UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Table of Contents
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
1.
Chemical Product
Product Name: Phenolphthalein
Chemical name: Not Applicable
Synonyms:
Phenolphthalein
indicator;
3,3-Bis(4-Hydoroxyphenyl)-1(3H)Isobenzofuranone;
3,3-Bis(p-Hydroxyphenyl)Phthalide;
Alpha-Di(p
Hydroxyphenyl)phthalide
Chemical Formula: C20H14O4
2.
Composition and Information on Ingredients
Composition: Phenolphthalein
Toxicological Data on Ingredients: Not Applicable
3.
Hazards Identification
Potential Acute Health Effects: May cause eye, skin, gastrointestinal and respiratory tract
irritation.
Harmful
if
swallowed
since
ingestion
may
cause
fever,
blood pressure increase and other unspecified vascular effects.
Potential Chronic Health Effects: May cause kidney injury
CARCINOGENIC EFFECTS: Limited evidence
MUTAGENIC EFFECTS: Not Applicable
TERATOGENIC EFFECTS: Not Applicable
DEVELOPMENTAL TOXICITY: Not Applicable
4.
First Aid Measures
General measures:
Skin contact: Remove any contaminated clothing prior to flushing skin with plenty of soap
and water.
Page 2 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
Serious skin contact: Not Applicable
Eye contact: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Seek medical attention.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Seek medical
attention if irritation or symptoms occur.
Serious ingestion: Not Applicable
Inhalation: Remove to fresh air immediately. If not breathing, give artificial respiration and
if breathing is difficult, give oxygen. Seek medical attention if cough or other symptoms
appear.
Serious inhalation: Not Applicable
5.
Fire and Explosion Data
Flammability of the Product: Not Applicable
Auto-Ignition Temperature: Not Applicable
Flash points: Not Applicable
Flammable limits: Not Applicable
Products of Combustion: Not Applicable
Fire Hazards in Presence of Various Substances: Not Applicable
Explosion Hazards in Presence of Various Substances: Not Applicable
Fire fighting media and Instructions: Wear a self-contained breathing apparatus and full
protective gear. For small fires, use water spray, dry chemical, carbon dioxide or chemical
foam.
Special Remarks on Fire Hazards: Not Applicable
Page 3 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
Special Remarks on Explosion Hazards: Not Applicable
6.
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Spills: Clean up immediately by sweeping up and absorbing the spills with absorbent
(vermiculite, sand, fuller's earth), ensuring that the generation of dust is avoided and
ventilation is provided.
7.
Handling and Storage
Precautions: Use with adequate ventilation and minimise dust generation and accumulation.
Avoid contact with eyes, skin, and clothing.
Storage: Keep container closed and store in a cool, dry, well-ventilated area away from
incompatible substances.
8.
Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Applicable
Engineering Controls: Good general ventilation should be sufficient to control airborne
levels. An eyewash facility and a safety shower should be available.
Personal Protection: Wear appropriate protective eyeglasses or chemical safety goggles,
appropriate gloves, appropriate protective clothing to prevent skin exposure and an
approved respirator when necessary.
9.
Physical and Chemical Properties
Physical state and appearance: Pale yellow solid
Odour: Odourless
Taste: Not Applicable
Molecular Weight: 318.1g
pH (5% solution/water): Not Applicable
Boiling Point: Not Applicable
Melting Point: 264°C
Critical Temperature: Not Applicable
Page 4 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
Specific Gravity (Water = 1): 1.3
Vapour Pressure (mmHg): Negligible
Vapour Density: Not Applicable
Volatility: Not Applicable
Odour Threshold: Not Applicable
Water/Oil Distribution Coefficient: Not Applicable
Ionicity (in Water): Not Applicable
Dispersion Properties: Not Applicable
Solubility: Insoluble in water
10.
Stability and Reactivity Data
Stability: Stable under normal temperatures and pressures up to boiling point.
Corrosivity: Not Applicable
Instability temperature: Not Applicable
Conditions of Instability: Incompatible materials, dust generation, excess heat
Incompatibles: Strong oxidizing agents
Polymerization: Not Applicable
11.
Toxicological Information
Toxicity to animals: Not Applicable
Effects on humans:
Acute potential health effects: May cause eye, skin, gastrointestinal and respiratory tract
irritation.
Harmful
if
swallowed
since
ingestion
may
cause
fever,
blood pressure increase and other unspecified vascular effects.
Chronic potential health effects: May cause kidney injury
MUTAGENIC EFFECTS: Not Applicable
TERATOGENIC EFFECTS: Not Applicable
Page 5 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
DEVELOPMENTAL TOXICITY: Not Applicable
Other information: Not Applicable
12.
Ecological Information
Ecotoxicity: Not Applicable
13.
Disposal Considerations
Waste Disposal: What is not recycled must be handled as hazardous waste and sent to an
approved incinerator or disposed in an approved waste facility. Dispose of in the hazardous
waste container marked WATER INSOLUBLE, NON HALOGENATED WASTE.
14.
References
- Acros Organics. Material Safety Data Sheet; Phenolphthalein. [online]. 2007 [cited
2014
Jan
9].
Available
from:
URL:
http://www.ch.ntu.edu.tw/~genchem99/msds/exp14/phenolphthalein.pdf
-
Material Safety Data Sheet; Phenolphthalein. [online]. 2000 [cited 2014 Jan 9].
Available from: URL: http://avogadro.chem.iastate.edu/msds/phenolphthalein.htm
-
Material Safety Data Sheet; Phenolphthalein. [online]. 2004 [cited 2014 Jan 9].
Available from: URL: http://www.myerstest.com/images/Phenolphthalein_MSDS.pdf
Page 6 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PHENOLPHTHALEIN
Ref. No.
MSDS /PD/42_01
Valid for:
2 years from approval
15.
Appendices
Not applicable
16.
Revision History
Version Number
Amendments/ Reasons for change
01
Initial Release
Page 7 of 7