WATER SOLUBLE VITAMINS

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VITAMINS

• “

VITAMIN” means “vital for life”

• VITAMINS are organic compounds which are necessary in small quantities ( mg or µg

Micronutrients) for everyday healthy functioning of the body

1

Active form

• The structural form that performs its function (exhibits activity) within the organism .

• Human cannot synthesize sufficient quantities of vitamins; thus, vitamins must taken from other sources (diet or pill)

2

The general symptoms of any vitamin deficiency

• Frequent illness

• Slow healing wounds

• tiredness

MACalvey/Teachnet/Vitamins 2006 3

VITAMINS -

Two main categories

Water soluble

B

C

Fat Soluble

E

K

A

D

4

Water soluble

• Have more oxygen and nitrogen in their structure

• Cannot be stored in body

- regular supply needed

Fat Soluble

• Have significant hydrocarbon portions in their structure

• Can be stored in body regular supply not needed

• Excess is excreted in urine - no danger of toxic levels

• Can accumulate to toxic levels if large amounts ingested

• Unstable to heat and light, leach into cooking liquids

• Fairly stable at normal cooking temperatures

5

WATER SOLUBLE VITAMINS

Vitamins B and C

• Functions

• Effects of deficiency

• Sources

• RDA

B Vitamins

are important for healthy skin and nervous system

• Vitamin B1 (thiamine)

• Vitamin B2

• Vitamin B3

• Vitamin B5

(riboflavin)

(niacin or niacinamide)

(pantothenic acid)

In general, the B complex is important for healthy skin and nervous system

• Vitamin B6

(pyridoxine, pyridoxal, or pyridoxamine, or pyridoxine hydrochloride)

• Vitamin B7

(biotin)

• Vitamin B9

(folic acid)

• Vitamin

B12 (various cobalamins; commonly cyanocobalamin in vitamin supplements)

7

B complex Vitamins

Vitamin B

1

- Thiamine

Deficiency

Functions

• Essential for release of energy from arbohydrates

(coenzyme)

• Necessary for appetite and good health

• Needed for normal functioning of nervous system

• Beri-beri disease of nervous system

Common in countries where polished rice is staple food

8

Vitamin B

1

Sources

• Meat and liver

• whole-grain

• spinach

- Thiamine

9

Vitamin B

1

- Thiamine

RDA

1mg per day -

Requirement increases with energy expenditure

RDA R ecommended D aily A llowance

10

Vitamin B

2

-Riboflavin

Functions

• Metabolism of carbohydrates, proteins and fats (coenzyme

FMN, FAD)

• Growth, repair, development of body tissues - healthy skin, eyes and tongue

• The principal growth promoting factor in the vitamin B complex

Deficiency

• Loss of appetite

• Swollen tongue, cracked lips, eye infection, dermatitis

11

Vitamin B

2

-Riboflavin

Sources

• liver

• Milk

• Cheese

• Leafy Vegetables

12

Vitamin B

2

-Riboflavin

RDA

1 - 1.5 mg per day

13

Vitamin B3 -Niacin (Nicotinic acid)

Functions

• Metabolism of carbohydrates, proteins and fats (coenzyme

NAD,NADP)

• Needed for normal functioning of nervous system

Deficiency

• Pellagra

Symptoms

• loss of appetite

• mental disorder diarrhea

• possible death

14

Vitamin B 3 -Niacin (Nicotinic acid)

Sources

Liver meat

Yeast extracts

Milk

Cheese

Vegetables grains

MACalvey/Teachnet/Vitamins 2006 15

Vitamin B3 -Niacin (Nicotinic acid)

*RDA

*Related to protein intake

15 - 20mg per day

MACalvey/Teachnet/Vitamins 2006 16

Vitamin B

6

-Pyridoxine

Functions

• Protein metabolism

(coenzyme)

• Involved in formation of haemoglobin, hormones and structural proteins

• Healthy development of nervous system

MACalvey/Teachnet/Vitamins 2006

Deficiency

• Tiredness and

Fatigue, irritability

• Premenstrual tension

17

Vitamin B

6

-Pyridoxine

Sources

Meat

Fish

Nuts bananas

MACalvey/Teachnet/Vitamins 2006 18

Vitamin B

6

-Pyridoxine

RDA

2mg per day

MACalvey/Teachnet/Vitamins 2006 19

Vitamin B

12

- (CyanoCobalamin)

Functions

Vit B12 is necessary for the

• Red blood cell formation

• nervous system function

• the prevention of certain forms of anaemia and neurological disturbances

• functions primarily as a coenzyme in intermediary metabolism

Deficiency

• Pernicious anaemia

• Nerve degeneration

20

Vitamin B

12

- (CyanoCobalamin)

Sources

• Meat Liver

• Fish

• Cheese

• Cereals

This vitamin is stable to cooking

21

Vitamin B

12

- (CyanoCobalamin)

RDA

3-4 µg per day

22

Vitamin B9 -Folic Acid

Functions

• Red blood cell formation

• Essential for synthesis of

DNA and RNA (coenzyme)

• Development of brain, spinal cord and skeleton in foetus

Deficiency

• Fatigue in mild cases

• Anaemia in severe cases

Important to take folic acid prior to pregnancy and vital during first 3 months pregnancy

23

Vitamin B9 -Folic Acid

Sources liver

Fortified cereals

Green leafy vegetables

Potatoes

Milk

24

Vitamin B9 -Folic Acid

RDA

300 µg per day

More during pregnancy

25

Pantothenic acid

Functions

• Nessessary for the biosynthesis of coenzyme A

Deficiency

• Unknown

Sources

Pantothenic derives from

Greek word meaning from every where

26

Biotin

Functions

• A coenzyme important in lipid and carbohydrates metabolism.

Deficiency

• Unknown

Sources

Bacteria in the intestine synthesize biotin in sufficient quantities

27

Vitamin C -Ascorbic Acid

Functions

• Formation of connective tissue, collagen

• Critical to immune system

• Helps absorption of iron

• Prevents scurvy

• Promotes healing of wounds and healthy blood vessels

• Acts as antioxidant, protects HDL cholesterol

Deficiency

• Weakening of connective tissue

• Susceptibility to infection

• Incomplete iron absorption

• Delayed healing of wounds

28

Vitamin C -Ascorbic Acid

Sources

• green peppers

• Kiwi

• Citrus fruits, strawberries,

• Spinach

• broccolli

29

Vitamin C -Ascorbic Acid

Properties

• Acts as an antioxidant

RDA

30-60 mg per day

Least stable of all vitamins

30

FAT SOLUBLE VITAMINS

Vitamins A,D,E,K

• Functions

• Effects of deficiency

• Sources

• RDA

MA Calvey/Teachnet/Vitamins 2006 31

Vitamin A - Retinol and Beta-Carotene

Retinol Beta-Carotene

 Named because of its concern with retina of eye

 Only found in animal foods

Present with chlorophyll in plants, converted to

Vitamin A in gut wall

Vitamin A - Retinol and Beta-Carotene

Functions

• Important to vision

Necessary for production of Rhodopsin - pigment in retina, helps eye adapt to dim light

• Regulates growth

• Promotes healthy skin

• Maintenance of healthy epithelial tissues

Effects of deficiency

• Night blindness

• Retarded growth, malformed bones

• Dry mucous membranes

• Xerophthalmia - dry eye membrane

• Susceptibility to infection

Vitamin A - Retinol and Beta-Carotene

Sources

Retinol - liver oil, Liver,

Dairy products, Egg yolk

Beta-Carotene

Dark green leafy vegetables, Broccoli,

Carrots, Deep orange fruits and vegetables

Carotene

Go for Color!

Think

Yellow , Orange ,

Red, Deep Green

Vitamin A - Retinol and Beta-Carotene

Properties

• Powerful antioxidant

RDA

600 µg per day

90% of

Vitamin A in the body is stored in the liver

Vitamin D - Calciferols

Cholecalciferol

Ergocalciferol

The sunshine

Vitamin!

The sun activates Provitamin

7 dehydro cholesterol present in fat under skin

Formed by action of ultra violet light on fungi and yeasts

Manufactured synthetically for use as vitamin supplement

Provitamin 7 dehydro cholesterol

Cholecalciferol

Vitamin D -Calciferols

Functions

• Absorption and laying down of calcium and phosphorous in bones and teeth

• Regulates calcium balance between bones and blood

• Prevents rickets

Effects of deficiency

• *Rickets in children and

*osteomalacia in adults

* Conditions where bones are soft and cannot weight of body

• **Osteoporosis

**Bones become light, less dense and prone to fractures

• Dental caries

Vitamin D -Calciferols

Sources

Sunlight conversion

Fish liver oils

Dairy products

Oily fish

Margarine

Vitamin D -Calciferols

Properties

RDA

7 -10 µg per day

Probably the most stable of the vitamins

Vitamin E -Tocopherols

Anti coagulants and anti oxidants

Functions

• Powerful antioxidant

• May reduce risk of heart disease, stroke, cancer

• Improves absorption of vitamin A

Effects of deficiency

• Deficiency is rare

• Linked to conditions associated to malabsorption of fat

Vitamin E -Tocopherols

Sources

Wheatgerm

Oatmeal

Oils and animal fats

Leafy greens

Eggs

Vitamin E -Tocopherols

Properties

• Acts as antioxidant, delays rancidity and oxidation

RDA

Based on polyunsaturated fatty acid intake

Sometimes called

“Coagulation” vitamin

Vitamin K

Functions

• Constituent of prothrombin which is necessary in blood clotting

Effects of deficiency

• Abnormal clotting, bleeding and haemorrhaging

• Deficiency is rare because intestinal bacteria produce sufficient quantities

Vitamin K

Sources

• Dark green vegetables

• Liver

• Lean meat

• Eggs

• Manufactured by bacteria in intestine

RDA

No established recommendation

How vitamins help each other

• Vitamin E keeps Vitamin A from being destroyed in the intestines

• Vitamin D enables the body to absorb calcium and phosphorous

• Vitamin C helps folate build proteins

• Vitamin B

1 works in digestive system with niacin, pantothenic acid acid and magnesium

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