UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
Table of Contents
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
Page 1 of 7
2
2
2
3
3
4
4
4
5
5
6
6
6
7
7
7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
1.
Chemical Product
Product Name: Sterile Water for Injection
Chemical name: Not applicable
Synonyms: Not applicable
Chemical Formula: H2O
2.
Composition and Information on Ingredients
Composition: Water for Injection
Toxicological Data on Ingredients: Not applicable
3.
Hazards Identification
Potential Acute Health Effects: Not applicable
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not applicable
MUTAGENIC EFFECTS: Not applicable
TERATOGENIC EFFECTS: Not applicable
DEVELOPMENTAL TOXICITY: Not applicable
Page 2 of 7
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
4.
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
First Aid Measures
General measures: First Aid is not usually required since it is not likely to cause irritation,
but if necessary take selective measures.
Skin contact: Wash with soap and water and seek medical attention if irritation persists.
Serious skin contact: Not known to be absorbed through the skin.
Eye contact: Flush eyes with water for 15 minutes and seek medical attention if irritation
persists.
Ingestion: Induce vomiting only if victim is conscious.
Serious ingestion: Seek medical attention if adverse effects occur.
Inhalation: Remove victim to fresh air and apply artificial respiration if needed.
Serious inhalation: Not applicable
5.
Fire and Explosion Data
Flammability of the Product: Non-Flammable
Auto-Ignition Temperature: Not applicable
Flash points: Not applicable
Flammable limits: Non-flammable
Products of Combustion: Not applicable
Fire Hazards in Presence of Various Substances: Not applicable
Explosion Hazards in Presence of Various Substances: Not applicable
Page 3 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
Fire fighting media and Instructions: Not applicable
Special Remarks on Fire Hazards: Not applicable
Special Remarks on Explosion Hazards: Not applicable
6.
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Small spill: Wipe up with damp cloth and place in container for disposal
Large spill: Absorb liquid with clay absorbent and absorbent pads or paper towels.
7.
Handling and Storage
Precautions: avoid all contact and inhalation of mists or vapours associated with the product.
Storage: Must be stored in tightly closed containers in a cool dry place which is well
ventilated.
8.
Exposure Controls/Personal Protection
Airborne Exposure Limits: Not applicable
Engineering Controls: Provide adequate ventilation
Personal Protection: Not applicable
Page 4 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
9.
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
Physical and Chemical Properties
Physical state and appearance: Liquid, Clear, Colourless solution
Odour: Not applicable
Taste: Not applicable
Molecular Weight: 18.02g
pH (1% solution/water): 5.0 to 7.0
Boiling Point: 100°C
Melting Point: 0°C
Critical Temperature: 374°C
Specific Gravity (Water = 1): 1.0
Vapour Pressure (mmHg): 17.5 mmHg (20°C)
Vapour Density: Not applicable
Volatility: 0%
Odour Threshold: Not applicable
Water/Oil Distribution Coefficient: Not applicable
Ionicity (in Water): Not applicable
Dispersion Properties: Not applicable
Solubility: Miscible
10.
Stability and Reactivity Data
Stability: Stable
Corrosivity: Not applicable
Instability temperature: Not applicable
Conditions of Instability: Avoid heat, light and humidity, and keep away from flames since
water will boil off to form water vapour.
Incompatibles: Will react with sodium and potassium metal leading to the electrolysis of
water to form the explosive hydrogen and oxygen.
Polymerization: Not applicable
Page 5 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
11.
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
Toxicological Information
Toxicity to animals:
Oral LD50: >90 mL/kg [Rat]
Intravenous LD50: 25 g/kg [Mouse]
Intraperitoneal LD50: 190 g/kg [Mouse]
Effects on humans:
Acute potential health effects: Not applicable
Chronic potential health effects:
MUTAGENIC EFFECTS: Not applicable
TERATOGENIC EFFECTS: Not applicable
DEVELOPMENTAL TOXICITY: Not applicable
Other information: Used as a diluent
12.
Ecological Information
Ecotoxicity: No harmful effects to aquatic organisms are expected.
13.
Disposal Considerations
Waste Disposal: What is not recycled must be handled as hazardous waste and sent to an
approved incinerator or disposed in an approved waste facility. Dispose in the container
marked NON-HAZARDOUS WASTE.
Page 6 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
WATER FOR INJECTION
14.
15.
Ref. No.
MSDS /PD/26_01
Valid for:
2 years from approval
References
-
Pfizer. Material Safety Data Sheet. [Online]. 2012 [cited 2013 Oct 8]. Available from:
URL: http://www.pfizer.com/files/products/material_safety_data/EX02902.pdf
-
Lutipold Pharmaceuticals. Sterile Water for Injection, USP. Material Safety Data
Sheet. [Online]. 2010 [cited 2013 Oct 8]. Available from: URL:
http://www.americanregent.com/documents/product51msds.pdf
-
Material Safety Data Sheet. Vedco Sterile Water for Injection250ml. [Online]. [cited
2013 Oct 8]. Available from: URL: http://www.pattersonvet.com/msds/078783990
-
Nova-Tech Pure Performance. Safety data Sheet. Sterile Water for Injection.
[Online].
2012
[cited
2013
Oct
8].
Available
from:
URL:
http://www.vedco.com/images/MSDS/Sterile%20Water%20for%20Inj.pdf
-
Critical Temperature and Pressure. [Online]. [cited 2013 Oct 8]. Available from:
URL: http://www.chem.purdue.edu/gchelp/liquids/critical.html
Appendices
Not applicable
16.
Revision History
Version Number
Amendments/ Reasons for change
01
Initial Release
Page 7 of 7