HAPPY THURSDAY
-(6th Period)Have out your Notecard Sticker Sheet. Lay out your notecards (definition side up) on your desk 6x5 “Allele”
needs to be top left card.
-For Today “sketch” this karyotype and explain what gender this person is.
Unit 4 – Cell Cycle
Definitions Due Friday (11/6/15)
All Parts Due Friday (11/13/15)
Period 6 – All Parts Due Thursday (11/12/15)
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
Allele
Anaphase
Cancer
Cell Cycle
Centriole
Centromere
Chromatid
Chromosome
Crossing Over
Cytokinesis
Daughter Cell
12. Diploid
13. Electrophoresis
14. Frameshift
Mutation
15. Gamete
16. Gene
17. Genetic Disorder
18. Genome
19. Haploid
20. Interphase
21. Karyotype
22. Meiosis
23.
24.
25.
26.
27.
28.
29.
Pg 54
Metaphase
Mitosis
Mutation
Offspring
Point Mutation
Prophase
Sexual
Reproduction
30. Somatic
31. Telophase
32. Tumor
Page 65 – Mutations
Coloring
Essential Question
What is a mistake in the
genetic sequence?
Collect Today
Page 63 – Build a Karyotype
Notecard ALL PARTS - Period 6
Assigned
Page 65 – Mutations Coloring (TOMORROW)
Notecard ALL PARTS - Periods 1-5 (TOMORROW)
Cell Cycle/Vocabulary Make-Up Quiz (Friday)
Most Missed Quiz Make-Up (Friday)
IBB Quiz (Next Week)
Late
Notecard Sticker Sheet (-30 points)
Page 61 - Mitosis vs Meiosis (-50%)
Page 62 – Mitosis Meiosis Summary Modeling (-50%)
Essential Question
Pg 64
What is a mistake in the
genetic sequence?
Standard
B.6H – Describe how techniques such as DNA fingerprinting,
genetic modifications, and chromosomal analysis are used to
study the genomes of organisms
Think about it:
What happens if our DNA gets messed
up?
Cells sometimes make mistakes when copying their own
DNA.
These mistakes are called mutations.
Mutations are changes in the genetic material.
Mutations that produce changes in a single gene are known as gene
mutations.
Mutations that produce changes in whole chromosomes are known as
chromosomal mutations.
If a nucleotide is added or deleted, the bases are still read in groups
of three, but now those groupings are shifted for every codon that
follows. This is known as a frameshift mutation.
Gene mutations
involving changes in
one or a few
nucleotides are
known as point
mutations.
The three types of
point mutations are
substitutions,
insertions, and
deletions.
A small change in the
DNA of a single gene
affects the structure of
a protein, causing a
serious genetic
disorder.
(i.e. Cystic fibrosis,
sickle cell disease)
Mutations that
cause dramatic
changes in protein
structure are often
harmful because the
defective proteins
disrupt normal life
activities for the
individual.
Genetic Mutations: Your Name
1.Copy the chart below.
2.Write your name in the first box.
3.Put a box around each codon.
Name:
E N R I Q U EGA R Z A
Insertion (add a base
to the end into the
sequence)
ENR IQU
Deletion (take a base
away)
Insertion(add a base)
EGA R Z A K
Name: (Original
Strand)
Insertion (add a base
to the end into the
sequence)
Deletion (take a base
away)
E N R I Q U EGA R Z A
ENR IQU
EGA
RZA
ENR IQU
EGA
RZA
GAR
ZA
ENR
IUE
Q
K
Point Mutation
Frameshift Mutation
ENR IQU
EGA
RZA
Substitution (replace a JNR IQU
base)
ENR IQU
EGA
RZA
EGA
RZA
Point Mutation
Think-Pair-Share
Which would more likely have a bigger
effect on an organism, a point mutation
or frameshift mutation?
Why?
Sickle Cell Anemia
These are the sickle-shaped blood cells of someone with sickle cell anemia.
Sickle cell anemia is the result of a point mutation, a change in just one
nucleotide in the gene for hemoglobin. This mutation causes the hemoglobin
in red blood cells to distort to a sickle shape when deoxygenated. The sickleshaped blood cells clog in the capillaries, cutting off circulation.
Having two copies of the mutated genes cause sickle cell anemia, but having
just one copy does not, and can actually protect against malaria - an example
of how mutations are sometimes beneficial.
Color Blindness
• Most forms are caused by a point mutation on the X
chromosome.
What number do you see? A
color blind person won’t see
anything. A color deficient
person may see the number 35
Achondroplasia
•This is the most
common form of
dwarfism. It is
caused by a
substitution
mutation for the
gene that codes for
bone growth.
Genes located close together
on the same chromosomes
are linked, meaning that they
tend to be inherited
together.
Genes located on the sex
chromosomes are said to be
sex-linked genes. The X
chromosome contains more
information than the Y
chromosome.
The 4 kinds of chromosomal mutations are: deletions,
duplications, inversions, and translocations.
Duplication
Deletion
Inversion
Translocation