2013 Medical Center STARS Summer Research Program for Students Dagem Adera Andrew Bazley Harmony Science Academy Booker T. Washington HSPVA Host: Denise Marciano, M.D., Ph.D. Host: Jenny Hsieh, Ph.D. Role of p120 Catenin in Regulating Glis2 Function Purinergic Signaling in Isoxazole Driven Neurogenesis Ivette Alvarez Susy Briones Peak Preparatory High School Williams Preparatory Host: Rana Gupta, Ph.D. Host: Ivan D’Orso, Ph.D. Molecular Determinants of Brown and White Adipocyte Development Cancer-Related Mutations in PPM1G Lead to Loss of Phosphatase Function Olatunde Badejo Kevin Chow North Garland High School Coppell High School Host: Michael Shiloh, M.D., Ph.D. Host: Ezra Burnstein, M.D. Discovering Peptide Sequences for Use in a Mimotope Vaccine Generation of Antibody Against Deubiquitinase USP21 Emily Barnes Emanuel Cortes Episcopal School of Dallas School for the Talented and Gifted at Yvonne A. Ewell Townview Center Host: Dean Smith, M.D., Ph.D. Abnormal Courtship Behavior in Male Fruit Flies Lacking Odorant Receptors Or65abc Yesenia Barrios Saginaw HIgh School Host: Zhi-Ping Liu, Ph.D. The Histone Demethylase JMJD2B is Required for Proliferation and Anchorage-Independent Growth of Prostate Cancer Host: Shawn Burgess, Ph.D. Inducing Oxidative Stress in Nicotinamide Nucleotide Transhydrogenase-Enzymatic Deficient C57BL/6 Mice 2013 Medical Center STARS Summer Research Program for Students James Ding Juan Galindo Flower Mound High School Summit International Preparatory Host: Jennifer Kohler, Ph.D. Host: Xiaoying Bai, M.D., Ph.D. Optimization of the Expression and Purification of Recombinant CTxB A Chemical Screen to Study TIF1gamma Function in Zebrafish Hematopoiesis Felonie Doss Trinidad Garza Eearly College High School Host: Ann Stowe, Ph.D. Detraining Minimizes the Protective Influence of Exercise on the Adaptive Immune Mechanisms Joseph Giroux Bryan Adams High School Host: Fan Gao, Ph.D. Development of a ComputerControlled Motorized Device Samya Isa Julian Escamilla Plano East High School Desoto High School Host: Lind Baker, M.D. Host: Sandeep Burma, Ph.D. CDK Inhibition Increases Sensitivity to PARP Inhibitor in BRCA1-Deficient Cancer Cells Cecilia Esquivel School for the Talented and Gifted at Yvonne A. Ewell Townview Center Host: Helmut Kramer, Ph.D. A Genetic Screen for Dominant Suppressors of Drosophila Acinus A Novel Familial Prune Belly Syndrome FLNA Mutation Results in Enhanced β-integrin Binding Jorge Jaimes W.H. Adamson High School Host: Joel Goodman, Ph.D. How Deletion Mutants of Seipin Affect its Localization and Phenotype 2013 Medical Center STARS Summer Research Program for Students Sofia Joison Cecilia Serrano J.J. Pearce High School John A. Dubiski Career High School Host: Ian Corbin, Ph.D. Host: Vitaly Margulis, M.D. Albumin Secretion in Primary Hepatocytes and Liver Cell Lines Methylation-Sensitive High Resolution Melt in the Study of the E-Cadherin Promoter Erik Lamas W. T. White High School Host: Michael Buszczak, Ph.D. Screening of Ovaries in Female Drosophila Melanogaster with Gene Insertions Carolynn Van Zandt Waxahachie High School Host: Benjamin Chen, Ph.D. Characteristics of DNA Repair Function in a Variety of Mouse Embryonic Fibroblasts Lucy Lin Lamar High School Host: Matthew Lewis, Ph.D. Initial Experiences with the Verasonics Ultrasound Research Platform Christy Purnadi R.L. Turner High School Host: Ming-Chang Hu, M.D., Ph.D. Characterization of Dox Nephrotoxicity in Mice Wesley Runnels School of Science and Engineering Magnet Host: Genevieve Konopka, Ph.D. Transcriptional Networks Regulated by FOXP1 Rachana Vemireddy Plano East High School Host: David Boothman, Ph.D. Tumor-specific Targeting of the NAD+ Biosynthetic Pathway by Combining β-Lapachone with NamPT inhibitors 2013 Medical Center STARS Summer Research Program for Students STARS Associates Sarah Ahmed Mary Clare Beytagh Plano East Senior High School The Hockaday School Host: Thomas Carroll, Ph.D. Host: Kathryn O’Donnell, Ph.D. Debunking the Myths Behind WNT Signaling: Universal Beta Catenin Target Does Not Exist A “Sleeping Beauty” Mutagenesis Screen to Identify and Validate Novel Genes and Pathways Driving Lymphomagenesis Dylan Altschuler St. Mark’s School of Texas Host: Robin Hiesinger, Ph.D. Aarohan Burma St. Mark’s School of Texas Host: Robert Bachoo, M.D., Ph.D. The “Lattice Shift Model” of Neural Superposition in the Drosophila Eye Analysis of Temozolomide Resistance in Glioblastoma Mason Amelotte Jonah Donnenfield Jesuit College Preparatory School of Dallas Highland Park High School Host: Joseph Takahashi, Ph.D. Host: Deborah Clegg, Ph.D. Novel Findings Implicate Inverse Relationship Between MT-3 and ERα Patrick Arraj Jesuit College Preparatory School of Dallas Host: Jin Jiang, Ph.D. A Kinome-Wide RNAi Screen for Regulators of Intestinal Stem Cell Proliferation and Regeneration Phenotypic Characterization of Mice Heterozygous for a Novel ENU-Induced Mutation in Melanocortin-4 Receptor 2013 Medical Center STARS Summer Research Program for Students STARS Associates Angela Hillsman John Rivera Greenhill School Greenhill School Host: Doris Lambracht-Washington, Ph.D. Host: Christopher Derderian, M.D. Establishment of an Assay to Test for the Cytotoxicity of Amyloid Beta Peptides and the Potential Neuroprotective Effects of Aβ Antibodies Adipose Derived Stromal Vascular Cells Delay the Onset of Radiation-Induced Skin Injury Amy Tao The Hockaday School Trevor Johnson Jesuit College Preparatory School of Dallas Host: Dwight German, Ph.D. Do Pediatric Infant Vaccines Affect Brain Structure? Alexis Jones The Hockaday School Host: Yuh Min Chook, Ph.D. Deciphering the Hexapeptide Mutations of hnRNPAs in ALS Traian Pop School for the Talented and Gifted at Yvonne A. Ewell Townview Center Host: Rolf Brekken, Ph.D. Generation of PS-Negative Tumor-Derived Exosomes Host: Kim Orth, Ph.D. Vibrio Parahaemolyticus’s VopQ Interacts with the Host Lysosomal Membrane, Disturbing Cellular Homeostasis