UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Table of Contents
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
1.
Chemical Product
Product Name: Propanol
Chemical name: 1-Propanol
Synonyms: n-Propyl alcohol; Propylic alcohol; Ethyl-carbinol
Chemical Formula: CH3CH2CH2OH
2.
Composition and Information on Ingredients
Composition:
Toxicological Data on Ingredients:
ORAL (LD50):
Acute: 1870 mg/kg [Rat.].
6800 mg/kg [Mouse].
DERMAL (LD50):
Acute: 4060 mg/kg [Rabbit.].
VAPOR (LC50): Acute: 67882.3 ppm 4 hour(s) [Mouse].
3.
Hazards Identification
Potential Acute Health Effects: Very hazardous in case of eye contact (irritant), skin
contact (irritant, permeator), ingestion and inhalation.
Potential Chronic Health Effects: May lead to dermatitis
CARCINOGENIC EFFECTS: Not Applicable
MUTAGENIC EFFECTS: Have occurred in microorganisms
TERATOGENIC EFFECTS: Have occurred in experimental animals
DEVELOPMENTAL TOXICITY: Not Applicable
Page 2 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
4.
First Aid Measures
General measures:
Skin contact: Immediately wash with plenty of water and non-abrasive soap and afterwards
cover the irritated skin with an emollient. If irritation persists, seek medical attention.
Serious skin contact: Wash with a disinfectant soap and cover the contaminated skin with
an anti-bacterial cream. Seek immediate medical attention.
Eye contact: Remove any contact lenses and immediately flush eyes with running water for
at least 15 minutes, keeping eyelids open. Seek medical attention.
Ingestion: Loosen tight clothing such as a collar, tie, belt or waistband. Do not induce
vomiting. Seek immediate medical attention.
Serious ingestion: Not Applicable
Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical
attention.
Serious inhalation: Loosen tight clothing such as a collar, tie, belt or waistband and move
the victim to a safe area as soon as possible. If breathing is difficult, administer oxygen and if
the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical attention.
5.
Fire and Explosion Data
Flammability of the Product: Flammable
Auto-Ignition Temperature: 371°C (699.8°F)
Flash points:
CLOSED CUP: 15°C (59°F)
OPEN CUP: 27.2°C (81°F)
Flammable limits:
LOWER: 2.1%
UPPER: 13.5%
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Highly flammable in the presence of
open flames and sparks, heat, and oxidising materials.
Explosion Hazards in Presence of Various Substances: Not Applicable
Fire fighting media and Instructions: Use dry chemical powder for small fire and alcohol
foam, spray or fog for large fire.
Special Remarks on Fire Hazards: When vapour is exposed to flame or heat it may travel a
considerable distance to source of ignition and flash back. When heated to decomposition it
emits acrid smoke and irritating fumes. CAUTION: MAY BURN WITH NEAR INVISIBLE
FLAME
Special Remarks on Explosion Hazards: Not Applicable
6.
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Small Spill: Dilute with water and mop up or absorb with an inert dry material.
Large Spill: Stop leak if without risk by absorbing with DRY earth, sand or other noncombustible material.
7.
Handling and Storage
Precautions: Keep away from sources of ignition such as heat and incompatibles. Wear
appropriate respirator in case of poor ventilation.
Storage: Keep in a tightly closed container which is stored in a cool, well-ventilated area
separate from sources of ignition.
Page 4 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
8.
Exposure Controls/Personal Protection
Airborne Exposure Limits:
TWA: 200 STEL: 250 (ppm) from ACGIH (TLV) [1995]
TWA: 492 STEL: 614 (mg/m3) from ACGIH [1995]
Engineering Controls: Provide exhaust ventilation and ensure that eyewash stations and
safety showers are present.
Personal Protection: Wear splash goggles, lab coat, vapour respirator and gloves.
9.
Physical and Chemical Properties
Physical state and appearance: Colourless liquid
Odour: Alcohol-like
Taste: Not Applicable
Molecular Weight: 60.1 g
pH (5% solution/water): 7
Boiling Point: 97.22°C (207°F)
Melting Point: -126.2°C (-195.2°F)
Critical Temperature: Not Applicable
Specific Gravity (Water = 1): 0.8053 (Water = 1)
Vapour Pressure (mmHg): 14.9 mm of Hg (@ 20°C)
Vapour Density: 2.07 (Air = 1)
Volatility: Not Applicable
Odour Threshold: 5.3 ppm
Water/Oil Distribution Coefficient: LogP(oct)=0.25
Ionicity (in Water): Not Applicable
Dispersion Properties: Not Applicable
Solubility: Easily soluble in cold water, hot water, methanol, diethyl ether
10.
Stability and Reactivity Data
Stability: Stable under normal conditions of temperature and pressure
Corrosivity: Non-corrosive in presence of glass
Instability temperature: Not Applicable
Conditions of Instability: Heat, flames and sparks
Page 5 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
Incompatibles: Reactive with oxidising agents and acids
Polymerization: Not Applicable
11.
Toxicological Information
Toxicity to animals:
Acute oral toxicity (LD50): 1870 mg/kg [Rat.].
Acute dermal toxicity (LD50): 4060 mg/kg [Rabbit.].
Acute toxicity of the vapor (LC50): 67882.3 ppm 4 hour(s) [Mouse].
Effects on humans:
Acute potential health effects: Very hazardous in case of eye contact (irritant), skin contact
(irritant, permeator), ingestion and inhalation.
Chronic potential health effects: May lead to dermatitis
MUTAGENIC EFFECTS: Not Applicable
TERATOGENIC EFFECTS: Not Applicable
DEVELOPMENTAL TOXICITY: Not Applicable
Other information: Not Applicable
12.
Ecological Information
Ecotoxicity: Not Applicable
13.
Disposal Considerations
Waste Disposal: What is not recycled must be handled as hazardous waste and sent to an
approved incinerator or disposed in an approved waste facility. Dispose of container and
unused contents in accordance with local environmental control regulations.
Discard in a container marked WATER SOLUBLE NON-HALOGENATED WASTE.
Page 6 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
PROPANOL
Ref. No.
MSDS /PD/45_01
Valid for:
2 years from approval
14.
References
- ScienceLab.com. Material Safety Data Sheet; n-Propyl Alcohol. [online]. 2013 [cited
2014
Jan
23].
Available
from:
URL:
http://www.sciencelab.com/msds.php?msdsId=9924736
- Caledon Laboratory Chemicals. Material Safety Data Sheet; 1-Propanol. [online]. 2012
[cited
2014
Jan
23].
Available
from:
URL:
http://www.caledonlabs.com/upload/msds/8500-1e.pdf
15.
Appendices
Not applicable
16.
Revision History
Version Number
Amendments/ Reasons for change
01
Initial Release
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