HORSE H E A LT H L I N E S B r in g in g be t t e r h e a lt h to yo u r h o r ses DR. JENNY KELLY 2005-07 EHRF Research Fellow summer 2006 WESTERN COLLEGE OF VETERINARY MEDICINE • EQUINE HEALTH RESEARCH FUND Q I N S I D E 4 Lidocaine: Colic’s Damage Controller? Surgical specialists test the merits of lidocaine in colic surgery. 6 It’s in Your Genes 8 Horse Health, One Step (Stitch) at a Time 10 Equine Ed, Electronic Style 11 The Making of an Equine Veterinarian 12 The True View of Equine Anatomy 14 Program Brings Honours and Better Health to Horses Using genetic risk factors to identify high-risk endotoxemia patients. High-tech teaching tools help veterinary students learn about the horse. Q & A with veterinary graduate Tracy Epp of Boissevain, Man. The Equine Foundation of Canada donates $5,000 to WCVM. A new equine anatomy atlas gives readers a true view of the horse. EHRF introduces its new equine memorial program. FRONT COVER: EHRF Research Fellow Dr. Jenny Kelly listens in on a horse’s heart. Photo: Juliane Deubner. HOR S E H E A L TH L I N E S Horse Health Lines is produced by the Western College of Veterinary Medicine’s Equine Health Research Fund. Visit www.ehrf.usask.ca for more information. Please send comments to: Dr. Hugh Townsend, Editor, Horse Health Lines WCVM, University of Saskatchewan 52 Campus Drive, Saskatoon, SK S7N 5B4 Tel: 306-966-7453 • Fax: 306-966-7274 wcvm.research@usask.ca For article reprint information, please contact sm.ridley@sasktel.net. 2 H o r s e H e a l t h L i n e s • S u m m e r 2006 Do equine wound care products really work? Drs. Spencer Barber and James Carmalt, and Tyler Undenberg Wounds are a common occurrence in horses — and that’s why every tack and feed store in North America carries numerous equine wound care creams and gels on their shelves. While companies constantly promote these products, no firm can provide sound, scientific data to support their claims of efficacy. This summer, a team of WCVM scientists will evaluate some popular wound care products and determine which treatment results in the most rapid healing, the least amount of proud flesh, and the most durable repair with the most cosmetic appearance. As a first step, the surgical specialists will create standardized wounds (in size and location) on the legs and bodies of horses since there are key differences in how wounds heal in these areas. The research team will use general anesthesia while creating the skin-deep wounds, and all animals will receive pain control medication until all of the superficial wounds are completely healed. Researchers will treat the leg wounds with different wound care products: a topical hydrogel called Dermagel,® a ketanserin tartrate gel called Vulketan,® and platelet rich plasma therapy consisting of RemX,® Lacerum® and Lacerum II.® Clinicians will use the same three products to treat the body wounds as well as two other products: Preparation H® reportedly stimulated certain phases of healing in previous equine leg studies, while elk velvet antler is a non-commercial product that’s known to encourage wound healing. The research team will photograph each wound on a weekly basis to monitor the speed and type of healing. Once the wounds are completely healed, a scientist who is blinded to the treatment group will use image analysis software to measure and evaluate the wound areas. Results will provide horse owners with the first scientific data available about the efficacy of these wound care products. Q Can a hormone combination advance the breeding season in transitional mares? Drs. Claire Card and Tal Raz The natural breeding season for western Canadian horses arrives in May — but that’s not soon enough for many people in the region’s horse industry. Owners of performance horses often want to advance the breeding season so foals are born early or so they can complete embryo transfers ahead of show or racing seasons. Placing mares under artificial lighting has been shown to reactivate ovarian activity and speed up the breeding season. However, the practice is expensive and impractical since horses need to be stabled indoors for three months. As an alternative, WCVM scientists are investigating the use of hormonal therapies in transitional mares (mares with renewed ovarian activity). One hormonal therapy is deslorelin that’s available as Ovuplant® and as a compounded pharmaceutical product. Deslorelin works through the pituitary gland to stimulate the simultaneous secretion of two gonadotrophic hormones: follicle stimulating hormone and luteinizing hormone. Other researchers have reported that deslorelin hastens the first ovulation in mares during early and late transition, and that ovulation rates may improve if the treatment protocol includes human chorionic gonadotrophin (hCG) — a hormone that directly stimulates the dominant follicle. But so far, no one has examined the combined effect of deslorelin and hCG in transitional mares. This spring, Drs. Claire Card and Tal Raz will test this protocol on 15 mares and evaluate their progress in comparison to 10 mares that will The $60,000 Investment in Equine Health Western College of Veterinary Medicine scientists have received nearly $60,000 from the College’s Equine Health Research Fund to conduct four studies that will ultimately improve the health and care of horses around the world. receive no hormone treatment. The researchers will evaluate the combined effects of deslorelin and hCG on ovarian function, on the quality, size and viability of recovered embryos in transitional mares, and on the number of estrus cycles after treatment. If results indicate that the combined treatment protocol shows promise, this will be one of the first steps in developing a cheaper and less labourintensive alternative to preparing transitional mares for breeding outside of the normal season. Q Do genetic factors contribute to the development of sepsis in foals? Drs. Katharina Lohmann and Michelle Barton (University of Georgia) Neonatal sepsis, a systemic response to infection, is a major cause of disease and death in young foals. The condition causes young foals to develop clinical signs such as fever or hypothermia, irregular breathing and heart rate, and blood abnormalities. Sepsis develops because of an imbalance of the host’s pro- and anti-inflammatory responses. Cytokines such as tumour necrosis factor (TNF), which are produced by inflammatory cells in response to stimulation, are the mediators of these immune responses. Scientists have identified many risk factors for sepsis in young foals, but so far, no one has investigated the potential role of genetic risk factors. During the next two years, Dr. Katharina Lohmann of WCVM and Dr. Michelle Barton of the University of Georgia will investigate this possibility by comparing the frequency of genetic factors in about 100 septic and non-septic foals. Specifically, the researchers will collect DNA samples from all foals so they can measure the prevalence of single nucleotide polymorphisms (SNPs) in the equine TNF gene promoter. SNPs are stable gene sequence variations within a population that occur more frequently than random mutations. In the past few years, Lohmann has been studying the prevalence of SNPs and their biological significance in the development of diseases like equine endotoxemia and sepsis. The scientists will compare the frequency of SNPs in septic and nonseptic foals, and the frequency of SNPs between survivors and non-survivors of sepsis to assess a potential effect on disease outcome. The concentration of TNF in serum samples will also be compared between horses with and without SNPs to investigate whether the gene sequence variations may be associated with altered production of TNF. This is the first clinical evaluation of the role of gene polymorphisms in equine diseases, and results from this study will help to secure funding for larger scale clinical studies. By learning more about genetic risk factors and their role in the development of sepsis, scientists may eventually be able to identify foals at risk ahead of time and develop new strategies for preventing and treating the condition. Q Can georeferenced data help predict the risk of West Nile virus? Drs. Cheryl Waldner, Hugh Townsend and Tasha Epp (WCVM), and Dr. Olaf Berke (Ontario Veterinary College) Since the West Nile virus (WNV) spread to Saskatchewan in 2002, many horse owners have adopted costly vaccination programs and other preventive measures to minimize infection. But as researchers now understand, the risk of WNV infection varies in different geographic areas and changes over time. As horse owners’ level of interest in preventing this disease diminishes, more information is needed to direct efforts to monitor and control the virus’ impact on horses in Saskatchewan and in other parts of Western Canada. WCVM scientists have learned about the prevalence of WNV infection and disease in Saskatchewan horses through a large field study in 2003 and through the province’s continued surveillance of horses for clinical disease in 2005. All of this information, as well as data about climate, the virus’ prime vector (the Culex family of mosquitoes) and environment, have been referenced to geographic regions in Saskatchewan. During the next year, researchers from WCVM and the Ontario Veterinary College will combine all of this information with environmental and climate data collected from specialized satellites operated by NASA and other scientific centres. With the use of geographic information systems (GIS), the team can then develop a predictive map for the risk of WNV in Saskatchewan. By gaining a better understanding of where the risk of infection is diminished or elevated, scientists can identify specific areas in Saskatchewan where WNV surveillance and vaccination programs are needed. As well, the information will help to predict the risk of infection in future seasons and determine ways to consolidate surveillance programs. But the benefits go beyond predicting the risk of WNV infection: researchers can use this project as a useful model to develop surveillance and predictive modelling programs for other emerging diseases. Western College of Vet e r i n a r y Me d i c i n e 3 Lidocaine: Colic’s Damage Controller? The prognosis for all types of colic surgery has dramatically improved in the past 20 years, but horses that undergo surgery for small intestinal colic still have a 50-50 chance of survival. The main problem that faces surgical specialists during small intestinal colic surgery is having enough healthy intestinal tissue left to repair the damage caused by colic, explains Dr. Ryan Shoemaker of the Western College of Veterinary Medicine (WCVM). The surgical specialist and assistant professor in WCVM’s Department of Large Animal Clinical Sciences adds that small intestinal-related surgeries are more expensive than other types of colic surgeries. Besides trying to prevent further damage to the patient’s intestine during surgery, Shoemaker says surgeons need to determine which part of the intestine is healthy and safe to use and which part of the intestine is dead. And even if horses survive colic surgery, they still aren’t certain to recover. Post-operative complications such as ileus (partial or complete paralysis of the intestine) or intestinal adhesions (when the intestine abnormally attaches to itself or to other structures in the abdomen as a result of intestinal wall inflammation) can cause horses to colic once again — anywhere from seven days to six months after surgery. “Horses that develop post-operative intestinal adhesions can experience recurrent colic that may require additional surgery to deal with the problem,” says Dr. Jenny Kelly, a large animal surgical resident at WCVM. In some cases, adhesions forming after colic surgery can become so extensive that they can’t be corrected. Surgeons faced with this problem may be forced to euthanize a patient during surgery. “Even if we get the horses happy and healthy and leaving the hospital, adhesions could affect them later, so it’s not cut and dry,” points out Kelly. “We always make sure that owners are aware of the potential for more problems.” 4 H o r s e H e a l t h L i n e s • S u m m e r 2006 By Jessica Eissfeldt Surgical specialists use lidocaine as a local anesthetic during surgeries and as a nerve block in lameness tests — but can they rely on it for damage control after small intestinal colic surgery? A team of scientists at the Western College of Veterinary Medicine is striving to answer that very question. That’s where a WCVM research study on horses undergoing colic surgery comes into play. Supported by the Equine Health Research Fund, four scientists — Shoemaker and Kelly along with Drs. David Wilson and Andrew Allen — are determining whether intravenous (IV) administration of a drug called lidocaine can actually help to prevent intestinal adhesions after colic surgery. Lidocaine is commonly used as a local anesthetic and as a nerve block in lameness tests. It reduces pain, acts as an anti-inflammatory agent and also helps to maintain movement in a horse’s gut after colic surgery. What’s intriguing about lidocaine is its potential ability to prevent neutrophil-related intestinal damage after colic surgery. Neutrophils are the primary white blood cells that appear and invade the damaged intestine, causing swelling, inflammation and common complications like ileus and intestinal adhesions. Other researchers have reported that IV administration of lidocaine has decreased the migration of neutrophils and reduced the white blood cells’ adverse effects on tissue in humans and other species. “If we can keep the A SECOND FELLOW: The Equine Health Research Fund has selected large animal surgical resident Dr. Luca Panizzi as the second EHRF Research Fellow for 2006-07. Panizzi, who will begin his graduate studies program and residency at WCVM this summer, is a 2003 DVM graduate of the University of Parma, Italy. In April 2005, Panizzi completed a one-year internship at Chino Valley Equine in Chino, Calif., then stayed on for a fellowship until March 2006. During his time at Chino Valley, Panizzi gained exposure to a wide range of equine surgical procedures at the specialty surgical referral practice. outside of a horse’s intestine from becoming invaded with neutrophils, it’s less likely that we’ll get adhesions and other complications associated with these problems,” says Shoemaker, the study’s lead investigator. Specialists often use three other drugs when a horse undergoes colic surgery: flunixin meglumine, used as an anti-inflammatory agent and pain killer, and a combination of the broad-spectrum antibiotics gentamicin and penicillin. But because lidocaine is cheap, readily available at most surgical clinics and has minimal side effects, Shoemaker says the research team wanted to test its ability as a neutrophil-blocker. “If we can administer lidocaine and decrease inflammation, that’s the biggest benefit we’re hoping to achieve,” Shoemaker says. As outlined in the study, two surgical teams have conducted experimental surgery in 12 horses during the past 12 months. For each horse, the surgeons recreated two common scenarios related to small intestinal colic: partial occlusion (obstruction) of the small intestine and a distended bowel. Once the teams completed their surgical protocols in each horse, the patient received a saline solution intravenously (the control group) or an initial dose of lidocaine (1.3 milligrams per kilogram over five minutes) followed by a continuous flow of the drug at .05 mg per kg (per minute) over a two-hour period (the treatment group). To maintain the study’s impartiality, the surgical teams weren’t aware of which treatment was used on each horse. Dr. Andrew Allen, a veterinary pathologist at WCVM, is in charge of evaluating tissue samples from the horses’ intestines to measure the concentration of activated neutrophils and to evaluate the organ’s outer layer for neutrophil infiltration. By comparing results from horses in the treatment group to animals in the control group, the scientists can determine whether lidocaine administered intravenously has any impact on neutrophil numbers. And what if the lidocaine treatments appear to reduce neutrophil numbers and activity in the small intestine? “I think horse owners will respond very positively because everything we’re trying to do is prevent intestinal damage. If we can administer lidocaine and prevent any more intestinal damage, then horses with colic have a better chance of survival,” Shoemaker says. As a result, surgical specialists may soon have a new, cost-effective method of treating and preventing colic surgery complications, says Shoemaker. “Hopefully, lidocaine equals fewer complications, fewer repeat surgeries — and fewer horses dying.” H Jessica Eissfeldt is an award-winning equine journalist whose articles have appeared in Equus, Cablallus, Canadian Arabian Horse News, Riding Instructor and Blaze. The Saskatchewan-based writer holds a degree in English and news-editorial journalism from Oklahoma State University. PRECEDING PAGE: Drs. Ryan Shoemaker and Jenny Kelly with an equine patient at WCVM’s Veterinary Teaching Hospital. Photo: Juliane Deubner. Dr. Jenny Kelly, Resident By Jessica Eissfeldt Warm ocean breezes and ice and blowing snow seem an unlikely combination, but in Dr. Jenny Kelly’s case, they mesh perfectly for the time being. Originally from Hawaii and transplanted to Saskatchewan, Kelly grew up knowing she wanted to be a veterinarian: “I was always the kid who rescued baby birds that fell out of the nest, the one who brought home stray cats and dogs and cared for them.” That early interest in animals led to a zoology degree at the University of Hawaii. After completing her undergraduate work in 1995, Kelly taught high school for a few years before sending her application to Purdue University’s School of Veterinary Medicine in West Lafayette, Ind. Once she received her veterinary degree in 2002, Kelly began a one-year internship at the Surgicare Horse Center in Brandon, Fla. The experience was the ideal chance to work in her interest field — colic and post-operative colic complications — since her caseload at the equine referral clinic was mainly horses that developed sand colic. “At least one out of every five cases that I saw involved sand colic. There were ten times more colic cases in Florida than in Saskatchewan because of the sandy soil, the types of hay, and the way horses are housed.” says Kelly. After finishing her internship, Kelly stayed for another year to gain even more field experience with the clinic’s ambulatory emergency equine care group. In July 2004, she moved to Saskatoon, Sask., to begin a three-year large animal surgery residency and a Master of Veterinary Science program at the Western College of Veterinary Medicine. Based on her performance during the first year of her program, Kelly was selected as the 2005-2006 EHRF Research Fellow — a distinction that provides full financial support for her residency. This winter, the Fund’s advisory board and management committee recommended that Kelly’s fellowship be renewed for one more year. “I feel lucky and fortunate to be the EHRF Research Fellow. I think it’s also great that the Fund supports our project, and that we can experience so many aspects of research with the different researchers,” says Kelly. She and her residency supervisor, Dr. Ryan Shoemaker, are working on an EHRF-sponsored project that evaluates the use of lidocaine to prevent post-operative damage in colic patients. When Shoemaker brought the idea to Kelly, she saw it as a perfect fit. “The topic interested me because I had an understanding of colic overall, and I enjoy working with horses. It was just something that I wanted to look into: to help get a better prognosis for colic patients so owners can make more informed decisions about whether to go ahead with surgery.” At one point, scientists from the National Research Council contacted the WCVM researchers and came to the College to collect some of the study’s information about monitoring blood flow rates. “That’s what makes the study such a great tool because information is made available to so many people and will benefit so many others.” While Kelly has survived through a couple of Saskatchewan winters, she plans to return to warmer climes after she finishes her residency in 2007. Eventually, Kelly’s career plans may even take her back to her Hawaiian roots where once again, she could be a caregiver for the Island’s animals. Western College of Vet e r i n a r y Me d i c i n e 5 Based on statistics from large clinical studies, equine specialists can inform their clients about the percentage of horses that survive certain types of colic surgeries, the number of cases that develop post-operative complications and even the percentage of colic patients that suffer relapses. But can a clinician accurately predict the outcome for an individual sick horse? “Unless it’s something very striking, we can’t predict whether a particular horse is more likely to die or less likely to die,” says Dr. Katharina Lohmann, a specialist in veterinary internal medicine at the Western College of Veterinary Medicine (WCVM). “While we have a lot of information about colic patients overall, we’re not doing a good job of predicting the outcome for individual animals.” But things could soon change — mainly because researchers’ knowledge of equine genetics is growing. Some day, Lohmann says every horse’s clinical file may include a detailed “genetic profile” that clinicians could use to improve the diagnosis and treatment of individual animals. During the past 18 months, Lohmann has been one of the scientists working toward that long-term goal. The focus of her research, which is supported by WCVM’s Equine Health Research Fund, is an investigation of genetic risk factors for the development of endotoxemia — a life-threatening complication of many common equine diseases like colic, neonatal sepsis and endometritis. Specifically, the WCVM specialist is looking for the presence of single nucleotide polymorphisms (SNPs) in particular equine genes. As Lohmann explains, SNPs are stable genetic variations within populations that occur at a higher rate than random mutations. “About one per cent of a population will have SNPs, but so far, we don’t know enough about their occurrence in horses,” explains Lohmann. While other scientists have reported certain SNPs in some equine genes, “we still don’t know how frequently they occur, which ones are stable variations and which ones we can find repeatedly in horses.” To begin with, Lohmann is searching for SNPs in the promoter region of the tumour necrosis factor alpha (TNFa) gene — a gene that mediates the body’s inflammatory response. If one of the SNPs is found in parts of the TNFa gene that remain in the nucleus (known as the introns), these variations may have an effect on how much of the gene is translated or on the stability of the translations. “These variations in TNFa wouldn’t have an effect on what the protein looks like, but it may have an effect on how much of the protein is made. This could be important since the higher the number of inflammatory mediators produced, the more inflammation and more disease there is in the host’s body,” explains Lohmann. Scientists have already shown that SNPs in human TNFa are associated with an increased risk of death in human septic patients, she adds. “If you took the same amount of infection and put it into two people — one with SNPs and one without SNPs — the one with SNPs will have his immune response ‘turned on’ and is more likely to die because that person has a 6 H o r s e H e a l t h L i n e s • S u m m e r 2006 It’s In Your Genes Identifying genetic risk factors may eventually lead to the use of “genetic profiles” that would improve the way equine specialists diagnose and manage diseases such as neonatal sepsis and colic and the complications that arise from these conditions. predisposition to making a lot of TNFa. In other words, sepsis or endotoxemia is the original cause of the patient’s problems, but it’s the overabundance of inflammatory mediators (TNFa) that actually causes death.” Last summer, Lohmann and Sarah Stewart, an undergraduate summer research student, collected genetic material and blood samples from 50 healthy horses, then stimulated the horses’ blood samples with an endotoxin (E. coli) in test tubes. Next, the researchers used PCR (polymerase chain reaction) assays to amplify areas of interest in the genetic material for sequencing. Once sequencing is completed, Lohmann is evaluating the horses’ gene sequences for the presence of SNPs by comparing them with previously-published genetic sequences. While Lohmann has processed and evaluated all of the genetic material isolated from most of these samples, there’s still more work to be done before she can draw conclusions about the frequency of SNPs appearing in equine TNFa. Once all of her work is completed with the gene promoter, Lohmann also plans to reevaluate the horses’ genetic material for the presence of SNPs in endotoxin receptor genes (TLR4 and MD-2) — other key players in the body’s defense system against infection. “The beauty of this project is that it establishes the methodology we can use to genetically evaluate a variety of equine diseases,” says Lohmann, pointing to conditions like chronic obstructive pulmonary disease (heaves) as another potential research area. She also hopes her work will help to develop standardized, clinical definitions of equine diseases. A universally-accepted set of guidelines for diagnosis and treatment of diseases would then allow genetic researchers like Lohmann to collaborate with multiple veterinary institutions — a move that would substantially increase the number of clinical cases included in future studies. That collaborative spirit is already providing Lohmann enough clinical cases for her next EHRF-sponsored study where she will once again investigate the role of SNPs in the equine TNF gene promoter by comparing their frequency in septic and non-septic neonatal foals. The two-year project will involve approximately 100 foals admitted to veterinary teaching hospitals at WCVM and at the University of Georgia where Lohmann completed her PhD in 2004. “One benefit of working with septic foals is that our profession does have a ‘sepsis score’ which we can use to ensure that all of the septic foals involved in our study have similar levels of disease,” explains Lohmann. While her research of genetic risk factors is still in its early stages, Lohmann hopes the results of her studies will help to bring practitioners closer to the point where they can use an individual horse’s genetic information to make a more definitive diagnosis, to flag potential problems with specific drugs, and to be aware of a horse’s or a particular breed’s susceptibility to conditions like endotoxemia so they can be more proactive in using drugs or therapies to prevent further problems. “Genetic profiling won’t happen today or in the next few years, but it’s definitely something that could be in place 10 years from now,” says Lohmann, adding that there’s a more immediate benefit from her work. “All of this information is helping us gain a better understanding of these diseases. We’re learning more about how certain diseases develop and how they work, and that will eventually help us to improve the care we provide all of our equine patients,” says Lohmann. H Colic: Rolling vs. Operating Medical treatment of horses suffering from a type of colic called nephrosplenic entrapment of the large colon (NSELC) is just as effective and less expensive than surgery, reports a 10-year retrospective study conducted at the Western College of Veterinary Medicine (WCVM). The study, which was published in the Journal of the American Veterinary Medical Association, included 19 equine clinical cases at WCVM’s Veterinary Teaching Hospital between 1992 and 2002. Clinicians used medical options to treat 11 of the clinical cases while the remaining eight underwent surgery for this painful condition. Study authors Drs. Sameeh Abutarbush and Jonathan Naylor showed that both groups had similar mortality rates: two surgical cases died, while one horse died after medical treatment. However, the hospitalization period was three times longer for surgically-treated horses (an average of 8.6 days versus two days). As a result, their owners paid about five times more than the owners of horses that received medical treatment. “One reason for conducting this study was to demonstrate to practitioners that they can successfully use medical treatment out in the field for these cases as long as the diagnosis has been confirmed. If surgical treatment of NSELC is recommended but just isn’t an option and money is an issue for the client, why not try the medical treatment route?” says Abutarbush, who conducted the retrospective study during his large animal residency at WCVM. Commonly diagnosed in middle-aged horses, geldings and larger breeds, NSELC occurs when the colon becomes entrapped between the left kidney and spleen. Treatment choice depends on several factors including the clinicians’ preferences and the owners’ financial concerns. In three of the study’s medical cases, clinicians initially treated the horses with phenylephrine hydrochloride — a drug used to reduce the size of the spleen in an attempt to release the entrapped bowel. After the animals were trotted for 30 minutes, clinicians conducted transrectal and ultrasound examinations to confirm outcome. If horses fail to respond to drug therapy and the bowel or colon is still entrapped, the next step is to “roll” them, explains Abutarbush. The anesthetized horses are positioned on their right side, then rotated to lie on their backs while their abdomens are rocked back and forth for several minutes. In some cases, clinicians use a chain hoist to elevate the horses’ hindquarters before rocking their abdomens once again. The horses are rolled on to their left sides before clinicians repeat ultrasound and transrectal examinations. Surgical treatment is recommended in cases where a definitive diagnosis can’t be made, or when the patient shows severe signs of severe colic and systemic deterioration. Surgery is also recommended in mares more than five months pregnant or when the option of rolling doesn’t work, says Abutarbush. To ensure accuracy, Abutarbush and Naylor didn’t include cases where the colon was entrapped between the spleen and the left body wall in their study. “When the colon is between the spleen and body wall, these cases are very easy to treat: you just fast the horses, put them on intravenous fluid and they soon recover,” explains Abutarbush, now an assistant professor in the Atlantic Veterinary College’s Department of Health Management in Charlottetown, P.E.I. “Defining these colic cases as NSELC would provide incorrect numbers about treatment and outcome since these particular colic cases don’t need any further treatment. That’s why we were so stringent with our case selection: we wanted the results of our study to reflect the outcome of true cases of NSELC.” As well, the researchers only included cases in the medical treatment category if diagnosis and response to treatment was evaluated using both ultrasound and transrectal examinations. The combination of diagnostic methods ensured that all cases had accurate diagnoses and outcomes. Abutarbush SM, Naylor J. “Comparison of surgical versus medical treatment of nephrosplenic entrapment of the large colon in horses: 19 cases (19922002).” Journal of the American Veterinary Medical Association. 2005; 227(4): 603-605. The efforts of hundreds of Canadian horse enthusiasts — including one very talented quilt maker — are behind the Equine Foundation of Canada’s latest donation of $5,000 to the Western College of Veterinary Medicine. When Charlene Dalen visited WCVM’s Veterinary Teaching Hospital in December 2005, she soaked up as much information as she could about the hospital’s new arthroscopic fluid pump system. Her keen interest stemmed from the fact that she and hundreds of other horse enthusiasts across Canada spent several years raising $5,000 toward the purchase of the vital device through the Equine Foundation of Canada (EFC) — a charitable organization dedicated to the health and welfare of horses. “I knew our donors would have plenty of questions about this piece of equipment, so I wanted to learn as much as I could from the people who actually use it,” explains Dalen, EFC’s representative in Saskatchewan. Dalen’s information sources were Drs. David Wilson and Ryan Shoemaker — two of the hospital’s equine surgical specialists who rely on the fluid pump system while they’re using arthroscopy to diagnose and treat joint-associated lamenesses in horses. Some examples of common arthroscopic procedures Horse Health One Step (Stitch) at a Time include the treatment of articular (joint) “chip” fractures and the removal of osteochondritis dissecans (OCD) lesions in horses’ stifle or hock joints. With the help of video images, the specialists described how the fluid pump system uses pressure to maintain a steady flow of fluid through a horse’s joint during arthroscopic procedures so there’s no build up of excess blood and debris. “It keeps the joint distention at just the right level so we don’t suddenly run into the problem of not being able to see during a procedure or having fluid accumulate around the joint due to excessive pressure,” Shoemaker explains. Wilson adds that the system maintains a fluid pressure at a high enough level to prevent hemorrhaging into the joint during a surgical procedure. “If hemorrhaging isn’t prevented, then the fluid gets too bloody and makes it difficult for us to see,” says Wilson. Another use for the unit is laparoscopic “irrigation” when specialists need to rapidly infuse fluids during a procedure. For Dalen, the chance to learn more about the equipment, to meet the specialists and to hear the genuine appreciation in their voices made her visit to the College extremely worthwhile. “I was totally impressed after hearing about their work,” says Dalen. “Through our gift, we’re helping these specialists do a more efficient and a more accurate job of helping horses in trouble. That’s something all of us who helped to raise this money should be really proud of.” Equally impressive are the fund raising efforts of the people who contribute to EFC — members of all types of breed organizations and sport groups. In the past three decades, these dedicated supporters have raised more than $150,000 by organizing trail rides, raffles and other fund raising events in every Canadian province. While EFC previously directed some of these funds to scholarships and research grants, the foundation now focuses its efforts on purchasing medical equipment that’s used to diagnose and treat horses. To meet this goal, EFC rotates its annual donation among Canada’s four regional veterinary colleges. Altogether, EFC has contributed $31,190 to WCVM for equipment purchases and research grants, plus it has provided $20,000 worth of scholarships for the College’s veterinary students. “The foundation raises money all across Canada, but when a province knows that that next contribution will go to its regional veterinary college, local horse people usually go above and beyond to raise funds since the C O N S T R U C T I O N Z O N E This spring, crews have made rapid progress on WCVM’s expansion — a series of projects that will deliver more specialized services, new technologies and a higher level of health care to large and small animals. For WCVM’s large animal clients, the upgrades will bring big benefits like a safer chute complex in the large animal handling area, an expanded “stocks” area for equine patients, and more spacious suites for large animal surgery, Other improvements include better biosecurity, larger isolation facilities for horses, and the introduction of nuclear scintigraphy to the College’s medical imaging repertoire. At top right, workers prepare to pump concrete into the Veterinary Teaching Hospital’s column and elevator shaft forms. Bottom right: the two-storey research wing is taking shape on the College’s south side. For further construction updates, visit www.wcvm.com. Make a donation to the Veterinary Teaching Hospital Expansion Campaign by: •using the enclosed tear out card • visiting www.wcvm.com/supportus • contacting Joanne Wurmlinger, WCVM development officer, at 306-966-7450 (joanne.wurmlinger@usask.ca). donation will stay within their region and benefit their communities,” says Dalen. In Saskatchewan, that extra effort translated into a raffle for a beautiful quilt made by CMHA member Peggy Gwillim of Strasbourg, Sask. Gwillim’s horse-themed handiwork helped to raise $1,000 — an exceptional contribution to the foundation’s annual donation. “It’s not just money that makes this organization so successful: it’s all of the time and effort that people put into making quilts, organizing fund raisers and praying for good weather during our trail rides and poker rallies,” says Dalen with a laugh. “We just couldn’t accomplish as much as we do without all of these people who are willing to go that extra mile for their horses.” One of the most dedicated supporters of the foundation was George Wade of Nova Scotia, who founded the organization in 1978. Wade died in 1997 — but his dream of contributing to the health of all horses continues to grow in the hands of his friend, Eldon Bienert of Leduc, Alta. “Eldon worked very closely with George to set up the foundation, and as EFC’s president, Eldon does a wonderful job of communicating George’s vision to the next generations of horse owners,” says Dalen, adding that the foundation has been successful in involving young horse people in fund raising events. “People are willing to give to the Foundation and to support its work because they really do love their horses — it’s that simple.” H F o u n datio n F acts • George Wade, a Morgan horse breeder from Coldbrook, N.S., founded the Equine Foundation of Canada in 1978 to improve the health and welfare of Canada’s horses. • Initially christened the Canadian Morgan Horse Foundation, the charity’s name was changed to Equine Foundation of Canada to reflect its aim of helping horses of all breeds and disciplines in all Canadian provinces. While EFC is an affiliate organization of the Canadian Morgan Horse Association, it has its own president and board of directors. •EFC has contributed $89,650 to the purchase of equipment and equine health research in Canadian veterinary colleges. An additional $64,000 has supported regional scholarships, while another $2,300 has supported other horse health associated activities in Canada. Altogether, EFC has invested $155,950 in horse health care, research and training. PRECEDING PAGE (from left to right): Charlene Dalen, Dr. David Wilson and Dr. Ryan Shoemaker with the new fluid pump system (foreground). Western College of Vet e r i n a r y Me d i c i n e 9 E q u i n e E d , Electronic-style Through Dr. Jonathan Naylor’s explorations of new media, future equine specialists at WCVM are now using tools like multimedia teaching modules, electronic stethoscopes, and digitalized sound and images to learn more about the horse. Taking notes during a lecturer’s PowerPoint presentation, downloading electronic copies of journal articles and working through a multimedia teaching module is now routine for students at the Western College of Veterinary Medicine (WCVM). That’s a far cry from the 1970s when Dr. Jonathan Naylor was a veterinary student at the University of Bristol. Back then, he and his classmates relied on their notes and journal readings to learn, while their professors simply transferred information through lectures with little discussion or direction about the look and feel of a sick patient. Naylor used that same basic model during the early days of his teaching career — until he discovered computers. “Computers revolutionized my life: my research, writing, managing databases and references. That’s when I thought about how it could affect teaching,” says Naylor, a specialist in veterinary internal medicine who joined WCVM’s faculty in 1981. Naylor initially used simulation software to develop exercises that gave students experience in diagnosing and treating different types of cases. He saw them as a step between the gaining of knowledge and its application to clinical material — with the advantage that the modules could be used at the student’s convenience. Mistakes, while penalized by the program, didn’t affect patient care so the student could explore different diagnostic and treatment options. His next project: using technology to interpret equine heart sounds. “The horse has a wonderful heart which I never quite understood as a student or as a young veterinarian,” says Naylor. “But with new technology, it’s easy to understand: it has a nice, slow heart rate that’s well-defined with lots of interesting murmurs and arrhythmias. There’s a lot of interest in the equine heart for insurance purposes, so it was a good place to start. New media make it possible to transfer our new understanding in ways that are clinically relevant.” When Naylor spent a sabbatical leave at the University of Edinburgh several years ago, he worked with a cardiologist, Dr. Karen Blissitt, and a wonderful machinist, Jimmy Brown, to develop an electronic stethoscope that recorded horses’ heart sounds. Then he perfected the design of software that could display those heart sounds on computer together with their interpretation. The last piece of the puzzle was to combine the sounds and computerized indicators with ultrasound images of the beating heart taken on live horses. “When we heard a murmur, we could actually see the murmur happening in the horse’s heart with ultrasound images,” explains Naylor. “If it hadn’t been for ultrasonography, we would still be trying to understand what those sounds meant.” 10 H o r s e H e a l t h L i n e s • S u m m e r 2006 The result was Hearing Horse Hearts: An Illustrated Guide to Equine Cardiac Auscultation — an educational CD that integrates digital audio and video clips with still images and text. Since its release in 2002, Naylor believes the CD has helped to increase veterinary students’ understanding of horses’ heart sounds and to standardize their descriptions of what they hear. The veterinary scientist also used his resources to record and interpret horses’ gastrointestinal sounds. These findings, combined with his equine cardiac auscultation work, will ultimately be available on one updated CD. “What I’d eventually like to develop is a complete, audiovisual guide to equine internal medicine,” says Naylor, who developed a similar CD for bovine practitioners. Another of Naylor’s multimedia projects is a CD that walks students through the process of stomach tubing a horse. The program includes self-learning modules, synchronized video clips, interactive tutorials and a literature review. The CD was also the focus of a study to determine whether students preferred live stomach tubing demonstrations or learning about the process through the multimedia program: most of the study’s participants preferred the latter. “We’re gaining support from the profession and industry for these projects because they can potentially replace teaching animals with simulated exercises on CD. They also improve students’ skills when they actually use these techniques in practice,” says Naylor. He adds that increased use of technology out in the field and knowledge-thirsty horse owners are two other factors influencing the acceptance of high-tech tools. “Access to knowledge is becoming easier, but techniques to apply that knowledge — that remains valuable,” points out Naylor. “I don’t think veterinarians need to be concerned that technology will replace them. However, our best protection is to adapt and use the technologies so we’re ready for the next step.” What about future equine veterinarians? How will their education differ from the education that Naylor and his classmates received three decades ago? “They will definitely leave veterinary school with better skills,” says Naylor. “Electronic learning improves their interpretive and manipulative skills, and gives them far more opportunities for ‘active learning.’” As for the basic “information transfer” approach to teaching, Naylor believes the days when professors recited facts in front of a lecture theatre are past. “That’s a strength of new media. It encourages more involvement in the learning process, and that will only help to improve the quality of our students’ education.” H Q How has WCVM’s Equine Club contributed to your training? It’s been a huge help. Club members usually organize “wet labs” so students gain hands-on experience with teeth floating, plaster casting, joint injections and administering drugs. The club’s links with the American Association of Equine Practitioners (AAEP) keep us aware of any awards, plus groups can arrange to attend the AAEP’s annual convention or meetings of the Western Canadian Association of Equine Practitioners. The Equine Club also organizes seminars for local 4-H and Pony Clubs, and it’s a great way to review all that we’ve learned. Q What other activities have contributed to your education? I attended equine-oriented lectures and volunteered at events like local endurance rides. During the summer after my second year, I worked for an equine veterinarian who had many clients at Assiniboia Downs in Winnipeg, Man., so it was a fantastic experience. Last summer, I worked in a mixed animal practice in rural Manitoba —the same practice where I used to volunteer. Q What happens in your fourth and final year at WCVM? Besides our required four-week rotations, we can choose rotations related to our interests. In May 2005, I spent four weeks with WCVM’s equine surgery and field service, and another four weeks with surgery and field service last fall. This spring, I took rotations in large animal medicine and reproduction. We can also spend a rotation at an external university or practice of our choice that offers additional experiences for our education. Last August, I spent time in California at the Alamo Pintado Equine Referral Center where equine specialists use magnetic resonance imaging, computed tomography and nuclear scintigraphy. The clinic’s mentor for interns and externs took us on rounds and discussed different procedures that specialists were performing on the clinic’s patients. The Making of an Q Equine Veterinarian Born and raised on a cattle and sheep farm near Boissevain, Man., Tracy Epp rode her first horse at two, joined her local 4-H Club when she was eight and decided to become a veterinarian when she was 12. This spring, nearly a dozen years after making her career choice, the 23year-old student earned her Doctor of Veterinary Medicine (DVM) degree at WCVM. Her training has prepared her to work with a range of large and small animals in a variety of areas — but after reviewing her options, Epp wants to focus on horses. “I always thought I would like to be in a mixed animal practice, but as I’ve learned about different aspects of veterinary medicine, it’s the equine aspects of the profession that spark my interest,” says Epp. “I don’t think that would have been the case if I hadn’t grown up with horses and started riding them at an early age.” Q How much exposure did you have to veterinarians when you were younger? We had veterinarians come to our farm, but what really helped me was when the local veterinary practice allowed me to volunteer while I was in high school. I watched surgeries, did odd jobs and asked tons of questions about beneficial classes and types of experiences. What are your future plans? In June, I begin a year-long internship at the Alama Pintado Equine Referral Center where I’ll have exposure to advanced imaging, surgery, neonatal care and more. I still want to learn about all aspects of equine-related veterinary medicine, but I may eventually apply for a residency program in a specialized area. Q You love animals, but what ultimately attracts you to veterinary medicine? This profession isn’t just about working as a veterinarian in a mixed animal practice: you can work for the government, conduct research or become a specialist in surgery, radiology or internal medicine. It’s a fast-changing area where new drugs, better ways to manage patients and new surgical techniques are being introduced every year. You can continuously learn and grow, and you can customize your role in veterinary medicine to whatever you want. For me, that means I can work with horses — and that freedom is what I really love about this profession. H For more information about WCVM’s veterinary degree program, visit www.wcvm.com. Western College of Vet e r i n a r y Me d i c i n e 1 1 What sets Clinical Anatomy of the Horse apart is that this is the only atlas of equine anatomy composed of photographs of rapidly dissected, fresh tissue. Those dissections are complemented by numerous images made by radiographs, computed tomography, ultrasonography and endoscopy. “We wanted to illustrate what normality really looks like. When you examine a diseased organ in pathology, you don’t only want to know about its shape, you want to know about its colour and texture. This book is intended to portray some of those subtleties,” explains Flood, who describes the atlas as an “illuminating companion” to the standard veterinary anatomy texts. Flood, now professor emeritus at the Western College of Veterinary Medicine (WCVM), is an anatomist and reproductive biologist. Clayton taught anatomy at WCVM for some 15 years and now specializes in equine locomotion and gait analysis at Michigan State University’s College of Veterinary Medicine. Rosenstein is an associate professor specializing in medical imaging at MSU. This isn’t the first time that Flood and Clayton have collaborated on a book. In 1996, the two long-time friends shared the work of producing the Color Atlas of Large Animal Applied Anatomy — a pictorial guide to the anatomy of the horse, cow, sheep, llama and pig. “Hilary focused on the head and limbs while I did the trunk: thorax, heart, digestive tract and reproductive tract,” explains Flood. The popular atlas, which was eventually translated into Portuguese, is now out of print. But based on its success, the publishers approached Clayton and Flood about producing a similar style of book that focused on equine anatomy. While the pair decided to split the anatomical areas as they had done in their previous project, they also asked Rosenstein to contribute additional medical images to the text. For Flood, finding high quality images to illustrate anatomical parts of the horse’s trunk soon became an interesting challenge. Since he had relied on dissections of cattle, sheep and other large animals to illustrate some of the basic anatomical structures in the previous atlas, he couldn’t reuse many of the illustrations. Another complication was that publishers had lost the original image files used in the earlier project. Undaunted, Flood gathered more images from a variety of sources to illustrate his designated areas of the atlas. Drs. Gregg Adams and David Wilson at WCVM supplied some of the photographs, while University of Saskatchewan photographer David Mandeville was responsible for a large number of the dissection images that appear in the atlas. As well, many of the photographs The True View of Equine Anatomy If you’re interested in studying the anatomy of the horse in vivid detail, leafing through the 122 pages of Clinical Anatomy of the Horse by Drs. Hilary Clayton, Peter Flood and Diana Rosenstein is the closest to seeing and experiencing the real thing in an anatomy lab. Together, the three authors have created a unique resource for students, clinicians and pathologists as well as for people who work with horses on a daily basis. were found in Flood’s 40-year compilation of images — including some that he recently took using a digital camera. “To some extent, this collection extends over my entire teaching career,” says Flood, flipping through the pages of the atlas. “It goes from Kodachrome in the 1960s and 1970s to the joys of digital imagery today.” The project also expanded Flood’s ability to use imaging editing software on his computer. Through the magic of Photoshop, he meticulously removed bits of dirt and hair, enhanced details in the medical images, and even “melded” images together. “It’s like all of such projects: afterwards, if you can’t think of ways you could have done better, you might as well be dead,” says Flood. “But I’m fairly pleased with it.” Based on the initial response, Clinical Anatomy of the Horse is meeting the public’s demand for a highly realistic portrayal of equine anatomy. Nearly 1,500 copies have been shipped to customers in North America and Europe since the book became available in November 2005, and Mosby Ltd. (the publisher of the atlas) has now scheduled a second printing for this year. H Visit www.us.elsevierhealth.com for more details about Clinical Anatomy of the Horse. PRECEDING PAGE: Dr. Peter Flood, professor emeritus at WCVM. DR. HILARY CLAYTON: Equine Motion Detector When Dr. Hilary Clayton came to the Western College of Veterinary Medicine as one of its D.L.T. Smith visiting scientists last spring, it was a homecoming of sorts for the internationally-known equine scientist. Clayton, who has held the McPhail Dressage Chair in Equine Sports Medicine at Michigan State University’s College of Veterinary Medicine for the past nine years, was an anatomy professor at WCVM from 1982 to 1997. It was during her 15-year stay in Saskatoon, Sask., that Clayton’s research interests in sport horse conditioning, equine locomotion and equine biomechanics gained real momentum. Those early research initiatives — some of which received financial support from the College’s Equine Health Research Fund — earned recognition from the international community of equine scientists as well as the sport horse world. During Clayton’s time at WCVM, some of her many achievements included writing a book on conditioning sport horses in 1991, co-authoring the Colour Atlas of Large Animal Applied Anatomy with her WCVM colleague Dr. Peter Flood, and being part of the chief research group for dressage and show jumping at the 1992 Summer Olympics in Barcelona, Spain. As well, Clayton was actively involved in EHRF — serving as editor of Horse Health Lines and as chair of the Fund’s management committee for a number of years. Today, Clayton is considered the world’s leading researcher in equine locomotion and biomechanics. Besides publishing a number of peer-reviewed journal articles, book chapters and conference proceedings, Clayton has shared her research findings at international conferences, meetings and events for equine veterinarians, members of the sport horse community and horse enthusiasts. She is also the author of Conditioning Sport Horses, Equine Locomotion and The Dynamic Horse, and co-author of her latest book — Clinical Anatomy of the Horse. To learn more about Clayton’s work, visit the McPhail Equine Performance Center’s website: http://cvm.msu.edu/dressage Q. How do you choose your projects? When I went to Michigan State University, Mary Anne and Walter McPhail had no specific requirements for research — they simply gave the money with the idea of creating a research centre to study performance and lameness of sport horses. Mrs. McPhail has been a dressage enthusiast all of her life, so many of our projects are of great interest to her. Our current projects include cutting edge research that involves sophisticated equipment and custom software that we have developed for equine applications. In addition, we have projects that are of direct relevance to veterinarians and trainers. I spend a lot of time conveying the results to riders, trainers and judges because that was a big part of the McPhails’ vision. They wanted practical research that could produce tangible improvements in the equestrian sports. Q. How has your dressage training influenced your research? Would you ask the same questions if you weren’t a serious rider? No, I don’t think I would be interested in the same types of questions if I didn’t ride. I like to study things that are important to riders and trainers. I started doing this type of research at WCVM and have continued it at Michigan State University. Western College of Vet e r i n a r y Me d i c i n e 1 3 Q. What interested you in questions involving bits and bitting, rein tension and rider motion? I’ve worked on these research projects mainly because I was just curious about some of those questions. For example, it has been suggested that horses are unable to swallow with a bit in their mouth, so I designed a study to measure frequency of swallowing during exercise while wearing different bits and bridles. For that study, we put an endoscope in the horses’ throats to record swallowing as they cantered on a treadmill. We tested a bitless bridle as well as different bits, and found minimal differences in swallowing frequency. However, we did find that swallowing frequency with different types of tack varied a great deal between horses, regardless of the bit and bridle used. Q. What’s a “gait fingerprint”? How will this technology help to develop this concept? A “gait fingerprint” is the idea of a horse having a characteristic gait profile that doesn’t change significantly with growth and aging. It’s based on work that was done by Dutch scientists who studied young foals over a period of two years. The group showed that the horses’ swing duration, their protractionretraction angles and the joint angular events are consistent from the foal stage to adulthood. This allows the possibility of assessing the movement of a performance horse at a young age. Q. Can you tell us about your horses? Most of the horses I owned in the past were Thoroughbreds or Warmbloods, but now I own Arabians that were bred at MSU’s Horse Teaching and Research Farm. My first Arabian was MSU Magic J, named after Magic Johnson (an MSU graduate). I’ve taken him to the Arabian Nationals three times and we’ve come with a championship each time. I have another Arab that I bought at our university’s annual auction. We have a program where students “break” and train young horses, then sell them at auction to support the horse breeding program. The farm manager always keeps her eyes open for potential dressage horses, and she called me about this one. When I went to see him, he was so small — but he was a lovely mover with three really good gaits. At the sale, he was so scared when he came in the ring! I bid on him intending just to get the bidding started, but no one else placed a bid so I went home with another horse! MSU Fanfare has proved to be a great buy. Last year, as a five-year-old, he won two dressage championships at the Arabian Sport Horse Nationals. Q. What hot topics in dressage are you investigating? One of the hot topics is the difference between “competitive” versus “classical” dressage. An example of how my research was involved in this debate was when I analysed the “piaffe” in videos from the Olympics. According to the dressage rules, piaffe was supposed to have a prolonged period of “suspension.” The biomechanical definition of suspension is a period when all four feet are off the ground. My research showed that there was no suspension in piaffe; when one pair of diagonal feet were on the ground, the other diagonal feet were held momentarily in an elevated or “suspended” position, but at no point were all four feet off the ground. The question then arose as to whether this was an aberration of competitive dressage and that if I looked at classically trained horses the results would be different. So I videotaped some of the classically trained Lippizzaner horses at the Spanish Riding School in Vienna, Austria, and found that they did not show suspension either. 14 H o r s e H e a l t h L i n e s • S u m m e r 2006 Q. Will the day will come when lameness analysis technology replaces the traditional lameness exam? No, I think the lameness exam will always be a mainstay. Our goal in gait analysis is to determine what are the most useful features of gait for experienced veterinarians to focus on when they examine a horse for lameness. It’s a matter of taking all of the small nuances that they pick up and send to their “computer” brain, then trying to find a computerized representation that will sort out all of that information. Biomechanical analysis is very useful for increasing our understanding of how and why horses go lame and for monitoring progress over time. Q. Why is equine locomotion analysis still relatively new? The limits of technology held us back in the 1990s, but there have been huge changes during the past 10 years. We can do so many things so much faster and more accurately now — and that’s why this is such an exciting area for research right now. Q. You work with the same type of virtual animation used in “Lord of the Rings” and “Polar Express.” How has this technology affected your work? It allows us to analyse the whole horse at once rather than only looking at one limb or one side of the horse’s body, and it provides results much more quickly than the older systems for gait analysis. We can slow down the motion to detect subtle changes that we wouldn’t be able to see in regular movement. We also use the data to calculate other biomechanical data that we can’t measure directly. We are applying this information to develop a computerized “lameness model” to teach undergraduate and graduate students about different types of lameness. H PRECEDING PAGE: Dr. Hilary Clayton and MSU Magic J perform a walk pirouette at a dressage competition in Virginia. ABOVE: During a study of rider technique, Clayton and her research mount, Raison, wear markers (the glowing balls) that are detected by infrared cameras. Clayton is also wearing EMG (electromyographic) electrodes that detect activity in specific muscles. As well, rein sensors measure tension in the scientist’s reins. Program Brings Honours and Better Health to Horses Nearly two years ago, one of Dr. David Paton’s clients was faced with a tough decision: the farmer’s favourite Clydesdale horse was so ill that the only humane choice was to euthanize the prized animal. “It was quite an emotional situation for him because he was very close to this horse. He was a typical farmer who didn’t want to show his feelings, but I knew it was very hard for him,” recalls Paton, a veterinarian in Aldergrove, B.C. He and Dr. Eric Martin operate Paton & Martin Veterinary Services Ltd. — an equine clinic that serves horse owners in B.C.’s Lower Fraser Valley. Paton had often sent sympathy cards and flowers to grieving clients in the past — but in this case, those gestures just didn’t seem right. That’s when Paton thought of the Equine Health Research Fund. Dedicated to supporting equine health research and training programs at the Western College of Veterinary Medicine (WCVM), the Fund has helped to improve the quality of horse health care for horses of all breeds and ages throughout Western Canada. Paton, who is a member of the Fund’s advisory board, was convinced that it was an ideal fit and made a donation to EHRF on the farmer’s behalf. “My client phoned me up when he received my note, and he was very grateful. For him, that was a fitting tribute for his horse,” says Paton, who has repeated the gesture for other clients. “I’ve had several people actually write thank you letters rather than calling or mentioning it the next time we see them. In particular, I remember the response of one client — a young woman — who had owned her horse for a long period of time before it died of cancer. She was very appreciative of our donation, and it was a great comfort for her to know that a contribution in her horse’s memory was going to benefit the health of other horses.” Based on those experiences, Paton began to wonder: if this was a fitting way to honour horses at his practice, what if other veterinary clinics across Western Canada made the same gesture? In February 2005, Paton introduced the idea of developing an equine memorial program at the EHRF annual meeting. His fellow board members responded with enthusiasm, and almost a year later, Paton described aspects of the initiative at the Western Canadian Association of Equine Practitioners’ annual meeting in Saskatoon, Sask. Every time a veterinarian makes a memorial donation of $10 or more to the Fund in honour of a deceased patient or client, administrative staff at WCVM’s Research and Development Office sends the client or the client’s family a letter acknowledging the veterinarian’s contribution to EHRF. The College also includes some background information about the Fund and about its research and training activities. “It gives you a warmer, more rewarding feeling to contribute money to something that has long-term benefits for equine research. Flowers are beautiful, but they’re not going to last as long as a donation to the horse health fund,” points out Paton. He adds that practitioners and horse owners alike shouldn’t feel that only large investments of thousands of dollars make any difference in horse health research. “That’s just not true: a little bit of money goes a long way in certain areas of research, and the College is well-suited to conducting some effective research without having to secure huge amounts of money per project. All of those donations — $25 here, $25 there — they all add up to do so much.” Paton initially donated to the Fund only on behalf of long-time clients, but his practice now sends in memorial donations for any client who loses a horse. The practitioner says the program is also ideal for honouring the lives of people and can serve as a fitting tribute to individuals who have enjoyed a lifelong involvement with horses. “It shows that you care and that you’re sorry for the family’s loss. At the same time, it will hopefully help to give the Fund greater exposure and more potential for raising more money for research. In the long run, that will benefit everyone who is involved in horses,” says Paton. H For more information on how to donate to the Equine Health Fund, visit www.ehrf.usask.ca, call 306-966-7453 or send an email message to wcvm.research@usask.ca. Western College of Vet e r i n a r y Me d i c i n e 1 5 G A L L O P I N G G A Z E T T E Changing faces in equine health: Dr. Jonathan Naylor, a 24-year member of WCVM’s Department of Large Animal Clinical Sciences, left the College last fall to take on a new position at Ross University’s School of Veterinary Medicine on the West Indies island of St. Kitts. Naylor’s numerous research contributions to equine health include the initial identification of HYPP (hyperkalemic periodic paralysis) in Quarter horses, the discovery of the true function of equine guttural pouches, using new technology to interpret equine heart and gastro-intestinal sounds, and developing new electronic teaching tools to enhance veterinary training. Naylor regularly shared his research findings with veterinarians and western Canadian horse owners, and he was an active member of the Equine Health Research Fund’s management committee. A former editor of Horse Health Lines, Naylor also fulfilled the editorial role for a highly successful continuing education publication called Large Animal Veterinary Rounds for five years. • A new WCVM faculty member is Dr. Fernando Marqués who graduated from the University of Buenos Aires in 1987. For more than 15 years, Marqués practised equine medicine in Argentina — primarily in the areas of theriogenology, neonatology and sports medicine on Thoroughbred stud farms and equine facilities. Marqués became a diplomate of the American College of Veterinary Internal Medicine (ACVIM) in 2005 after successfully completing a large animal internal medicine residency at the University of Wisconsin-Madison. His research interests include infectious diseases, sepsis and inflammation, the immune response to infection, and vaccine formulation. Besides his clinical and research interest in horses, Marqués has competed in show jumping as a second category rider (first category being professional) under the Argentinian Equestrian Federation for many years. As well, Marqués is a long-time show jumping instructor and a successful coach whose riding teams have won multiple championship awards. student ATTENDS symposium: WCVM graduate student Dr. Tal Raz will be a presenter at the Ninth International Symposium on Equine Reproduction in The Netherlands this summer. The symposium, which takes place from Aug. 7 to 11 in the southern Dutch town of Kerkrade, will include 150 oral and poster presentations by researchers from around the world. Raz, a Master of Science student and theriogenology resident under Dr. Claire Card’s supervision, will present two research abstracts based on research conducted at WCVM. The first presentation is on “the effects of equine arteritis virus positive semen on mare fertility” while the second abstract focuses on “the effect of equine follicle stimulating hormone (eFSH) on pregnancy rate and embryo development in mares.” These presentations will be published along with all of the conference’s proceedings as extended abstracts in a special issue of Animal Reproduction Science. Vi s i t H o r s e H e alth Lines on line at www.ehr f.usask.ca PUBLICATIONS MAIL AGREEMENT NO. 40112792 RETURN UNDELIVERABLE CANADIAN ADDRESSES TO: Research Office, WCVM University of Saskatchewan 52 Campus Drive Saskatoon, SK S7N 5B4 wcvm.research@usask.ca HORSE HEALTH IN TRANSIT: As the Royal Canadian Mounted Police Musical Ride makes its annual pilgrimage across North America, the Ride’s team members take great pains to ensure the health and safety of their 36 horses. Before the Warmblood horses leave in May for their six-month tour, the Musical Ride’s regular veterinarian thoroughly examines each animal and ensures that all of their vaccinations and medical records are up to date. On the road, Ride team members rely on on-call veterinarians in every region to provide medical assistance. During their travels, the horses’ mobile homes are padded, rubber-matted stalls in tractor-trailer trucks. The fleet’s professional drivers stop every five or six hours so officers can water the horses and check for any signs of trouble. Once the Musical Ride arrives at a community, local organizers deliver feed for the horses. “They need to supply about 500 pounds of oats and 1,000 pounds of hay per day. Since water quality varies across the country, that can make things challenging on the road — especially in hot weather — and we have to monitor each horse’s water intake during the day,” explains equitation instructor Corporal Eric Simard. Two officers are always on stable duty, 24 hours a day, to ensure that each horse is eating and drinking properly. Some centres need to be creative in supplying shelter for the Ride’s horses. “Organizers have set up stalls in tents or in large portable shelters. We’ve even had box stalls in the middle of a forest!” says Simard. But the best makeshift stable is a typical Canadian solution: local hockey rinks, says Simard. “The aeration is great, the building is large, and we can keep our eye on all of the horses at the same time. It’s perfect.” • Visit www.ehrf.usask.ca to read more about the Ride’s horse health care plans, or visit http://www.rcmp-grc.ca/muscialride/index_ e.htm to view the Ride’s 2006 schedule.