Crash Course Biology Notes on: DNA Structure and Replication Go the website below and click on the DNA Structure and Replication video and fill out the notes that follow the video. Under the video click options and check interactive transcript to have a written out version of everything said in the video. www.khanacademy.org/partner-content/crash-course1/crash-course-biology 1. The common name for Deoxyribonucleic acid is? 2. What does DNA store? 3. What do your genetic instructions do? 4. Are humans the only creatures with DNA? 5. How many chromosomes do somatic cells have? 6. How many DNA molecules does each chromosome contain? 7. Where are the chromosomes stored in the cell? Where is DNA stored? 8. What is DNA made of? 9. What is the structure of nucleic acids? a. 10. What does being a polymer mean? 11. The small repeating units of DNA are called what? 12. Link a bunch of nucleotides together and you have what? 13. What do you need to make a nucleotide? 1. 2. 3. 14. The sugar in DNA is called? It makes up the first part of its name. 1 Crash Course Biology Notes on: DNA Structure and Replication 15. What part of the DNA molecule holds the genetic coding that makes you, you? 16. What are the four nitrogenous bases? 17. Is DNA in living organisms a single polynucleotide molecule or a pair of polynucleotide molecules held together? 18. What is the structure of DNA called and what does this look like? 19. What are the main supports in the structure of DNA? 20. Describe how the sugar-phosphate bonds in DNA run to form the backbone. Be detailed in your description. 21. What links the two chains of DNA together? What type of bond do they have? 22. Can any pair of nitrogenous bases be linked? 23. What bases can be linked together? 24. What do we call bonded nitrogenous bases? 25. Which pairing is stronger and why? 26. What allows DNA to create you or any other organism? 27. In the DNA of one cell how many base pairs are there? 28. Have 5-prime AGGTCCG to 3-prime write the base sequence that appears on the other strand AGGTCCG 29. Could I make the same base sequence given above with a strand of RNA? Why? 30. What are the three major differences between RNA and DNA? 1. 2. 3. 2 Crash Course Biology Notes on: DNA Structure and Replication 31. Who discovered DNA? 32. How was Rosalind Franklin able to help discover the structure of DNA? 33. Who is given credit for discovering the structure of DNA and received a Nobel Prize for it? 34. What is DNA replication? 35. What does the enzyme helicase do? 36. Point where the splitting starts in DNA replication is known as the? 37. What is the top strand in DNA replication known as? 38. What is the bottom strand in DNA replication known as? 39. What can we use the two unwound sections of DNA for? 40. Why is it easier for the leading strand to make new DNA than for the lagging strand? 41. Describe how the leading strand makes a new DNA strand from itself. 42. Describe how the lagging strand makes a new DNA strand from itself. 43. What are the two jobs of DNA polymerase? 1. 2. 44. Draw a detailed picture of DNA and label all its parts. 3 Crash Course Biology Notes on: DNA Structure and Replication Read pages 293-299 and answer the section review. 1. __________________________________________________________________________________ __________________________________________________________________________________ 2. __________________________________________________________________________________ __________________________________________________________________________________ 3. 4. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 5. __________________________________________________________________________________ 6. __________________________________________________________________________________ Read pages 300-303 and answer the section review. 1. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 2. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 3. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 4. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 5. __________________________________________________________________________________ __________________________________________________________________________________ 4