Cardiovascular Disorders Hypertension p671 • Ateriosclerosis • “silent killer” • Heart muscle can die due to lack of Oxygen • Increases chances of CVA: cerebral vascular accident Coronary Artery Disease • Accumulation of plaque buildup on walls of arteries. • arteriosclerosis Heart Attack • Mycardial infarction • Caused by an obstructured vessel in heart thrombus, embolus • deprivation of oxygen (normally…body releases hypoxia induced factor which stimulates angiogenesis) • If angiogenesis isn’t successful…part of heart dies Heart Attack Animation • http://www.healthcentral.com/cholesterol/u nderstanding-cholesterol-13-115.html • http://www.medindia.net/animation/heart_a ttack.asp Pericarditis • Inflammation of pericardial sac due to viral or bacterial infection • Chest pain, interferes with heart movements Mitral Valve Prolapse • One or both cusps of mitral valve stretches and bulges into left atrium during ventricular contraction • Blood can regurgitate into the left atrium • Palpitations, fatigue, anxiety, chest pains • associated with arrhythmias (atrial fibrillation) that may progress Familial Amyloidosis • Amyloid protein deposits into heart • Causes chest pain, failure of cardiac muscles, disturbance of heart rhythm • the deposits physically disrupt tissue architecture; some cases lead to cell death • WHY? calcium ion concentration imbalances • Ultrasound: echocardiogram can detect Transposition of Great Arteries