IN THIS ISSUE: • Student Internships: Kiel Tietz Noah Holzman • Alumni Update: Megan Nordquist • Study Abroad: Christina Basch Keeping Applied Science Alumni Informed » Spring 2012 Dear Alums, As another academic year draws to a close, I look back at the accomplishments and progress of the Applied Science program and can happily report that growth continues to be a distinguishing characteristic. For example, 28 students received their APSC degrees on May 12th, bringing the total number of graduates to 130. I’m sure some of you can remember when that number was in single digits. Many of these new graduates will be pursuing health-related careers to become pharmacists, chiropractors, physician assistants, veterinary assistants and histotechnologists. Others have chosen graduate school for master’s or Ph.D level programs while some are heading for careers in labs, both indoor and outdoor. Current students are distinguishing themselves through participation in research as evidenced by selection for the annual Posters in the Rotunda event, and the UW System Symposium for Undergraduate Research and Creative Activity. Students continue to actively participate in professional organizations such as the Sustainable Agriculture Education Association and the Materials Research society, with the addition of the vibrant new Pharmacy Club. Trying to keep up with alumni careers and activities has been one of my favorite pursuits though there’s never enough time. Now that my role as program director is coming to an end, hopefully I won’t lose touch, though I won’t be bugging you as much about coming back to give a presentation at a seminar. That will be Dr. Ann Parsons’ role as she becomes program director. Dr. Parsons brings a wealth of experience and passion for teaching science to the position and will be an asset as the program continues to develop. Please support her efforts to maintain a quality program, especially if she contacts you for advice or information about your respective careers. It’s been fun! B.S. in Applied Science Program Dear Applied Science Alumni, I am looking forward to taking up the role of Applied Science program director and hope to continue developing the program so ably handled by Dr. Bomar over the past seven years. He leaves a legacy of commitment to our students that has been the guiding principle for all Applied Science faculty and staff. I hope to help carry that commitment forward as we face new challenges and opportunities. Please don’t be surprised if I call on you for input and suggestions to help us keep the program moving forward! Sincerely, Inspiring Innovation. Learn more at www.uwstout.edu/programs/bsas Kiel Tietz Student Internship: Ohio State REU My name is Kiel Tietz and I am currently a senior in the Applied Science program at UW–Stout. Over the 2011 summer, I participated in Ohio State University’s Molecular Genetics Research Experience for Undergraduates (REU), funded by the National Science Foundation (NSF). The program was nine weeks long and was critical to my growth as an independent researcher. From my involvement, I became knowledgeable in many valuable practices such as laboratory presentations and article interpretation. My research was conducted in Dr. Andrea Doseff’s laboratory and focused on cellular death through apoptosis. My project was titled Mapping Peptides Responsible for the Interaction between Heat Shock Protein 27 and Caspase-3. It had recently been discovered that heat shock proteins (Hsps) have the ability to chaperone caspases and ultimately regulate apoptosis. The small heat shock protein 27 (Hsp27) specifically holds control of apoptosis through halting the autocatalytic cleavage of caspase-3. My lab had previously researched Hsp27’s capacity to inhibit apoptosis and discovered peptides of the C-terminal domain were responsible for preventing the autocatalytic cleavage. To further investigate the interaction between Hsp27 and caspase-3, I generated five serial deletions of the C-terminal domain, each omitting a successively larger peptide sequence. The Hsp27 deletion constructs were transfected into HeLa cells and through immunoprecipitation, association with caspase-3 was determined. This research was significant to further understand mechanisms regulating apoptosis through caspase interactions. I learned much about myself from this summer REU. I absolutely now know I want to pursue a Ph.D. degree and I have narrowed my interests down to cellular and developmental biology. I now feel much more comfortable in a laboratory setting and can foresee my career within one. The REU program at Ohio State was an amazing experience that was well paid and operat- “I now feel much more comfortable in a laboratory setting and can foresee my career within one. ... I believe any rising scientist should take advantage of these research opportunities and apply to as many as possible.” Kiel Tietz ed. I believe any rising scientist should take advantage of these research opportunities and apply to as many as possible. They look great on the resume and more importantly give you priceless connections. Overall the hours were long but I had great enjoyment doing something I’ve desired for years! Noah Holzman Student Internship: Coe College REU I am Noah Holzman, and I’m a sophomore here at Stout. I am an Applied Science major with a concentration in Materials Science. This summer I was allowed the opportunity to live and work at Coe College in Cedar Rapids, Iowa through the NSF REU program. Although Coe’s population is a mere 1,300 students, it has a world-renowned glass research lab, thanks to S. Donald Stookey, the inventor of CorningWare, who did his undergraduate studies there. I never imagined that I would be working in a research lab the summer after my freshman year, but I applied anyway, and I am certainly glad that I did! My research last summer was focused on the structure of binary (two component) glasses. Since the molecules in glasses are much more disorganized than other solids, they are more difficult to classify and explain. This makes them very interesting to research. I made glasses by mixing powdered chemicals together in various ratios, heating them in a very hot furnace and cooling the liquid. Next, the glass is crushed into a powder. The main instrument I used for analysis hits the powdered glass sample with a powerful laser beam, which ejects ions from the surface of the glass. These ions fly down a tube and hit a detector, and the data can be interpreted to show what kinds of molecules make up the glass. Knowing what makes up the sample helps in explaining why the glass has the physical properties that it does. Making glasses with different ratios of the starting chemicals can change the abundance of certain molecules, thus changing the physical properties. This information is useful when making “engineered glasses” where a glass is designed with physical properties to meet a certain need or application. My time at Coe was more than just a learning experience. I made many friends and invaluable connections with professors. Living on my own in a new city in a different state was a lot of fun, and I can easily say Noah Holzman “Overall, the REU experience has helped me learn a lot about the research environment. What I have learned and experienced last summer has made me even more confident that working in a research laboratory is right for me.” that it has been the best summer of my life thus far. Overall, the REU experience has helped me learn a lot about the research environment. What I have learned and experienced last summer has made me even more confident that working in a research laboratory is right for me. I encourage all undergraduate students in STEM programs to look into the REU program if they are interested in laboratory work or research. Not only does the program pay well, they usually also provide housing with opportunities all around the country. It is a great opportunity to not only advance your career in science, but also make money, have fun and gain knowledge! Megan Zemke Nordquist Alumni Update Hello to all the past and present Applied Scientists! Since graduating in May of 2009, my life has changed in numerous exciting ways. During my time at Stout I always planned to go on to earn my Masters of Physician Assistant degree after graduating from Stout. After graduation I worked for a year as a Certified Nursing Assistant at Dove Health Care–South in Eau Claire, and became a certified Basic Emergency Medical Technician. In the summer of 2010 I began classes for the Physician Assistant Program at the University of Mount Union in Alliance, Ohio. If any of you guys out there watch football, you would know that Mount Union has played UW-Whitewater in the Division III football championship game every year for about the last seven years. My professors would always tell us that no one would understand what you go through in the PA program besides people that are in the program, and that is 100% true. The program is 27 months long and is continuous year round. Each semester had on average 17 credit hours. The amount of material we had to consume during our didactic year was insane. I read more during that year than I ever did before in my life! I even slept with my “current” book next to my bed at night in case I woke up during the night unable to fall back asleep until I knew the correct treatment plan or gold standard diagnostic study for the patient scenario I was dreaming about. I was elected as the student representative for the Ohio Association of Physician Assistant Board. I served on the board for a year and was able to meet some amazing people. I helped plan a student PA conference in Columbus Ohio for all the PA programs in Ohio and was also able to attend the American Academy of Physician Assistants annual conference in Las Vegas. During this time I was also planning a wedding! I got married in August 2010 to Eric Nordquist, who is also a Stout Alumni. It was very common for my classmates to see me with our medical books on one side of me and invitations on the other side. Just some friendly advice: don’t make your own invitations — it’s a lesser hassle to put someone else in charge of that and the price is worth it! After the 15 months of our didactic year, we had a white coat ceremony, celebrating our accomplishment of the didactic year and entering into the clinical year. We had to complete 10 rotations that were each four Eric and Megan Nordquist “The amount of material we had to consume during our didactic year was insane. I read more during that year than I ever did before in my life!” weeks in duration. Each rotation resolved a different area of medicine. It was exciting to be in the rotations; however it brought on a new type of stressor every four weeks. It felt like a new semester with each rotation and with that a new type of professor to get to know and understand their expectations. By the time you would understand the rotation it was your last day and the new one started in a couple days. Finally, I walked the graduation stage on May 2012 and will have my official graduation ceremony from the program this August! I am currently ending my general surgery rotation and have my Emergency Medicine rotation left to complete, along with my Senior Capstone Project. I plan to work around the Eau Claire area when I move back in with my husband at the end of July. I couldn’t be happier for the things I have been able to complete in my life thus far. I am excited to start a brand new chapter of my life as a working Physician Assistant! Christina Basch Study Abroad: New Zealand Calling Kia Ora! My name is Christina and I am a third year biotechnology student. This past year I decided to study in New Zealand. I left during one of the snowiest winters in Minnesota, to arrive in a lush paradise. After traveling for 46 hours I finally made it to Dunedin, New Zealand, my home for 2011. The countryside was covered with the greenest grass, and littered with sheep. Sheep outnumbered humans seven to one! I enrolled for papers (courses) such as biochemistry, chemistry, nautical studies, archeology, and biology of marine vertebrates. Living a half kilometer away from the ocean allowed me to experience so many different academic opportunities such as dolphin dissections and field trips out on the ocean. Classes were different in that a majority of marks were based on the final exam with little credit for lab and class work. I was also involved with a trace metal research project with the number one Oceanography lab in the world. Dunedin is a university town, with students making up one fifth of the population. There is a rich student culture known as Scarfies, named for the scarves they wear in the winter because houses are not insulated. The university arranged housing complexes for international students that mixed us with New Zealanders so we would get the entire ‘Scarfie’ experience. I lived with people from New Zealand, the UK, Germany, Turkey, Austria, Colombia, among many other countries, and made lifelong friendships. New Zealand is small enough that it is possible to take road trips every weekend. I got to experience the jaw-dropping beauty of Milford Sound, driving on the left side of the road, bungee jumping 134m over the Nevis Gorge, kayaking through the turquoise waters “Living a half kilometer away from the ocean allowed me to experience so many different academic opportunities such as dolphin dissections and field trips out on the ocean.” Christina (second from left) and friends of Abel Tasman, snowboarding in the Southern Alps, hiking the nature reserve Stewart Island, marching into Mordor and climbing atop Mount Doom (Mount Ngauruhoe), and experiencing the 2011 Rugby World Cup (which the All Blacks won for the first time in 13 years)! This country is the perfect place for nature lovers and adrenalin junkies. If I had the opportunity to go back, I wouldn’t hesitate. I met many amazing people, learned many things, and tried new experiences that I never thought I could do. This truly was a life changing trip and I hope one day to return. UW-STOUTKeeping Applied Science Alumni Informed . The goal of this newsletter is to keep alumni in touch with the Applied Science program. Please update your contact information so that we can keep in touch with you in upcoming newsletters. Share this with your other Applied Science alumni that you are in contact with, we would love to keep them informed also. Please mail these contacts to the address on the below or send your updated information at apsc@uwstout.edu. 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