CHEM 636 - SCHEDULE FOR LECTURES: (updated 3/21/2011)
Lecture #
Topic
1
W 1/19
Review of Fundamentals: Inorganic Reaction types; Reaction energetics;
2
F 1/21
Cont’d; worksheet
__________________________________________________________________________
3
M 1/24
Simple Associative Reactions: Lewis Acid/base adducts; Associative
reactions as in Ligand Substitution in Square Planar complexes
4
W 1/26
Cont’d. Nucleophilicity Scales; Nucleophilic Discrimination
Cont’d.
Time Scale Student project. Techniques for Monitoring Reaction Rates.
Water exchange in aqua complexes; Distinguishing features of A vs D, Ia and
Id pathways.
Simple to Complex Rate Expressions; Steady State approximation and
Competition Ratios
Activation Barriers: Arrhenius and Eyring Eqns
Ligand Substitution in Oh Complexes; Solvent Exchange and
Solvent/Medium Effects;
Redox Reactions; The Taube Experiment
Inner vs Outer Sphere Mechanisms for Electron Transfer.
Radical Chain Reactions in Inorganic/Organomet. Chemistry
Guest Lecturer- Francois Gabbai: Frustrated Lewis Pairs and Roles in
Catalysis
5
6
7
F 1/28
M 1/31
W 2/2
8
F 2/4
9
10
M 2/7
W 2/9
11
12
13
14
F
M
W
F
15
16
17
M 2/21
W 2/23
F 2/25
Organometallic Rxn Mech. Overview
Ox. Add’n/Reductive Elimination: Classic Halpern
Migratory Insertion: Classic Whitesides
18
19
20
M 2/28
W 3/2
F 3/4
Reactions at Metal Bound Ligands: Nucleophilic Attack at M-CO
Electrophilic Attack; Pi Complexes
MIDTERM EXAMINATION
21
M 3/7
22
23
W 3/9
F 3/11
Marcus Theory – Self Exchange Rates
Guest Lecturer: D.J. Darensbourg
Long Range Electron Transfer: D.J. Darensbourg
Fluxional Organometallics
M
3/14-18
SPRING BREAK
24
25
26
M 3/21
W 3/23
F 3/25
O.A./R.E.; Nuc. Displac; MCO Anions Nucleophilicity
C-H Bond Activation—Sam project
Insertion Mechanisms
27
28
29
M 3/28
W 3/30
F 4/1
Report for Classic Paper I (outside class)
Report for Classic Paper II (outside class)
Discussion in class.
2/11
2/14
2/16
2/18
CHEM 636 - SCHEDULE FOR LECTURES: (updated 3/21/2011)
30
M 4/4
31
32
33
34
35
W
F
M
W
F
4/6
4/8
4/11
4/13
4/15
Dawei – Kinetics and Mechanisms of Olefin insertion into M-H bonds JACS
1985, 107, 2670-2682.
CO/Olefin Copolymerization Catalysis: Andy
CO/Olefin Copolymerization Discussion
Vitamin B-12 Mechanism: Wan-Chum
Vitamin B-12 Discussion and other Bioinorganic Mechanisms
Reading Assignment
36
37
38
39
M
W
F
M
W
4/18
4/20
4/22
4/25
4/27
Randara – Carbonic Anhydrase:
Carbonic Anhydrase Discussion
READING DAY – NO CLASS
Nucleophilic attack on Metal-bound ligands
Selected Topics
40
F 4/29
Selected Topics in Catalysis
41
M 5/2
Selected Topics
42
T 5/3
5/10
(redefined day=F)
FINAL EXAM – 8:00 AM – 10:00 AM
CHEM 636 – Inorg. React. Mech.
Project Choices
Dawei Feng – Asymmetric Hydrogenation (Halpern Science)
Andrew Yeung – CO/Olefin Co-polymerization Catalysis
Wan-Chun Chung – The Mechanisms of Vitamin B12
Randara Pulukkody – Carbonic Anhydrase
Sam John Rajkumar – C-H Bond Activation