!!!GLAND!!! HUGE PARTY THIS WEEKEND!! The Anterior Pituitary Gland is putting on a hot party this weekend. Below are directions, where it is, as well as some hormones that it’ll be secreting! So don’t miss out! Growth Hormone (GH): Will be enabling protein synthesis as well as muscle and connective tissue growth so there will be plenty of action going on! Adrenocorticotropic (ACHT): Causes the adrenal cortex to make corticosteroid hormones, which regulate blood glucose, making everyone WILD with excitement Thyroid-Stimulating Hormone (TSH): Enables the thyroid gland to produce thyroxin Luteinizing Hormone (LH): Used in ovulation and forming the corpus luteum, as well as for stimulating the testes to produce testosterone. So everyone keep a tight hold on his or her significant other. Prolactin (PRL): Produces milk by stimulation the mammary glands as well. Plenty of drinks to go around! Follicle Stimulating Hormone (FSH): Used in the development of ovarian follicles Growth Hormones With A Sick Problem Speak Up and sperm. Directions: Driving Towards the Hypothalamus and go beneath it, it’s only a little ways back in an area called sella turcica, which is at the base of the skull. For the First Time! When the going gets bad, the bad gets growing, or something like that in the case of Robert Wadlow. On February 22, 1918, this gigantic boy was born at a normal eight pounds six ounces, but by the time he was eight years old, he weighed 192 lbs and was six feet two inches tall in height. Not quite normal on the scale of most eight year olds. By the time he was 22, Wadlow died of complications due to his disease, gigantism, at the height of 8 feet 11 inches! GLAND went to the source of his unusual growth hormone excess to discuss with them what went wrong in Wadlow. We landed at the growth hormones home, the Anterior Pituitary Gland, where the hormones are produced and secreted. Although at first, the hormones didn’t want to talk, they soon opened up and released their story. For as long as they could remember, things at home had always been unusual. The Anterior Pituitary gland seamed to require more work from the GH’s (Growth Hormones) then they could recall any of the other Anterior Pituitary Glands requiring. But they didn’t complain, and began producing so much of themselves that by the time Wadlow was a year old, he weighed 30 lbs. None of the guys seam to think anything was really wrong, maybe their gland was more strict than others, and everyone didn’t mind the extra work. But by the time Wadlow was five and was well into Five feet tall, they knew something was wrong. But no one could stop. They had set themselves into a whirlwind of havoc, believing they needed to produce several times the amount then they needed to in an average person. But the need to produce was so strong they could do nothing to resist it. The Anterior Pituitary Gland kept requesting more and more GH and soon things were totally out of control. “You don’t know what its like to feel like all that matters in your life is to make more, make more,” says one GH with teary eyes. “That was all that mattered, that was what I lived for.” Though Wadlow died, the Growth Hormones have spoken up about their problem and are currently trying to help other hormones and glands with this same problem. If you think you or a loved on is in need of help, you can contact them at 1800-GRO-HELP Information kindly provided by: http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/hypopit/ http://www.thehormoneshop.com/pituitarygland.htm http://www.becomehealthynow.com/article/bodyendocrine/734/ and http://psych.unn.ac.uk/users/nick/hormonespp02/tsld012.htm This Newsletter is created by: Katie Duvall Marian Hawley And Katie Wilson Ralph Wadlow standing next to his brother. Prolactin: The Real Story Prolactin has had a lot going on in its life recently. Lately with the news that its not only produced in the Anterior Pituitary gland but in many, many different areas in the body. But now it would like to come out and really describe the effects and relationship it has with its organs it effects. G: So what organ do you primarily affect? P: Its not so much an organ as it is a gland. I affect the mammary gland, inducing it to produce milk, but of course only in mammals. G: How does this work? P: I induce lobuloalveolar growth of the mammary gland, or the Alveoli, which are the cells of the gland that actually secrete milk. G: Very Interesting P: And I also stimulate lacto genesis or milk production after giving birth. G: That must be hard work, is there anything makes you realize when its time to stop producing? P: Well I’ve become friends with Dopamine who’s been helping me to realize when to stop producing, so I’ve been doing really well not over secreting G: Well that’s great. It was wonderful talking to you, I hope we can meet again in the future. P: I would love to! And thank you!