are delayed as they move through the A-V node because__________________________________________ 8. From the A-V node, impulses pass to ________________________________________________________________ 9. The A-V bundle is located______________________________and gives rise to ______________________________ 10. Purkinje fibers carry impulses _____________________________________________________________________ 11. The ventricular myocardium contracts as ____________________________________________________________ 12. Purkinje fibers are located ________________________________________________________________________ 13. The ventricular walls contract with a twisting motion because ____________________________________________ 14. Contraction of the ventricles begins at the apex of the heart and pushes blood______________________________ F. Electrocardiogram 1. An electrocardiogram is __________________________________________________________________________ 2. An ECG is recorded by ___________________________________________________________________________ 3. A P-wave is produced when _______________________________________________________________________ 4. A QRS-wave is produced when_____________________________________________________________________ 5. A T-wave is produced when _______________________________________________________________________ 6. Physician’s use ECG patterns to ____________________________________________________________________ G. Regulation of Cardiac Cycle 1. The volume of blood pumped changes to accommodate __________________________________________________ 2. The parasympathetic nerve to the heart is the ______________________________________________________ nerve 3. The vagus nerve innervates the ________________________________________________________________ nodes. 4. The vagus nerve can alter heart rate by _______________________________________________________________ 5. Sympathetic fibers reach the heart via the ________________________________________________________ nerves. 6. The endings of accelerator nerves secrete______________________________which increases ___________________ 15-3 7. The cardiac control center controls __________________________________________________________________ 8. Baroreceptors detect _____________________________________________________________________________ 9. When baroreceptors in the aorta detect and increase in pressure, they signal the______________________________ 10. If blood pressure is too high, the medulla oblongata sends______________________________to the heart to heart rate. 11. If venous blood pressure increases abnormally, ______________________________ impulses flow to the heart and heart rate and contraction ________________________________________________________________________________ 12. Rising body temperature ________________________________________________________________ heart action. 13. The most important ions that influence heart action are _________________________________________________ IV. Blood Vessels A. Introduction 1. Blood vessels form a closed ____________ that carries blood _____________________________________________ 2. Five types of blood vessels are _____________________________________________________________________ 3. ______________________________conduct blood away from the heart and to______________________________ 4. ________________________________________________________ conduct blood from capillaries and to the heart. 5. The capillaries are sites of _________________________________________________________________________ B. Arteries and Arterioles 1. Arteries are______________________________that are adapted for________________________________________ 2. Arteries give rise to ______________________________________________________________________________ 3. The three layers of the wall of an artery are ___________________________________________________________ 4. The inner layer of an artery is called______________________________and functions to _______________________ 5. The middle layer of an artery is called______________________________andis composed of ___________________ 6. The outer layer is______________________________andconsists of _______________________________________ 7. The vasa vasorum of an artery is ____________________________________________________________________ 8. The______________________________nervous system innervates smooth muscle inarteries and arterioles. 9. Vasomotor fibers stimulate______________________________to contract,_______________the diameter of the vessel. 10. Vasoconstriction is _____________________________________________________________________________ 11. Vasodilation is______________________________________________________________________________ and occurs when ______________________________________________________________________________________ 12. Changes in the diameters of arteries and arterioles greatly influence _______________________________________ 13. The wall of a very small arteriole consists of _________________________________________________________ 14. Metarterioles are______________________________andhelp regulate _____________________________________ 15. Arteriovenous shunts are _________________________________________________________________________ C. Capillaries 1. Introduction a. The smallest diameter blood vessels are _____________________________________________________ b. Capillaries connect _____________________________________________________________________ c. The wall of a capillary consists of __________________________________________________________ 2. Capillary Permeability a. The most permeable capillaries are located ___________________________________________________ b. Protective and tight capillaries are located ____________________________________________________ 3. Capillary Arrangement a. The_______________________________________________________ , the denser its capillary networks. b. Tissues richly supplied with capillaries are ___________________________________________________ c. Tissues that lack capillaries are ____________________________________________________________ d. During exercise, blood is directed to __________________________ and it bypasses _________________ 4. Regulation of Capillary Blood Flow a. Precapillary sphincters are located______________________________and their function is_____________ 15-4 b. When cells have______________________________,precapillary sphincters relax and blood flow _______ 5. Exchanges in the Capillaries a. The vital function of______________________________occurs in the capillaries. b. Biochemicals move through capillary walls by ________________________________________________ c. ______________________________________________________ is the most important means of transfer. d. Oxygen and nutrients diffuse out of the capillary walls into surrounding cells because _________________ _______________________________________________________________________________________ e. Carbon dioxide and other wastes diffuse into the capillary blood because______________________________ f. Plasma proteins generally remain in the blood because __________________________________________ g. In filtration, hydrostatic pressure ___________________________________________________________ h. In the capillaries, the force for filtration is provided by __________________________________________ i. Blood pressure is greater at the ______________________________________________ end of the capillary. j. Colloid osmotic pressure is______________________________and is created by______________________________in the blood of capillaries. k. At the arteriolar end of the capillary, _____________________________________________ predominates. l. At the venular end of the capillary, _______________________________________________ predominates. D. Venules and Veins 1. Venules are ___________________ that continue from ______________________________and merge to form _____ 2. The middle layer of the wall of a vein is______________________________compared to that of an artery. 3. The function of valves in veins is ___________________________________________________________________ 4. Veins also function as blood _______________________________________________________________________ V. Blood Pressure A. Introduction 1. Blood pressure is ________________________________________________________________________________ 2. Blood pressure most commonly refers to _____________________________________________________________ B. Arterial Blood Pressure 1. Systolic pressure is______________________________and is created when _________________________________ 2. Diastolic pressure is______________________________andis created when _________________________________ 3. A pulse is______________________________________________________________________________________ 4. Common places to detect a pulse are _________________________________________________________________ C. Factors that Influence Arterial Blood Pressure 1. Heart Action a. Stroke volume is _______________________________________________________________________ b. Cardiac output is _______________________________________________________________________ c. If stroke volume or heart rate increases, cardiac output __________________________________________ 2. Blood Volume a. Blood volume equals ____________________________________________________________________ b. Blood pressure is __________________________________________________________ to blood volume. 3. Peripheral Resistance a. Peripheral resistance is___________________________________________________________________ b. If peripheral resistance increases, blood flow_______________________and blood pressure ____________ c. Dilation of blood vessels, ________________________________________________ peripheral resistance. 4. Viscosity a. Viscosity is ___________________________________________________________________________ b. As blood viscosity rises, blood pressure _____________________________________________________ c. ______________________________________________________________ contribute to blood viscosity. D. Control of Blood Pressure 15-5 1. Blood pressure is determined by ____________________________________________________________________ 2. Cardiac output depends on ________________________________________________________________________ 3. Stroke volume is the difference between ______________________________________________________________ 4. End Diastolic Volume is __________________________________________________________________________ 5. End Systolic Volume is ___________________________________________________________________________ 6. Factors affecting stoke volume and heart rate are _______________________________________________________ 7. Preload is______________________________________________________________________________________ 8. The greater the EDV, the greater the _________________________________________________________________ 9. Starling’s Law of the Heart is the relationship _________________________________________________________ 10. The more blood that enters the heart, the greater the ____________________________________________________ 11. The less blood that returns from veins to the heart, the less _______________________________________________ 12. Starling’s Law of the Heart ensures _________________________________________________________________ 13. If blood pressure rises, ____________ initiate the_______________________ reflex which________ blood pressure. 14. If blood pressure falls, the___________________reflex occurs which_______________increases __________________, which increases______________________________, which______________________________blood pressure. 15. Other factors that increase heart rate and blood pressure are ______________________________________________ 16. When arterial blood pressure suddenly increases, baroreceptors signal______________________________and sympathetic outflow to arterial walls______________________________which results in ___________________________________ 17. Chemicals that influence peripheral resistance are _____________________________________________________ E. Venous Blood Flow 1. Blood pressure____________________________________________________ as the blood moves through the arterial system into _______________________________________________________________________________________ 2. Blood flow through the venous system largely depends on ________________________________________________ 3. The ______________________ of skeletal muscles helps push______________________________toward the heart. 4. During inspiration, the pressure in the thoracic cavity______________________________and the pressure in the abdominal cavity ___________________________________________________________________________________________ 5. An increase in abdominal pressure will squeeze blood ___________________________________________________ 6. When venous pressure is __________________________________________________ sympathetic reflexes stimulate ________________________________________________________________________________________________ F. Central Venous Pressure 1. Central venous pressure is _________________________________________________________________________ 2. Central venous pressure is of special interest because ____________________________________________________ 3. Other factors that increase central venous pressure are ___________________________________________________ 4. An increase in central venous pressure can lead to ______________________________________________________ VII. Paths of Circulation A. Introduction 1. The two major pathways of blood vessels are __________________________________________________________ 2. The pulmonary circuit consists of ___________________________________________________________________ 3. The systemic circuit carries ________________________________________________________________________ B. Pulmonary Circuit 1. Blood enters the pulmonary circuit as it ______________________________________________________________ 2. The pulmonary trunk divides into ___________________________________________________________________ 3. Within the lungs the pulmonary arteries divide into _____________________________________________________ 4. The lobar branches give rise to _____________________________________________________________________ 5. The blood in the arteries and arterioles of the pulmonary circuit is low in__________and high in __________________ 6. Gases are exchanged between ______________________________________________________________________ 7. The arterial pressure in the pulmonary circuit is less than in the systemic circuit because ________________________ 15-6 8. _______________________________________________________________ removes any that gets into the alveoli. 9. Blood entering the venules of the pulmonary circuit is_____________rich and low in _________________________ 10. Venules merge to form ___________________________________________________________________________ 11. __________________________________________________________________ return blood to the left atrium and this completes_____________________________________________________________________________________ C. Systemic Circuit 1. Freshly oxygenated blood moves from the left atrium to _________________________________________________ 2. Contraction of the left ventricle forces _______________________________________________________________ 3. The systemic circuit includes ______________________________________________________________________ VIII. Arterial System A. Introduction 1. The _________ is the largest diameter artery in the body. 2. The aorta extends ______________________, arches over ________________________, and descends ____________________________________________________________ B. Principal Branches of the Aorta 1. The ascending aorta is ____________________________________________________________________________ 2. An aortic sinus is ________________________________________________________________________________ 3. ________________________________________________________________________ arise from the aortic sinus. 4. Aortic bodies are______________________________and contain _________________________________________ 5. Three arteries originating from the aortic arch are _______________________________________________________ 6. The brachiocephalic artery supplies _________________________________________________________________ 7. The brachiocephalic divides into ____________________________________________________________________ 8. The common carotids supply_______________________________________________________________________ 9. The subclavian arteries supply _____________________________________________________________________ 10. The descending aorta moves ______________________________________________________________________ 11. The thoracic aorta is ____________________________________________________________________________ 12. Branches of the thoracic aorta are __________________________________________________________________ 13. The abdominal aorta is __________________________________________________________________________ 14. Branches of the abdominal aorta are ________________________________________________________________ C. Arteries of the Neck, Head, and Brain 1. Branches of______________________________supply structures within the neck, head, and brain. 2. The main divisions of the subclavian artery to the neck, head, and brain are __________________________________ 3. The common carotid artery communicates with these regions by ___________________________________________ 4. The vertebral arteries arise from______________________________and supply ______________________________ 5. A basilar artery is formed by _______________________________________________________________________ 6. The basilar artery divides into______________________________that supply ________________________________ 7. The cerebral arterial circle is formed by ______________________________________________________________ 8. Functions of the cerebral arterial circle are ____________________________________________________________ 9. Thyrocervical arteries give rise to ___________________________________________________________________ 10. Costocervical arteries carry blood to ________________________________________________________________ 11. The common carotid arteries ascend ________________________________________________________________ 12. The external carotid artery gives off branches to _______________________________________________________ 13. Main branches of external carotid arteries are _________________________________________________________ 14. The superior thyroid artery supplies ________________________________________________________________ D. Arteries to the Shoulder and Upper Limb 1. As it passes into the arm, the subclavian artery becomes the _______________________________________________ 2. The axillary artery supplies ________________________________________________________________________ 3. The axillary artery becomes the_____________________________________________________________________ 15-7 4. The brachial artery gives rise to ____________________________________________________________________ 5. The branches of the brachial artery supplies ___________________________________________________________ 6. Within the elbow, the brachial artery divides into _______________________________________________________ 7. The branches of the ulnar artery supply_______________________________________________________________ 8. The branches of the radial artery supply ______________________________________________________________ 9. Blood supply to the wrist, hands, and fingers come from _________________________________________________ E. Arteries to the Thoracic and Abdominal Walls 1. The internal thoracic artery is a branch of _____________________________________________________________ 2. The internal thoracic artery gives off two ________________________________________________________ to each 3. The anterior intercostals arteries supply ______________________________________________________________ 4. The posterior intercostals arteries arise from______________________________and enter ______________________ 5. The posterior intercostals arteries supply _____________________________________________________________ 6. Branches of the internal thoracic and external iliac arteries provide blood to __________________________________ 7. Phrenic and lumbar arteries supply __________________________________________________________________ F. Arteries to the Pelvis and Lower Limb 1. The abdominal aorta divides to form _________________________________________________________________ 2. The common iliac arteries provide blood to ___________________________________________________________ 3. Each common iliac divides into_____________________________________________________________________ 4. The internal iliac artery gives off branches to __________________________________________________________ 5. Branches of the internal iliac artery are _______________________________________________________________ 6. The iliolumbar arteries supply ______________________________________________________________________ 7. Superior and inferior gluteal arteries supply ___________________________________________________________ 8. Internal pudendal arteries supply ____________________________________________________________________ 9. Superior and inferior vesical arteries supply ___________________________________________________________ 10. Middle rectal arteries supply ______________________________________________________________________ 11. Uterine arteries supply___________________________________________________________________________ 12. The external iliac artery provides the main blood supply to ______________________________________________ 13. Two branches of the external iliac artery are __________________________________________________________ 14. The inferior epigastric artery and deep circumflex artery supply___________________________________________ 15. The external iliac artery becomes the _______________________________________________________________ 16. The femoral artery gives off branches to _____________________________________________________________ IX. Venous System A. Characteristics of Venous Pathways 1. The vessels of the venous system begin with __________________________________________________________ 2. Venous pathways are hard to follow because __________________________________________________________ 3. The larger veins typically parallel ___________________________________________________________________ 4. The veins from most body parts converge into _________________________________________________________ B. Veins from the Brain, Head, and Neck 1. The external jugular veins drain blood from ___________________________________________________________ 2. The external jugular veins empty into ________________________________________________________________ 3. The internal jugular veins arise from _________________________________________________________________ 4. The brachiocephalic veins are formed from ___________________________________________________________ 5. The brachiocephalic veins merge to give rise to ________________________________________________________ C. Veins from the Upper Limb and Shoulder 1. A set of ___________________ and _________________________________________________ drain the upper limb. 2. The deep veins generally parallel ___________________________________________________________________ 3. The superficial veins connect ______________________________________________________________________ 15-8 and also communicate with _________________________________________________________________________ 4. The main vessels of the superficial network are ________________________________________________________ D. Veins from the Abdominal and Thoracic Walls 1. Tributaries of______________________________drain the abdominal and thoracic walls. 2. The azygos vein originates in _____________________________________________________________ and ascends 3. The azygos vein drains ___________________________________________________________________________ 4. Tributaries of the azygos vein include ________________________________________________________________ 5. The superior and inferior hemiazygos veins drain _______________________________________________________ 6. The ascending lumbar veins drain ___________________________________________________________________ E. Veins from the Abdominal Viscera 1. Veins carry blood directly to the atria of the heart, except those of __________________________________________ 2. The hepatic portal veins drains______________________________and carries blood to the______________________ 3. The hepatic portal system is _______________________________________________________________________ 4. Tributaries of the hepatic portal system include ________________________________________________________ 5. The gastric veins drain the_________________________________________________________________________ 6. Superior mesenteric veins drain the __________________________________________________________________ 7. Splenic veins drain ______________________________________________________________________________ 8. The blood flowing to the liver in the hepatic portal system is _________poor and ___________________________ rich. 9. The liver ____________________________________________________________________________ the nutrients. 10. Kupffer cells are located _________________________________________________________________________ 11. Blood leaves the liver through _____________________________________________________________________ 12. Hepatic veins empty blood into ____________________________________________________________________ 13. Veins that empty into the inferior vena cava are _______________________________________________________ F. Veins from the Lower Limb and Pelvis 1. Veins that drain the lower limb can be divided into _____________________________________________________ 2. The deep veins of the leg have names that correspond to _________________________________________________ 3. The popliteal vein is formed from ___________________________________________________________________ 4. The femoral vein originates from ___________________________________________________________________ 5. The external iliac vein originates from _______________________________________________________________ 6. The small saphenous vein begins in______________________________and passes ____________________________ 7. The small saphenous vein ascends______________________________and joins the___________________________ 8. The great saphenous vein originates on_____________and ascends________and eventually joins the ______________ 9. The longest vein of the body is _____________________________________________________________________ 10. The saphenous veins communicate with _____________________________________________________________ X. Life-Span Changes 1. _____________________________________ of men over the age of sixty have at least one narrowed coronary artery. 2. Some degree of______________________________deposition in blood vessels may be part of normal aging. 3. During exercise, _________________________________________________________________ decreases with age. 4. _________________________________________________________________ may cause enlargement of the heart. 5. The number of _________________ in the heart fall and______________________________increases. 6. With age, heart valves begin to _____________________________________________________________________ 7. Systolic blood pressure ____________________________________________________________________ with age. 8. The increase in systolic blood pressure is due to ________________________________________________________ 9. Resting heart rate_________________________________________________________________________ with age. 10. With age, changes in arteries include _______________________________________________________________ 11. The number of capillaries _________________________________________________________________ with age. 12. ________________________________________________________ can help maintain a “young” vascular system. 15-9