®
USD 3067
Mixing system: PadMixer 1000 system
Mixing biocontainer: 200 L
Application mixing type: Solid-liquid
The PadMixer system is a scalable single-use mixing system. The heart of this mixer is an innovative top-mounted mixing paddle that allows effective and uniform mixing in demanding applications, such as preparation of contained high-solids solutions or mixing of high-viscosity liquids.
Mixing large quantities of a solid and a liquid, such as during the preparation of high-concentration buffer solution, can be challenging for single-use mixing systems. Often, the force needed to suspend the solid can lead to stalling of the impeller.
In this experiment, a PadMixer 1000 system was used to prepare 200 L of a high concentration salt solution. The objective was to demonstrate how the paddle impeller is able to suspend large loads of solid without stalling.
A 200 L mixing biocontainer was filled with 170 L of DI water and 60 kg of solid sodium chloride. After the solid was added and had settled on the bottom of the biocontainer, mixing was started with a paddle speed of 50 rpm and a mix angle of 9°.
Solution homogeneity was determined via conductivity readings taken at the top, middle and bottom of the mixing biocontainer during the mixing process.

Figure 1 shows the solution homogeneity in the biocontainer during mixing.
Mixing was 98% complete within 2 minutes, with steady state reached in 5 minutes.
Figure 1
Mixing efficiency in 200 L biocontainer
100%
80%
60%
40%
20%
Homogeneity at TOP of mix vessel
Homogeneity at MIDDLE of mix vessel
Homogeneity at BOTTOM of mix vessel
0%
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Elapsed Time / Minutes
The paddle mixing action of the PadMixer 1000 system is capable of high mixing efficiency in high-load -solid-liquid applications.
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The information provided in this literature was reviewed for accuracy at the time of publication. Product data may be subject to change without notice. For current information consult your local Pall distributor or contact Pall directly.
© 2015, Pall Corporation. Pall, and PadMixer are trademarks of Pall Corporation. ® indicates a trademark registered in the USA and TM indicates a common law trademark. Filtration.Separation.Solution.
is a service mark of Pall Corporation.
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USD3067