Laura Spenceley Task 1 - Cardiovascular Anatomy & Physiology Function The heart plays a unique role as an organ within the human body and has 5 main functions which are outlined below: 1. Transporting Oxygen and Removing Carbon Dioxide A primary function of the circulatory system is to supply oxygen to all cells in the body. Each cell in the body requires a constant supply of oxygen to function efficiently. Because most of the cells aren’t in any contact with air, the circulatory system must supply them with oxygen. Whilst a person inhales, air passes into the lungs, and oxygen is then absorbed across the membrane of the lungs into the bloodstream. This oxygenated blood is pumped through the heart to thinner blood vessels throughout the body. In the capillaries, oxygen diffuses out of blood and into cells. Simultaneously, CO2 produced by the cells is reabsorbed into blood, this then returns to the lungs and releases CO2 and picks up more oxygen. 2. Transporting Nutrients and Removing Waste Materials – A secondary vital function of the circulatory system is to provide all the cells throughout the body with nutrients and energy. When food is digested in the stomach, it moves through the intestines, where nutrients from food are absorbed into the bloodstream. Additionally the blood absorbs glucose from the liver. Energy and nutrients are then transported to all cells in the body Blood also absorbs waste products which are produced by the cells and transports them to the excretory organs in the body. 3. Fighting Disease – As well as nutrients and oxygen, the blood also carries essential disease-fighting cells. The organs of the immune system, like the spleen, create many types of specialized cells that can destroy foreign cells which may be trying to invade the body. The circulatory system is responsible for transporting these cells from the immune system to all other parts of the body. 4. Transportation of Hormones – Hormones are essential chemical signals that the body uses to communicate with itself. Hormones control many things such as growth, reproductive cycle and glucose metabolism. Hormones are created in parts of the body such as the brain or the liver then must be transported to another part of the body by the cardiovascular system in order to deliver the message adequately. 5. Regulation of Body Temperature – The cardiovascular system is also essential in regulating body temperature. If body temperature rises too high, blood vessels close to the skin dilate and increase in size. A larger surface area of blood vessels close to the skin means that more heat is conducted across the skin into the air. Contrariwise, if there is a drop in body temperature blood vessels constrict and decrease in size. The smaller surface area of blood vessels next to the skin causes less heat to be lost across the skin and retains more heat in the body. Laura Spenceley Task 1 - Cardiovascular Anatomy & Physiology Structure The heart is a cardiac muscle which works involuntary. The heart is comprised of four chambers, the upper chambers are known as the atria, which receive blood, the lower chambers are known as the ventricles which expel blood into the arteries. There are four chambers separating the chambers: Tricuspid valve – separates right atrium from right ventricle Pulmonary valve – separates the right ventricle from the pulmonary artery Bicuspid valve – separates the left atrium from the left ventricle Aortic valve – separates the left ventricle from the Aorta The heart is composed of three layers: Epicardium – outer layer of the hearts tissue which gives it a smooth texture Myocardium – the thick middle layer of cardiac muscle fibres which connect to electrical synapses, responsible for the contraction and relaxation of atria and ventricles. Endocardium – inner most layer of the heart which is composed of connective tissues and lines the cavities and valves. The endocardium regulates contractions of the heart, aids cardiac development and may regulate composition of blood which feeds the tissues of the heart. The right side of the heart receives deoxygenated blood and the left side of the heart receives oxygenated blood. Vital Statistics - There are 2 main vital statistics which doctors and health professionals use to assess the immediate health of your heart: blood pressure and pulse rate, as the condition of your heart changes due to health or environmental factors these statistics will fluctuate accordingly. Blood pressure (BP) – is the pressure of blood in your arteries. To ensure blood is pumped around the body efficiently there must be a certain pressure of blood in your arteries. During different stages of the heartbeat cycle the pressure of blood in your arteries changes. Blood pressure readings give off two numbers, diastolic and systolic pressure. Systolic pressure is the top number when a BP is written and is the highest pressure in your arteries when your heart contracts and pushes blood through your arteries. Laura Spenceley Task 1 - Cardiovascular Anatomy & Physiology Diastolic pressure, the bottom number when written, is the lowest level the blood in your arteries reaches as your heart relaxes between contractions. The diagram above shows the technique of taking blood pressure and how readings are taken. It is important to regularly have your blood pressure taken if you are on medication, have a disease, condition or illness which may affect your blood pressure and heart or are over a certain age. The average blood pressure for healthy adults ranges from 90/60 to 140/90. Pulse Rate - Your pulse is the rate at which your heart beats. Your pulse is usually called your heart rate, which is the number of times your heart beats each minute (bpm). But the rhythm and strength of the heartbeat can also be noted, as well as whether the blood vessel feels hard or soft. Changes in your heart rate or rhythm, a weak pulse, or a hard blood vessel may be caused by heart disease or another problem. As your heart pumps blood through your body, you can feel a pulsing in some of the blood vessels close to the skin's surface, such as in your wrist, neck, or upper arm. Counting your pulse rate is a simple way to find out how fast your heart is beating. Average Pulse Rates: - Adult Females: 76 to 80 - Adult Males: about 72 - Newborns: up to 140 - Children: about 90 - Elderly: 50 to 65 How does the heart work with blood and blood vessels to maintain vital functions? As earlier outlined the heart has 5 main functions which ensure blood is healthy, nourishing, clean, functions effectively and pumped adequately around the body. The heart works together with the blood and blood vessels to maintain these 5 functions. So what are blood vessels? There are 3 main types of blood vessel: Arteries - The walls (outer structure) of arteries contain smooth muscle fibre that contract and relax under the instructions of the sympathetic nervous system. The arteries transport blood away from the heart and Transport oxygenated blood only (except in the case of the pulmonary artery). Veins - The walls of veins consist of three layers of tissues that are thinner and less elastic than the corresponding layers of arteries. Veins include valves that aid the return of blood to the heart by preventing blood from flowing in the reverse direction. Veins transport blood towards the heart and transport deoxygenated blood only (except in the case of the pulmonary vein). Capillaries - Capillaries are extremely narrow blood vessels with a diameter of one cell thick. Capillaries are the smallest of all blood vessels and form the connection Laura Spenceley Task 1 - Cardiovascular Anatomy & Physiology between veins and arteries. As arteries branch and divide into arterioles and continue to reduce in size as they reach the muscle they become capillaries. Here the capillaries form a capillary bed, which is a vast expanse of very small vessels forming a network throughout the muscle. However, unlike veins and arteries, their main function is not transporting blood. They are specially designed to allow the movement of substances, mainly gases oxygen and Carbon Dioxide into and out of the capillary. How they work together with heart – Blood vessels work together with the heart to supply the main 5 functions of the heart with blood. Task 2 shows how blood is pumped around the body by the heart and blood vessels in more detail. The hearts contractions pump blood out of the heart via arteries which carry oxygenated blood around the body to all cells which require a fresh supply of oxygen for prime function. Arteries divide as they leave the heart and branch into smaller arteries. Smaller arteries have more smooth muscle tissue to control the changing pressure in blood flow due to the hearts contractions. Veins carry deoxygenated blood back towards the heart so blood cells can be replenished with fresh oxygen. This carrying back to the heart for oxygenation is essential for the functioning of all cells which require oxygen. Capillaries are essential for the effective movement of substances from red blood cells in capillaries into muscle cells. There are 3 main types of blood cell: Red blood cells (Erythrocytes) – Made in the bone marrow of some bones, including ribs, vertebrae and some limb bones. Produced at a very fast rate. Transport O2 from lungs to all respiring tissues. Prepare CO2 for transport from all respiring tissues to lungs. Contain haemoglobin (Hb), a red iron containing pigment which can carry O2. In the lungs, Hb combines with O2 to form oxyhaemoglobin. In other organs, oxyhaemoglobin splits up into Hb and O2. They have no nucleus so can fit more Hb inside the cytoplasm They have a special biconcave disc shape therefore increases the surface area and makes the diffusion of oxygen into & out of the cell easier. Old red blood cells are broken down in the liver, spleen and bone marrow. Some of the iron from the Hb is stored, and used for making new Hb, some of it is turned into bile pigment and excreted. White blood cells ( Leukocytes) – Made in the bone marrow and in the lymph nodes. They have a nucleus, often large and lobed. They can move around and squeeze out through the walls of blood capillaries into all parts of the body. There are different kinds of white blood cells. They all have the function of fighting pathogens and to clear up any dead body cells in your body: Laura Spenceley Task 1 - Cardiovascular Anatomy & Physiology A) Phagocytes – 1. Can move out of capillaries to the site of an infection. 2. Remove any microorganisms that invade the body and might cause infection, engulf and kill them by digesting them. B) Lymphocytes – these blood cells produce antibodies to fight bacteria and foreign bodies, there are 2 types of Lymphocytes; 1. B-lymphocytes: secrete special proteins called antibodies in response to contact with their particular antigen, which may be an invading pathogen or a foreign tissue that has been transplanted. 2. T-lymphocytes: attack foreign or infected cells and kill them. Platelets (Thrombocytes) – They are round biconvex disc cells They do not have a distinct nucleus Platelets stick to the damaged portion of endothelium layer and prevent loss of blood. The platelets are not allowed to stick to the strong, healthy endothelium due to the secretion of a substance called prostacyclin. When exposed to the air, due to a cut or open abrasion, platelets break down further and react with fibrogen. Vitamin K and Potassium aid Fibrogen to form a mesh of threads at the site of the abrasion and which collects red blood cells. In turn this makes a plug or clot as the open blood vessels dry. All 3 types of blood cells work together with the heart to help maintain the hearts vital functions. Whilst blood cells are being pumped around the body by the heart there a number of vital functions which are able to occur, these include; Fresh oxygen supply can be effectively maintained and delivered to all cells. CO2 can be effectively removed from cells and discarded. Bacteria and foreign bodies are fought by white blood cells and antibodies are secreted to respond to invading antigens. Laura Spenceley Task 1 - Cardiovascular Anatomy & Physiology