Program Director/Principal Investigator (Last, First, Middle):
Gill, Harvinder, Singh
BIOGRAPHICAL SKETCH
NAME
POSITION TITLE
Gill, Harvinder Singh
Assistant Professor of Chemical Engineering
Texas Tech University
EDUCATION/TRAINING
INSTITUTION AND LOCATION
Panjab University, Chandigarh, India
Georgia Institute of Technology, Atlanta, GA
Emory University, Atlanta, GA
DEGREE
(if applicable)
B.S.
Ph.D.
Postdoctoral
training
YEAR(s)
1994
2007
2007-2009
FIELD OF STUDY
Chemical Engineering
Bioengineering
Microbiology and
Immunology
A. Positions and Honors
Positions and Employment
Academic
2009 Assistant Professor of Chemical Engineering, Texas Tech University, Lubbock, TX
Industry
1994 - 1997
Engineer – Plant Operations and Safety, Engineers India Limited, Delhi, India
1997 - 2001
Founding Partner, Guru Arjan Dev Chemicals, Chandigarh, India
Honors
1993
1994
2005
2005
2006
2008
st
Silver Medal -1 position in university chemical engineering examination
st
Arun Modi Gold Medal and University Medal - overall 1 position in chemical engineering class of 1994
Nerem International Travel Award
Systems Biology Training Fellowship (funded by NIH)
Best Doctoral Paper Award - Science Applications International Corporation (SAIC)
Sigma Xi Best Thesis Award (amongst all science/engineering thesis at Georgia Tech)
B. Peer-reviewed publications, patents, book chapters and conference abstracts (in chronological order)
Peer-reviewed publications
1. W Martanto, SP Davis, NR Holiday, J Wang, HS Gill and MR Prausnitz, “Transdermal delivery of insulin using
microneedles in vivo”. Pharmaceutical Research, 2004, Jun. 21(6): p. 947-952.
2. HS Gill and MR Prausnitz, “Coated microneedles for transdermal delivery”. Journal of Controlled Release, 2007,
Feb. 117: p. 227-237.
3. HS Gill and MR Prausnitz, “Coating formulations for microneedles”. Pharmaceutical Research, 2007, Jul. 24(7):
p.1369-1380.
4. HS Gill and MR Prausnitz, “Does needle size matter?”. Journal of Diabetes Science and Technology, 2007, Sep.
1(5): p.725-729.
5. J Jiang, HS Gill, D Ghate, BE McCarey, SR Patel, HF Edelhauser and MR Prausnitz, “Coated microneedles for
drug delivery to the eye”. Investigative Ophthalmology and Visual Science, 2007, Sep. 48(9): p. 4038-43.
6. HS Gill and MR Prausnitz. "Pocketed microneedles for drug delivery to the skin". Journal of Physics and Chemistry
of Solids, 2008, 69: p. 1537-1541
7. DP Wermeling, SL Banks, DA Hudson, HS Gill, J Gupta, MR Prausnitz and AL Stinchcomb. "Microneedles permit
transdermal delivery of a skin-impermeant medication to humans ". Proceedings of the National Academy of
Sciences (PNAS), 2008, Feb. 105(6): p. 2058-2063.
8. HS Gill, D Denson, B Burris and MR Prausnitz, “Effect of microneedle design on pain in human subjects”. Clinical
Journal of Pain, 2008, Sep. 24(7): p.585-594
PHS 398/2590 (Rev. 11/07)
Page
Biographical Sketch Format Page
Program Director/Principal Investigator (Last, First, Middle):
Gill, Harvinder, Singh
9. SL Banks, RR Pinninti, HS Gill, PA Crooks, MR Prausnitz and AL Stinchcomb, “Flux across microneedle-treated
skin is increased by increasing charge of naltrexone and naltrexol in vitro”, Pharmaceutical Research, 2008
Jul;25(7):1677-1685
10. Q Zhu, VG Zarnitsyn, L Ye, Z Wen, Y Gao, L Pan, I Skountzou, HS Gill, MR Prausnitz, C Yang, and RW
Compans, "Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge".
Proceedings of the National Academy of Sciences (PNAS). 2009, 106: p. 7968-7973
11. HS Gill, S Andrews, S Sakthivel, A Fedanov, I Williams, D Garber, F Priddy, S Yellin, M Feinberg, S Staprans and
MR Prausnitz, "Selective removal of stratum corneum by microdermabrasion as a novel method of transdermal
drug delivery". European Journal of Pharmaceuticals (In press).
Patents
HS Gill and MR Prasunitz (2006) Coated microstructures and method of manufacture thereof, PCT International Patent
Application No. PCT/US2006/023814. Patent has been licensed to Apogee Technology, USA.
Book chapters
MR Prausnitz, HS Gill and J-H Park, “Microneedles for drug delivery, in Modified Release Drug Delivery, 2nd edition,
MJ Rathbone, J Hadgraft, MS Roberts and ME Lane, eds., Informa Press, New York
Book reviews
HS Gill, "Skin Delivery Systems: Transdermals, Dermatologicals and Cosmetic Actives" (John J. Wille, Ed., Blackwell
Publishing Professional, Iowa, 2006) Pharmaceutical Technology, 2007 March: p. 106.
Conference abstracts
1. W Martanto, SP Davis, NR Holiday, J Wang, HS Gill and MR Prausnitz, "Transdermal delivery of insulin using
microneedles in vivo". Proceedings of the 30th International Symposium on Controlled Release of Bioactive Materials
(2003).
2. HS Gill and MR Prausnitz, "Microneedle technology for transdermal drug delivery with minimal pain". Proceedings of
the Conference on Profit from the Injectables & Self-Injectables Market (2004), Philadelphia, PA, USA.
3. MR Prausnitz, SP Davis, HS Gill, JH Park, W Martanto, PM Wang and MG Allen Rational Design of microneedles for
transdermal delivery, Proceedings of the American Institute of Chemical Engineers Annual Meeting (2004).
4. Stumpp, AJ Welch, HS Gill, and MR Prausnitz, "OCT analysis of microneedle and Er: YAG surface ablation for
enhanced transdermal delivery of hyperosmotic agents for optical skin clearing". Proceedings of SPIE, 2004, Vol:
5319 - Laser Interaction with Tissue and Cells XV: p. 121-129.
5. SL Banks, RR Pinninti, HS Gill, MR Prausnitz, and AL Stinchcomb, "In vitro permeation studies of naltrexone base
and hydrochloride with microneedle-treated hairless guinea pig skin", 32nd Annual Meeting of the Controlled Release
Society (CRS, 2005), Miami, FL, USA.
6. SO Choi, JH Park, Y Kim, HS Gill, Y Choi, MG Allen and MR Prausnitz, "Microneedle electrode array for
electroporation of skin for gene therapy", 32nd Annual Meeting & Exposition of the Controlled Release Society (CRS,
2005), Miami, FL, USA.
7. HS Gill and MR Prausnitz, "Drug and vaccine-voated microneedles for delivery to skin", 32nd Annual Meeting of the
Controlled Release Society (CRS, 2005), Miami, FL, USA.
8. SO Choi, JH Park, Y Choi,Y Kim, HS Gill, Y-K Yoon, MR Prausnitz, and MG Allen, "An electrically active microneedle
array for electroporation of skin for gene delivery". Proceedings of the 13th International Conference on Solid-State
Sensors, Actuators and Microsystems, pp. 1513-1516.
9. HS Gill and MR Prausnitz , "Transdermal drug delivery via coated microneedles", AIChE Annual Meeting (2005),
Cincinnati, OH, USA.
10. J Jiang, D Ghate, HS Gill, BE McCarey, DH Geroski, HF Edelhauser, and MR Prausnitz, "Microneedles for ocular
drug delivery". 33rd Annual Meeting of the Controlled Release Society (CRS, 2006), Vienna, Austria.
11. HS Gill and MR Prausnitz, "Microneedles for minimally invasive transdermal drug delivery". Proceedings of the
Conference on Drug Delivery (2006), San Diego, CA, USA.
12. HS Gill, D Denson and MR Prausnitz, "Effect of microneedle design on pain in human subjects", 33rd Annual Meeting
of the Controlled Release Society (CRS, 2006), Vienna, Austria.
13. HS Gill, A Fedanov, SN Andrews, S Sakthivel, I Williams, F Priddy, MR Prausnitz and S Staprans,
"Microdermabrasion of skin to target cutaneous dendritic cells for MVA-based AIDS vaccines". Proceedings of the
AIDS Vaccine 2006 International Conference, Amsterdam, Netherlands.
14. HS Gill, J Sõderholm, I Skountzou, R Compans, J Jacob, M Sãllberg and MR Prausnitz, "Immunization via skin using
vaccine-coated microneedles", AIChE Annual Meeting (2006), San Francisco, CA, USA.
15. HS Gill, D Denson and MR Prausnitz, "Effect of microneedle design on pain in human subjects", AIChE Annual
Meeting (2006), San Francisco, CA, USA.
PHS 398/2590 (Rev. 11/07)
Page
2
Continuation Format Page
Program Director/Principal Investigator (Last, First, Middle):
Gill, Harvinder, Singh
16. HS Gill, A Fedanov, S Sakthivel, I Williams, S Staprans and MR Prausnitz, "Microdermabrasion of skin for drug and
vaccine delivery", AIChE Annual Meeting (2006), San Francisco, CA, USA.
17. HS Gill and MR Prausnitz, "Coated microneedles for transdermal delivery", AIChE Annual Meeting (2006), San
Francisco, CA, USA.
18. DP Wermeling, S Banks, HS Gill, MR Prausnitz and A Stinchcomb, "Successful transdermal delivery of a skin
impermeable molecule using microneedles", ACCP Anuual Meeting (2007), Denver, CO, USA.
19. J Jiang, SR Patel, HS Gill, D Ghate, BE McCarrey, DH Geroski, HF Edelhauser, and MR Prausnitz, "Ocular drug
delivery using microneedles", The Association for Research in Vision and Ophthalmology Annual Meeting (2007), Fort
Lauderdale, FL, USA
20. SL Banks, DP Wermeling, HS Gill, MR Prausnitz and AL Stinchcomb, "Microneedle Enhanced Skin Permeation of
Naltrexone Hydrochloride in Human Volunteers", AAPS Annual Meeting (2007), San Diego, CA, USA.
21. J Jiang, SR Patel, HS Gill, D Ghate, BE McCarey, DH Geroski, HF Edelhauser and MR Prausnitz, "Ocular Drug
Delivery Using Microneedles", AIChE Annual Meeting (2007), Salt Lake City, UT, USA.
22. J Gupta, HS Gill, SN Andrews, and MR Prausnitz, "Kinetics of skin resealing after insertion of microneedles in human
subjects", Trailblazing the Skin Frontier Meeting, Gordon Research Conference (2007), Newport, RI, USA.
23. M Milewski, SL Banks, HS Gill, MR Prausnitz, and AL Stinchcomb, "Microneedle-enhanced transdermal delivery of
ionized species", American Association of Pharmaceutical Scientists Annual Meeting (2007), San Diego, CA, USA.
24. J Gupta, HS Gill, SN Andrews, and MR Prausnitz, "Kinetics of skin resealing after insertion of microneedles in human
subjects", Barrier Function of Mammalian Skin Meeting, Gordon Research Conference (2007), Newport, RI, USA.
25. SR Patel, J Jiang, HS Gill, D Ghate, BE McCarey, DH Geroski, HF Edelhauser, and MR Prausnitz, "Ocular drug
delivery using microneedles", AIChE Annual Meeting (2007), Salt Lake City, UT, USA.
26. HS Gill, J Soderholm, B Burris, D Denson, M Sallberg and MR Prausnitz. "Microneedles For Painless Vaccination In
Mice And Human Subjects", AIChE Annual Meeting (2007), Salt Lake City, UT, USA.
27. HS Gill, S Andrews, A Fedanov, S Sakthivel, I Williams, D Garber, F Priddy, M Feinberg, S Staprans and MR
Prausnitz, "Selective removal of stratum corneum by in vivo microdermabrasion for transdermal delivery", AIChE
Annual Meeting (2007), Salt Lake City, UT, USA.
28. SR. Patel, NJ Jiang, HS Gill, D Ghate, BE. McCarey, DH Geroski, J Nickerson, HF Edelhauser and MR Prausnitz,
"Microneedles for ocular drug delivery", Ophthalmic Drug Delivery Conference (2008).
29. SN. Andrews, E Jeong, HS Gill, and MR Prausnitz, "Transdermal delivery of proteins using microdermabrasion", 35th
Annual Meeting & Exposition of the Controlled Release Society (2008)
30. J Gupta, S Andrews, HS Gill, and MR Prausnitz, "Kinetics of skin resealing after insertion of microneedles in human
subjects", 35th Annual Meeting & Exposition of the Controlled Release Society (2008)
31. SR Patel, NJ Jiang, HS Gill, D Ghate, BE McCarey, DH Geroski, J Nickerson, HF Edelhauser, and MR Prausnitz,
"Microneedles for ocular drug delivery", Society for Biomaterials Fall Symposium (2008).
32. HS Gill, B Wang, FS Quan, SM Kang, C Yang and RW Compans, "Virus-like particles as a platform for novel
bionanomaterials", AIChE Annual Meeting (2008), Philadelphia, PA, USA
33. HS Gill, FS Quan, SM Kang, RW Compans, "Adjuvant characterization for virus-like particle-based influenza
vaccines", AIChE Annual Meeting (2008), Philadelphia, PA, USA
C. Professional Service
2007-Present
Active reviewer for Journal of Controlled Release
2007
Co-chaired conference session, “Nanotechnology for Biotechnology and Pharmaceuticals Industries”,
AIChE Annual Meeting (2007), Salt Lake City, UT, USA.
2004 - 2005
Founder Chair of Bioengineering Graduate Student Advisory Committee at Georgia Institute of
Technology
2003 - 2004
Member of bioengineering program review committee reporting to the dean of engineering at Georgia
Institute of Technology
PHS 398/2590 (Rev. 11/07)
Page
3
Continuation Format Page