Development Chapter 29 Fertilization • • Zygote undergoes a series of mitotic cell divisions called cleavage zygote 2-cell stage 4-cell stage 8-cell stage morula blastocyst gastrula Morula = solid sphere of cells (day 5) Blastocyst = hollow ball of cells (days 6-7), it produces human chorionic gonadotropin (hCG) hormone which can be detected in the woman’s urine during a pregnancy test; source of embryonic stem cells Gastrula = differentiation starts; contains three germ layers (ectoderm, endoderm, mesoderm; days 7-10) Late Gastrula Endoderm Ectoderm Mesoderm Three germ layers in gastrula: Ectoderm – gives rise to the nervous system and skin Endoderm – gives rise to lining of the gut and internal organs Mesoderm – gives rise to skeleton, muscles, circulatory system, reproductive system Pregnancy becomes established during days 10 -14: • Fluid filled amniotic cavity starts to form • Yolk sac starts to form (will make blood cells, germ cells) • Embryo starts to form from embryonic disc • Chorion (placenta) starts to form and will supply the embryo with nutrients and eliminate wastes • Woman misses period Development of the Placenta • Embryo = the term used until the 8th week; from Greek “swelling within” • Fetus = the term used from the 8th week until birth; from Greek “offspring” Pregnancy can be divided into three trimesters: • First trimester = body systems form (during this time the embryo is extremely sensitive to smoking & drugs) • Second & third trimesters = continued body growth BIRTH 3 parts: 1. Dilation of cervix 2. Expulsion of the baby 3. Expulsion of the placenta