Questions for you Introductions to Genetics Mendel and all that… that… Who Is This?? In your notes, answer these ?s: • Who in your family do you most look like? like? • In what ways do you NOT look like that person? • Who in your family has interests and preferences most like yours? Mrs. Hunter’s relative…. Which relative? Yep, you guessed it… It’ It’s Mrs. Hunter’ Hunter’s……. ……. I. Some terms A. Genetics = study of heredity Grandmother! B. Heredity= Heredity= passing traits to offspring 1 C. Traits What traits do you share? 1. = characteristics that parents can pass to offspring 2. Examples of traits: traits: Eye color Hair color Shape of eyebrows II. Gregor Mendel (1822(1822-1884) 3. What traits do share with your parents? siblings? cousins? B. Mendel’ Mendel’s Work 1. Background a. In peas, ♂ & ♀ parts are in every flower b. Pollen = plant sperm c. SelfSelf-pollination= pollination= flower fertilizes itself d. CrossCross-pollination= pollination= flower fertilized by another flower A. Who was he? z Austrian monk z Studied the traits of pea plants z “Father” Father” of modern genetics http://www.scienceshorts.com/gmendel.htm 1. Background http://www.sciam.com/article.cfm?articleID=F4604E0F-E7F2-99DF-30C88C9489BD83A2 2. Mendel’s Experiments a. Mendel controlled the pea pollination b. ¿ How did he do this? e. Peas have a lot of traits f. Can’ Can’t study them all at once g. Mendel studied one at a time http://fig.cox.miami.edu/~cmallery/150/mendel/heredity.htm 2 2. Mendel’s Experiments 2. Mendel’s Experiments • Removed ♂ parts from a flower • Dusted ♀ parts with pollen from another flower • ¿ Was this self-pollination or cross-pollination? cross-pollination c. First Mendel crossed: purebred purebred white flowered plant x purple flowered plant (P1 generation) (P1 generation) all offspring were purple (F1 generation) 2. Mendel’s Experiments d. Then, he crossed the F1 generation with itself (self(self-cross) F1 X F1 3 offspring were purple 1 was white (F2 generation) 2. Mendel’s Experiments e. What happened? z Did the traits blend? z Why were all the F1 flowers purple? purple? z Why did we get 3 purple & 1 white in F2? http://www.biology.iupui.edu/biocourses/N100/images/heade rnotes.gif 2. Mendel’s Experiments f. Vocabulary we need: z Gene = part of a chromosome that codes for a trait or a protein (we have two genes for every trait) z Allele = a form of a gene E.g. white or purple flowers Vocabulary z Dominant = if present, is always expressed z Recessive = both recessive alleles must be present for expression http://www.healthsystem.virginia.edu/internet/huntdisease/geninfo.cfm http://www.csulb.edu/~kmacd/361-6-Ch2.htm 3 g. Back to Mendel z z z Let B = purple Let b = white P1 x P1 g. Back to Mendel F1 x F1 (self(self-cross) Bb x Bb P1 BB 1 BB (purple) 2 Bb (purple) 1 bb (white) bb F1 Bb 3 purple 1 white http://uz.wikipedia.org/wiki/Genetika http://uz.wikipedia.org/wiki/Genetika http://www.biology.iupui.edu/biocourses/N100/2k4ch10genetics.html Questions z Which allele is dominant? Purple flowers or white flowers? z Did the alleles blend? blend? NO, NO, flowers were either white or purple, but not in between z Why were all the F1 flowers purple? purple? purple is dominant z Why did we get 3 purple & 1 white in F2? purple is dominant More Vocabulary z Homozygous = 2 of SAME alleles for the same trait (BB or bb) z Heterozygous = 2 different alleles for the same trait (Bb) Practice z Copy the table in the Quick Lab on page 166 of the textbook into your notes z Circle your phenotype (physical appearance) for each trait z Count the # in class with each trait z Write the numbers in the boxes Questions How many cleft chins: no clefts? How many dimples: no dimples 3. How many hair above knuckles : hairless fingers? 4. How many freckles: no freckles? 5. For which phenotypes do we know the genotype (which genes are present)? 1. 2. 4 Bibliography Graphics 1. 2. Mendel picture http://www.scienceshorts.com/gmendel.htm 11/3/07 Garden pea picture http://www.sciam.com/article.cfm?articleID=F4604E0F-E7F2-99DF-30C88C9489BD83A2 11/3/07 3. 4. 5. 6. 7. Pea characters http://fig.cox.miami.edu/~cmallery/150/mendel/heredity.htm 11/3/07 F1 cross http://www.biology.iupui.edu/biocourses/N100/2k4ch10genetics.html 11/3/07 Punnett Square http://uz.wikipedia.org/wiki/Genetika 11/3/07 Alleles http://www.csulb.edu/~kmacd/361http://www.csulb.edu/~kmacd/361-6-Ch2.htm 11/4/07 DNA, genes, chromosomes http://www.healthsystem.virginia.edu/internet/huntdisease/geninfo.cfm http://www.healthsystem.virginia.edu/internet/huntdisease/geninfo.cfm 11/4/07 5