CDC’s CDC’s Futures Futures Initiative Initiative CDC’s Health Protection Research Initiative st Century Health Protection in the 21st Achieving maximum health impact is the driving force Two overarching health protection goals – Health protection of people in all communities through preparedness • Infectious disease threats • Environmental threats • Terrorism threats – Health protection through health promotion and prevention of disease, disability and injury • People in all communities will achieve their expected life span with the best possible quality of life in every stag Tanja Popovic, MD, PhD, FAAM Acting Associate Director for Science Centers for Disease Control and prevention Death …. Illness… Public Health Research Workgroup – Phase I Requests for Applications FY2004 Health …. Office of Public Health Research Life …. Public Health Research Workgroup – Phase II 1 CDC’s CDC’s Futures Futures Initiative Initiative Areas of Emphasis Public Health Research Workgroup Charge Develop a set of strategic directions for CDCCDC-wide research agendaagendasetting process addressing the following: • Research issues and needs that are priorities for CDC’s customers and consistent with departmental policies for an intraintra-agency stewardship of the health research enterprise • Ways in which CDC needs to adapt its current practices in conducting and supporting public health research • Assurance that CDCCDC-sponsored research is being effectively applied by practitioners and policymakers Input Guiding Principles • Public health research agenda needs to be developed in concert with the agency’s overall health protection goals. Public Health Research Workgroup deliberations Outside-in approach: meetings conferences consultations Fast Track Process & Fast track Meeting • Gaps in knowledge needed to achieve those goals will be primary driver of research agenda. • Research agenda will be set with external participation. Other FI Workgroups Excellence in Science Committee Public Health Research Workgroup Options and Recommendations Key Strategic Issues Strategic Direction for AgendaAgenda-setting Process Consultancies with Dr. Gerberding & CDC senior staff Agenda-setting Process Agenda Agenda-setting Step 1. Develop a broad public health research framework Step 2. Generate a list of possible research priorities Step 1 Public Participation Option 1 Option 2 Option 3 Step 3. Obtain input from broad range of outside groups and CDC staff Step 4. Synthesize input and generate a draft agenda Step 5. Obtain broad public review of draft agenda Level of Specificity Criteria Step 2 Step 3 Step 4 Step 5 Step 6 Step 6. Revise and finalize document 2 Step 1. Research-toResearch to-practice Cycle Research-to-practice Level of Specificity Levels • Attempts to consider research needs which might arise in each of several phases of the PH approach to population health problems • Early phase – problem identification and search for causes • MidMid-phase – design and implementation of interventions • Late phase – evaluation Disease, Injury or DisabilityDisability-related CrossCross-cutting topics 1. Broadest Chronic diseases Genomics 2. Very broad Cancer Public health genomics 3. Broad Breast cancer Genetic screening 4. Specific Effectiveness of interventions to prevent breast cancer Effectiveness of family screening programs 5. Very specific Effectiveness of mammography Effectiveness of computercomputerbased family screening programs 6. Most specific Effectiveness of mammography in women 4040-49 yrs of age Effectiveness of computercomputerbased family screening programs among Medicaid populations Public Participation • Breadth of participation: How broad? Who plays? -- health organizations considered as traditional partners -- new health and nonnon-health related organizations -- lay representatives from communitycommunity-based individual public • Depth of engagement: How intense? At what level? level? -- inform -- consult -- involve -- collaborate -- empower CDC Public Health Research Agenda for FY 2004 Criteria Option 1. Core set of criteria linked to CDC’s mission -- public health need -- potential impact -- relevance Option 2. Option 1 and widely accepted national goal -- reduction of health disparities and widely accepted unmet need -- crosscross-cutting across the CIOs Requests for Application (RFAs) for FY 2004 Overall goal for all RFAs is to influence priority health protection research addressing the following: Health protection of all people in all communities through preparedness for • Infectious disease threats • Environmental threats • Terrorism threats Health protection through health promotion and prevention of disease, disability and injury assuring that: Expert Panel “Fast Track” Meeting • People in all communities will achieve their expected life span with the best possible quality of life in every stage November 2003 3 Career Development (KO1) (KO1) InvestigatorInvestigator-initiated (RO1) $ 14M for 2020-40 grants $ 10M for 2020-30 grants Purpose To support investigatorinvestigator-initiated public health research projects that have a high probability of influencing priority public health research. research. Research objectives •This year priority is given to research that identifies innovative costcost-effective health promotion policies, programs and activities in the workplace or that affect the workplace. •Future funding cycles will expand this initiative to address health protection research relevant to other populations and sectors. Strategy Purpose To support intensive supervised career development experience for for researchers in a variety of disciplines engaged in all types of public health health research that have a high probability of influencing priority public health issues. Research objectives To develop qualified, experienced, and sustainable cadre of independent independent public health researchers to support nation’s and CDC’s public health priorities. priorities. Design and evaluation of interventions and identification of determinants determinants affecting the successful implementation of evidenceevidence-based costcost-effective interventions in the workplace or that have impact on the workplace. Institutional Training Career Development (KO1) and Institutional Training Strategies $ 4M for 22-4 grants Etiology and needs Social, ecologic and developmental determinants of health Determinants of individual behaviors that impact health Assessing impact of social trends on population health needs Purpose Prevention To develop or enhance training opportunities for individuals, selected selected by the institution, who are training for careers in specified areas of public health research that that have a high probability of influencing priority priority public health issues. Determinants of successful implementation of evidenceevidence-based interventions Reduction of health disparities Effectiveness of communitycommunity-based interventions Application of genetic information to population health Research objectives To ensure a continuing supply of wellwell-trained scientists prepared to lead efforts in conducting cuttingcutting-edge public health research. Methods and Infrastructure Impact of infrastructure and policy alternatives on health outcomes outcomes Economic factors and health Improved surveillance methods Early detection of public health risks Communication strategies Workforce needs and training issues Centers of Excellence in Health Promotion Economics $ 1M for 1 grant Purpose To develop institutional capacity in Heath Promotion Economics. Research objectives To explore economic barriers, priorities, solutions and impact (including (including costcosteffectiveness) of developing, evaluating and implementing health promotion guidelines, recommendations, policies and programs to prevent disease, disease, injury and disability so that all people can achieve their expected life life span with the best possible quality of health at every life stage. Strategies Linking key academic, public and private entities across disciplines disciplines Conducting and facilitating Health Promotion Economics research Providing Health Promotion Economics training. training. 4 Office of Public Health Research A. Research Oversight, Strategy, and Evaluation A. Research Oversight, Strategy, and Evaluation 1. Establish Public Health Research Priorities 2. Develop a Balanced Research Portfolio • Establish and maintain CDC research agenda • Facilitate research agenda processes • Translate agenda into strategic plan for research • Translate strategic CDCCDC-wide goals into scientific goals • Ensure balance of research between intramural and extramural • Build focus on outcomes into research planning process 5 A. Research Oversight, Strategy, and Evaluation 3. Evaluate Research Progress and Outcomes • • • • Work on developing evaluations Quality – Use of peer review Relevance – Conduct relevance review Performance – Track research outcomes. Develop research metrics B. Extramural Research and Peer Review • Develop scientific policy for CDC extramural research and peer review • Provide guidance on extramural issues • Develop centralized peer review capabilities • House CDCCDC-wide crosscross-cutting grants program Futures Initiative Stage II: Implementation Teams • The Organizations Design How we can work faster; be more connected across our agency and with our partners; how we can better respond to our customers needs • The Health Protection Goals • The Strategic Imperatives Public Health Research Implementation Team Implementation of recommendations form the initial 4 Workgroups • The Business Services Improvement Improve our business practices and help create performanceperformance-based culture at CDC Two Component Team Structure Core • Team • • Leadership for overall effort Specific charge to Action Teams Responsible for action implementation Action Team Action Team • • Propose innovative programs and initiatives that support workgroup recommendations Present best ideas and Action collaborate with other Action Teams Team and the Core Team to arrive at “best in class” programs and initiatives Major Charge Action Team Core Team Action Team • Defining public health research agenda and coordination with the agency’s overall health protection goals • Implementation of agenda - setting process Action Team 6 CDC ‘treasures” Social determinants of health Workforce Scientific creativity and synergy Information technology and systems to support science Measuring the impact of research 7 http://www.cdc.gov/futures 8