I. ASCRC General Education Form (revised 9/15/09) Use to propose new general education courses (except writing courses), to change existing gen ed courses and to remove designations for existing gen ed courses. Note: One-time-only general education designation may be requested for experimental courses (X91-previously X95), granted only for the semester taught. A NEW request must be submitted for the course to receive subsequent general education status. Group III. Language VII: Social Sciences (submit III Exception: Symbolic Systems * VIII: Ethics & Human Values separate forms IV: Expressive Arts IX: American & European if requesting V: Literary & Artistic Studies X: Indigenous & Global more than one VI: Historical & Cultural Studies XI: Natural Sciences general w/ lab w/out lab X education group *Courses proposed for this designation must be standing requirements of designation) majors that qualify for exceptions to the modern and classical language requirement Dept/Program Biological Sciences Course # BIOL 191N Course Title Prerequisite Human Genetics, Your Family, and Global Health Credits II. Endorsement/Approvals Complete the form and obtain signatures before submitting to Faculty Senate Office Please type / print name Signature Instructor Phone / Email 3 Date 9/21/12 Sarah Certel x6479 sarah.certel@umontana.edu Program Chair Charlie Janson Dean Chris Comer III. Type of request New X One-time Only Change Remove Reason for Gen Ed inclusion, change or deletion Description of change IV. Description and purpose of new general education course: General Education courses must be introductory and foundational within the offering department or within the General Education Group. They must emphasize breadth, context, and connectedness; and relate course content to students’ future lives: See Preamble: http://umt.edu/facultysenate/archives/minutes/gened/GE_preamble.aspx See attached Course Description V. Criteria: Briefly explain how this course meets the criteria for the group. See: http://umt.edu/facultysenate/documents/forms/GE_Criteria5-1-08.aspx This course will use learning activities to formulate hypotheses, understand and test the hypotheses through case studies and class discussions, and present the results. Students will learn how the science of human genetics is used to draw conclusions on the risk of genetic disease. Students will learn how molecular biological technology is used to rigorously test aspects of genetic risk. VI. Student Learning Goals: Briefly explain how this course will meet the applicable learning goals. See: http://umt.edu/facultysenate/documents/forms/GE_Criteria5-1-08.aspx Students will learn the general principles associated with human genetics. Students will understand the methods used in genetic testing. Students will learn how to accurately interpret and verify genetic testing results. Students will acquire an appreciation for country- and culture-specific differences in attitudes toward implementation and use of genetic information. VII. Justification: Normally, general education courses will not carry pre-requisites, will carry at least 3 credits, and will be numbered at the 100-200 level. If the course has more than one pre-requisite, carries fewer than three credits, or is upper division (numbered above the 200 level), provide rationale for exception(s). VIII. Syllabus: Paste syllabus below or attach and send digital copy with form. The syllabus should clearly describe how the above criteria are satisfied. For assistance on syllabus preparation see: http://teaching.berkeley.edu/bgd/syllabus.html (attached) See attached Course Description (with syllabus) Please note: Approved general education changes will take effect next fall. General education instructors will be expected to provide sample assessment items and corresponding responses to the Assessment Advisory Committee. Human Genetics, Your Family, and Society 3 credits Instructor: Fall 2013 Dr. Sarah Certel Skaggs 393 (406)-243-6479 sarah.certel@mso.umt.edu Office Hours: T (3:30-5), F (10-11) Lectures: TTH, 2:10-3:30 Location: Skaggs Building 174B Textbooks: Human Genetics: Concepts and Applications by Lewis, 10th Edition. Web Page: Course Description: This course will address two fundamental biological and societal questions; how do genes direct and/or influence our health, and how do cultural, climate, ethical, and political issues affect the testing for genetic diseases? In covering the first unit, the material will give students a practical knowledge of the principles of human genetics, which will serve as a foundation to understand inherited diseases, the application of family information, and diagnostic methodologies. The course will cover the basics of heredity; what is a gene, what is a chromosome, what is genetic material. We will move on to understanding the patterns of inheritance of genes, including those associated with genetic diseases such as cancer and Alzheimer’s disease, and the sequence and content of the human genome. We will also address how genes function and how individual gene variation affects health risks and the interpretation of genetic tests. A key goal is to empower students to make informed choices about their behavior and treatment with respect to genetic diagnoses they may receive about themselves or family members. In the second unit, students will learn how the physical, cultural, and political environment impacts the diagnosis of genetic diseases. Topics will include how contact with pesticides in agriculture-focused states such as Iowa or Nebraska or contact with disease-carrying mosquitoes in South-East Asia may changes the risk of developing disease in populations with existing genetic predisposition. In addition, the course will cover how the direct and indirect effects of global climate may change the risk of developing different diseases such as cancer in specific populations. We will address the ethical issues surrounding the cost of genetic testing – who should pay for such information and does society benefit from the treatment or the prevention of genetic disease, for example. Students will learn how cultural and religious issues affect the logistical implementation of treatment. For example, how do different cultures treat depression, which has a strong genetic component, how much does the different treatments cost, and is one more effective than another? Finally, we will discuss how governmental policies affect the treatment of genetic disease. This course will: Provide sufficient background to understand the biology of genes and genetic issues as they relate to family inheritance, genetic test results, and various disease conditions such as cancer. Give students a solid foundation in genetic terminology and concept. This knowledge may be applicable to current health situations in students’ lives or can be built upon to understand future health challenges and participate knowledgeably in political discussions. Enable students to acquire a basic knowledge of the complex ethical dilemmas surrounding the availability and interpretation of genetic testing. Promote understanding of the cultural and economic considerations that influence the availability of genetic testing and the treatment of diseases with genetic components. Students will (Learning outcomes): Be able to understand a pedigree and describe the method of inheritance. Describe the contribution genes make to the development of a specific disease or disorder. Be able to give three examples of economical, cultural, or religious considerations when implementing genetic testing procedures. Be able to describe one area that the United Nations or a large governmental body could provide leadership to regulating the availability of genetic testing and the potential curing of genetic disease to all global citizens. Course Format and Grading: This course will 1) utilize a lecture format to teach core concepts, 2) genetic interactives and case study examples to demonstrate and apply the core concepts, and 3) animations and videos to complement the lecture and textbook content. The first segment of each class period will be given in a lecture format while the second segment will be a discussion of the topic covered with an emphasis on personal experiences and practical implementations. Student led discussions of a NY Times article will also take place during the second half of the class period. Exams will include multiple choice questions and short essays. Exams will cover at least these three components: Exam I: Students will define critical genetic terms and interpret the method of inheritance of a family pedigree and describe the basic methods of inheritance. Exam II: Students will be given a major disease and required to describe contributing genetic components, areas of risk worldwide, and environmental, diet, or pharmaceutical interventions that are available. Exam III: Personal essay on the global economic and ethical implications of genetic testing, at-risk assessments and potential curing of genetic-based diseases. Grading: Points will be assigned as follows: Exam 1 Exam 2 Exam 3 Pre Test Post Test Case Studies (5/20 pts) Newspaper article Comments (3/20) Group presentation on Global Issue Writing Essay Lecture and Discussion Schedule: Instructor Week 1 1 1/24 Certel 2 1/26 Certel Genomes 60 pts 60 pts 600 pts Ch. Topic 1 1,13 What is Genetics? Genes, Chromosomes, Certel 1,9 DNA Structure and Certel 10 Gene Action: From DNA to 2/7 Certel 10 Gene Action: From DNA to 2/9 Certel 12 Gene Mutations Certel 2 Gene Relationships: Families, Certel 11 Gene Transmission, Certel 4,6 Understanding Crosses and Certel 7 Effects of Multiple Genes, Week 2 1 1/31 Replication 2 2/2 Protein Week 3 1 Protein 2 100 pts 100 pts 100 pts 10 pts 10 pts 100 pts 60 pts Week 4 1 2/14 IndividualsInheritance 2/16 Epigenetics Week 5 1 2/21 Pedigrees 2 2/23 Review Week 6 1 2/28 2 3/1 Response Week 7 1 3/6 2 3/8 Week 8 1 3/13 Factors 2 3/15 Week 9 1 3/20 2 3/22 Exam I – Genes, Mutations, and Inheritance Woodahl (BMED) Gene Variation and Drug Certel Putnam (BMED) Genetic Testing I Risk Factors Lodmell (BIOL) HIV infection and Risk Wetzel (BIOL) Pesticides and Risk Factors Certel Certel Group Assignment Genes and Cancer Week 10 1 Disease 3/27 Exam II – Genes, Genetic Testing, the Environment, and 2 3/29 Sommers-Flanagan(COUN) Cultural Considerations in Treating Depression Week 11 1 4/10 (Aggression) 1 4/12 Global Issue Certel Behavioral Genetics McCaffrey Writing Center: Essay on 4/17 Putnam (BMED) Ethical Issues and Public 4/19 Prescott (State Farm) Genetic Risks and Insurance Week 13 1 2 4/24 4/26 Certel Student led Discussion Global Issues Global Issues Week 14 1 2 5/1 5/3 Student led Discussion Certel Global Issues Review Exam III Ethical and Cultural Implications of Genetic Testing Week 12 2 Health 2