- Male Reproductive System Consists of the two testes (the male gonads), a system of genital ducts, the accessory glands, and the penis. 1-Testes Each testis is an oval structure housed in the separate compartment within the scrotum. It consists of highly tortuous seminiferous tubules that function in the production of spermatozoa. The lumen of each seminiferous tubule is lined by a seminiferous epithelium several cell layers thick. The basal cells of this epithelium are composed of Sertoli cells and spermatogonia. The latter cells divide by mitotic activity to replicate themselves and to produce primary spermatogonia. These dipliod primary spermatocytes enter the first meiotic division, forming secondary spermatocytes that, by completing the second meiotic division, give rise to haploid spermatids become spermatozoa, the male gamete. Small clumps of androgen producing endocrine cells, the interstitial cells of Leydig, these cells produce the male sex hormone testosterone. Prior to puberty, testosterone is not produce, but at the onset of puberty the pituitary gland releases luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Sp: spermatids, Sc : spermatocytes , Sm: sertoli nuclei , LC: leydig cells 2-genital ducts Epididymis Is consists of head , body and tail. AT: adipose t. , BV: blood vessel, C: cilia , CT: connective t., P: pigments 3- Accessory Glands A . Seminal Vesicles As the seminal vesicles, two highly convoluted tubular structures, join the ducts. The highly folded mucous membrane of the seminal vesicle is composed of a pseudostratified epithelium, whose columnar cells are interspersed with short basal cells, sitting on a fibroelastic lamina propria. The muscular coat is composed of inner circular and outer longitudinal layers of smooth muscle and is invested by a fibrous adventitia . MM: mucous membrane B. Prostate Gland The ejaculatory ducts join the urethra as these three structures traverse the substance of the prostate gland, whose capsule is composed of fibroelastic connective tissue and smooth muscle cells. The dense stroma of the gland is continuous with the capsule. The parenchyma of the prostate is composed of numerous individual glands disposed in three layers : mucosal, sub mucosal, and external (main). The lamina of these three groups drain into three system of ducts that lead into the expanded urethral sinus . The folded mucosa of the glands is composed of simple cuboidal to columnar epithelia supported by stroma , the ST: stroma , SM: smooth muscle ,PC: prostastic concretions, BV: Blood vessel lamina of the glands of older men posses round-to-ovoid proststic concretions .