Oral Mycology lectuer (19) Dr.Baha,Hamdi.AL-Amiedie Ph.D.Microbiology Characteristic of fungi 1-• Eukaryotes 2- No chlorophyl (distinguishes them from plants and algae) 3- Unicellular to filamentous 4- Rigid cell wall 5-Spore bearing stages in the life cycle 6-Usually reproduce by sexual and asexual means 7-Insensitive to antibacterial antibiotics Comparising between fungi &Bacteria Cell wall structure of fungi Morphological types of fungi Three major groups 1. Moulds 2. Yeasts 3. Mushrooms Dimorphic fungi – fungi that have both a yeast stage and a mould stage In many cases vegetative cell of hypha contains more than one nucleus – typical hypha is a nucleated tube containing a cytoplasm ( a coenocytic) and no septa (cross walls) • Septate hyphae have one or two nuclei per cell Asexual spores Asexual reproduction Asexual spore formation: • chlamydospores (formed within sporangia) • conidia (formed naked at tips of hyphae) • budding (cell division) • fragmentation (of mycelium) Asexual spores Sexual spores Sexual spores are resistant to drying heating, freezing, and some chemical agents • Not as resistant to heat as are bacterial endospores • Either a sexual spore or an asexual spore can germinate and develop into a new hypha and Mycelium Sexual spore Fungal infection types 1-Rang from superfical infection to ovewhelming systemic infections that are rapidly fatal in the compromised host 2-they are increased in frequency as result of increased used of antibiotics Corticostroids& cytotoxic drugs 3-classified into superfical, cutaneous Subcutaneous&systemic infection;Systemic infection are subdivied into those caused by opportunistic fungi & by those caused by pathogenic fungi Oral Aspect of fungal infections Fungal infections in the oral and perioral regions occur either as primary localized lesions or as manifestations of systemic mycoses. By far the most common group of fungal infections that dental practitioners diagnose and treat are caused by Candida spp. Some of the rarer mycoses with oral manifestations